Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)
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ClinicalTrials.gov Identifier: NCT00211705 |
Recruitment Status :
Completed
First Posted : September 21, 2005
Last Update Posted : December 4, 2006
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Hyperlipidemia | Behavioral: Diet Drug: Diet+pravastatin | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 8000 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Prevention |
Official Title: | Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study) |
Study Start Date : | February 1994 |
Study Completion Date : | March 2004 |

- Coronary Heart Disease(CHD)[fatal/non-fatal MI, sudden/cardiac death, angina, revascularization]
- Stroke, cerebrovascular infarction(CI), CHD+CI, all cardiovascular events, total mortality

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Ages Eligible for Study: | 40 Years to 70 Years (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- TC:220~270mg/dl
- Male: 40-70 years old/ female: postmenopausal-70 years old
- <40kg in weight
Exclusion Criteria:
- FH
- History of CHD(angina, MI, post-PTCA/CABG, etc.)
- History of CVA(stroke, TIA, etc.)
- Underlying malignant tumor

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00211705
Study Chair: | Haruo Nakamura, MD | Mitsukoshi Health and Welfare |
Other Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: | NCT00211705 |
Other Study ID Numbers: |
MEGA |
First Posted: | September 21, 2005 Key Record Dates |
Last Update Posted: | December 4, 2006 |
Last Verified: | June 2005 |
Hyperlipidemia coronary heart disease prevention stroke pravastatin |
Hyperlipidemias Hyperlipoproteinemias Hypercholesterolemia Dyslipidemias Lipid Metabolism Disorders Metabolic Diseases Pravastatin |
Anticholesteremic Agents Hypolipidemic Agents Antimetabolites Molecular Mechanisms of Pharmacological Action Lipid Regulating Agents Hydroxymethylglutaryl-CoA Reductase Inhibitors Enzyme Inhibitors |