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Collection of Bone Marrow Aspirate From Volunteer Donors

This study has been completed.
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Institute on Aging (NIA) ) Identifier:
First received: September 13, 2005
Last updated: August 3, 2012
Last verified: August 2012
The purpose of this study is to collect bone marrow cells for research purposes.


Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Collection of Bone Marrow Aspirate From Volunteer Donors for In Vitro Hematopoietic Research

Further study details as provided by National Institutes of Health Clinical Center (CC):

Biospecimen Retention:   Samples With DNA
Bone marrow aspirates Whole blood

Enrollment: 63
Study Start Date: July 2002
Study Completion Date: August 2012
Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Detailed Description:
This study is designed to provide bone marrow cells for other research studies. The research is being done because there are ongoing experiments in a number of National Institute on Aging (NIA) laboratories that require access to normal human bone marrow aspirate for their studies of the immune system. These studies are done to understand how blood cells are formed and how they function. Samples will be used to study problems such as the immune system in bone marrow failure and related conditions. Cells will be used in laboratory research and may be banked for future laboratory studies

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy males and females 18 years and older

Inclusion Criteria:

  • Healthy volunteers age 18 and over

Exclusion Criteria:

  • Significant abnormalities on health history questionnaire or in the results of blood tests
  • Pregnant or nursing mother
  • Participation in another research study within the past six weeks that is felt by the Principal Investigator to be incompatible with this study
  • Severe infection in the past two months
  • Immune disorder, or use of any medication that can alter immune system function
  • A medical or mental health finding showing inability to go through the procedure
  • Body mass index (BMI) greater than 29%
  • Chronic back pain, sciatica, or a compression fracture of the spine
  • Positive test results for viral infections: Hepatitis B, Hepatitis C, or HIV (AIDS)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00183066

United States, Maryland
NIA Clinical Research Unit located at Harbor Hospital
Baltimore, Maryland, United States, 21225
Sponsors and Collaborators
National Institute on Aging (NIA)
Principal Investigator: Dan L. Longo, MD National Institute on Aging (NIA)