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Virtual Colonoscopy (VC) for Primary Colorectal Screening

This study has been completed.
National Naval Medical Center
Information provided by (Responsible Party):
University of Wisconsin, Madison Identifier:
First received: September 13, 2005
Last updated: June 17, 2016
Last verified: June 2016
This study involves a primary VC screening for colorectal polyps. The research hypothesis is that VC screening, including surveillance of sub-cm polyps, is a safe and effective approach.

Condition Intervention
Colorectal Polyps
Other: CTC surveillance

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: CT Virtual Colonoscopy for Primary Colorectal Screening

Resource links provided by NLM:

Further study details as provided by University of Wisconsin, Madison:

Primary Outcome Measures:
  • The growth rate (natural history) of small colorectal polyps [ Time Frame: The outcome measure of polyp growth rate is established at the time of surveillance CTC by comparing to the baseline CTC ]
    Polyp growth rates are established by comparing polyp volume at the initial and surveillance CTC studies

Enrollment: 272
Study Start Date: July 2004
Study Completion Date: June 2016
Primary Completion Date: June 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
In vivo surveillance of 6-9 mm polyps detected at CTC
Other: CTC surveillance
In vivo CTC surveillance of 6-9 mm polyp

Detailed Description:
The purpose of this study is to use virtual colonoscopy screening to learn more about what happens to small colon polyps (less than 10 mm) over time. From this, we can find out whether it's safer to remove all colon polyps right away or leave the small ones in place and remove only those that grow to 10 mm or more.

Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Screening population for colorectal cancer

Inclusion Criteria:

  • Medium-sized colorectal polyps (6-9 mm)

Exclusion Criteria:

  • No medium-sized colorectal polyps (6-9 mm)
  Contacts and Locations
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Please refer to this study by its identifier: NCT00204867

United States, Wisconsin
University of Wisconsin
Madison, Wisconsin, United States, 53792
Sponsors and Collaborators
University of Wisconsin, Madison
National Naval Medical Center
Principal Investigator: Perry J. Pickhardt, MD University of Wisconsin, Madison
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: University of Wisconsin, Madison Identifier: NCT00204867     History of Changes
Other Study ID Numbers: 2004-0104
Study First Received: September 13, 2005
Last Updated: June 17, 2016

Keywords provided by University of Wisconsin, Madison:
polyps processed this record on May 25, 2017