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Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification
This study has been completed.
Sponsor:
Centers for Disease Control and Prevention
Collaborators:
Peking University
Ministry of Science and Technology of the People´s Republic of China
University of Florida
Information provided by:
Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:
NCT00207558
First received: September 13, 2005
Last updated: July 12, 2006
Last verified: September 2005
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Purpose
The aim of this study is to examine whether the same total daily dosage of folic acid, when taken as a single daily dose or as multiple divided doses throughout the day, results in different blood folate and homocysteine levels at the conclusion of the study. Further, a comparison of blood folate and homocysteine levels among women taking daily low-dosage (100mcg) and standard- dosage (400mcg) folic acid with those of women taking daily or weekly high-dosage (4000mcg) folic acid will be conducted.
| Condition | Intervention |
|---|---|
| Neural Tube Defects - Spina Bifida and Anencephaly | Drug: folic acid |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double-Blind Primary Purpose: Prevention |
| Official Title: | Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification |
Resource links provided by NLM:
Further study details as provided by Centers for Disease Control and Prevention:
Eligibility| Ages Eligible for Study: | 18 Years to 49 Years (Adult) |
| Sexes Eligible for Study: | Female |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
-women who have delivered a baby two to four years ago, whose child is still alive, who are not breast-feeding, who are not pregnant or planning to become pregnant within the next 9 months following enrollment, who are using an IUD for contraception, and who have not taken vitamin supplements during the past 3 months
Exclusion Criteria:
-women who have not delivered a baby two to four years ago, whose child is deceased, who are breast-feeding, who are currently pregnant or planning to become pregnant within the next 9 months following enrollment, who are not using an IUD for contraception, and who have taken vitamin supplements during the past 3 months
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00207558
Please refer to this study by its ClinicalTrials.gov identifier: NCT00207558
Locations
| China, Hebei | |
| Townships | |
| Xianghe County, Hebei, China | |
Sponsors and Collaborators
Centers for Disease Control and Prevention
Peking University
Ministry of Science and Technology of the People´s Republic of China
University of Florida
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| ClinicalTrials.gov Identifier: | NCT00207558 History of Changes |
| Other Study ID Numbers: |
CDC-NCBDDD-3970 U11/CCU015587-04-1 U11/CCU015586-05 |
| Study First Received: | September 13, 2005 |
| Last Updated: | July 12, 2006 |
Additional relevant MeSH terms:
|
Spinal Dysraphism Neural Tube Defects Anencephaly Nervous System Malformations Nervous System Diseases Congenital Abnormalities Abnormalities, Severe Teratoid |
Folic Acid Vitamin B Complex Hematinics Vitamins Micronutrients Growth Substances Physiological Effects of Drugs |
ClinicalTrials.gov processed this record on July 21, 2017