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Training at Different Intensities in Coronary Artery Disease -Effects on Myocardial Function

This study has been completed.
St. Olavs Hospital
Information provided by (Responsible Party):
Norwegian University of Science and Technology Identifier:
First received: September 16, 2005
Last updated: August 25, 2011
Last verified: August 2011
The study investigated if aerobic endurance exercise of different intensity has different impact on the physical capacity and myocardial function in patients with coronary artery disease. Patients with stable CAD trained for 10 weeks, and oxygen consumption and myocardial function were measured before and after this period. Patients were randomly assigned to each exercise group.

Condition Intervention
Coronary Artery Disease Behavioral: Exercise training for 10 weeks

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Which Training Intensity is Most Effective in Improving Myocardial Function in Patients With Coronary Artery Disease?

Resource links provided by NLM:

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Peak oxygen consumption

Secondary Outcome Measures:
  • Quality of life
  • Myocardial function measured by echocardiography

Enrollment: 17
Study Start Date: August 2002
Study Completion Date: January 2004
Primary Completion Date: January 2004 (Final data collection date for primary outcome measure)
Detailed Description:
Peak oxygen consumption was measured by gas-analysis. Myocardial function was measured by echocardiography. Exercise was performed on treadmills under close supervision of an exercise physiologist. Patients had to complete over 70% of sessions to be included in analysis. Three sessions were scheduled every week. Heart rate (HR) was about 85 % of max HR in the high intensity group, and about 65 % in the moderate intensity group.

Ages Eligible for Study:   20 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • stable coronary artery disease
  • over 4 months since cardiovascular event

Exclusion Criteria:

  • heart failure
  • inability to exercise
  Contacts and Locations
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Please refer to this study by its identifier: NCT00201591

Dept. of Circulation and Medical Imaging, NTNU
Trondheim, Norway, NO-7020
Sponsors and Collaborators
Norwegian University of Science and Technology
St. Olavs Hospital
Study Chair: Stig A Slørdahl, Prof Norwegian University of Science and Technology
  More Information

Responsible Party: Norwegian University of Science and Technology Identifier: NCT00201591     History of Changes
Other Study ID Numbers: Trehab I NTNU
Study First Received: September 16, 2005
Last Updated: August 25, 2011

Keywords provided by Norwegian University of Science and Technology:
Coronary artery disease
Exercise training
Aerobic Exercise

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases processed this record on September 21, 2017