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ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems

This study has been completed.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
University of Pittsburgh
Boston University
Information provided by:
Boston Medical Center Identifier:
First received: September 9, 2005
Last updated: May 5, 2010
Last verified: December 2007
The objective of this project was to test whether screening and brief intervention for unhealthy alcohol use leads to improved alcohol-related outcomes (such as alcohol consumption and linkage to alcohol assistance) and is cost-effective.

Condition Intervention Phase
Alcohol Dependence Alcohol Consumption Behavioral: Brief Intervention (adaptation of motivational interviewing) Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Hospital-based Brief Intervention for Alcohol Problems

Resource links provided by NLM:

Further study details as provided by Boston Medical Center:

Primary Outcome Measures:
  • Linkage to alcohol assistance
  • Change in drinks per day

Secondary Outcome Measures:
  • Change in the number of times a subject exceeded per occasion limits
  • Abstinence (dichotomous)
  • Change in drinks per day
  • Drinking risky amounts (dichotomous)
  • Binge drinking (dichotomous)
  • Hospitalization
  • Emergency Department visits
  • Health related quality of life
  • Readiness to change alcohol use

Estimated Enrollment: 350
Study Start Date: February 2001
Study Completion Date: April 2006
Detailed Description:

In this study the effectiveness and cost-effectiveness of brief intervention for unhealthy alcohol use in a diverse group of hospitalized medical patients was tested.

We conducted a randomized trial of medical inpatients with the whole spectrum of alcohol problems from risky use through dependence. Subjects in one group received standard care; subjects in the second group received a brief motivational intervention tailored to the severity of his or her alcohol problem. Primary outcomes are alcohol consumption and linkage to alcohol treatment. Additional outcomes include health-related quality of life, health care utilization, alcohol problems, and readiness to change. Costs, and clinical outcomes measured in quality-adjusted life years, a standard metric that allows comparison to other chronic illnesses, will be compared in a cost-effectiveness analysis.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 18 years of age or older
  • Fluent in English or Spanish
  • Consume risky amounts of alcohol
  • Provide 2 contacts to assist with follow-up
  • Have no plans to move from the local area within a year of screening
  • Score >21 on Mini-Mental State Examination (no serious cognitive impairment)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00183105

United States, Massachusetts
Boston Medical Center
Boston, Massachusetts, United States, 02118
Sponsors and Collaborators
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
University of Pittsburgh
Boston University
Principal Investigator: Richard Saitz, M.D., M.P.H. Boston Medical Center
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00183105     History of Changes
Other Study ID Numbers: NIAAASaitz12617-ASAP
P60AA013759 ( US NIH Grant/Contract Award Number )
NIH AA12617
Study First Received: September 9, 2005
Last Updated: May 5, 2010

Keywords provided by Boston Medical Center:
Alcohol abuse
Alcohol dependence
Alcohol consumption
Unhealthy alcohol use
Brief Intervention
Motivational Interviewing
Randomized trial
Unhealthy alcohol use (Risky alcohol consumption amounts, problem alcohol use, hazardous alcohol use, alcohol abuse and alcohol dependence)

Additional relevant MeSH terms:
Alcohol Drinking
Alcohol-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Drinking Behavior
Anti-Infective Agents, Local
Anti-Infective Agents
Central Nervous System Depressants
Physiological Effects of Drugs processed this record on June 28, 2017