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Effect of Antiseizure Medication on Hormone Levels and Sexual Function in Men With Epilepsy

This study has been completed.
Information provided by (Responsible Party):
Andrew Herzog, Beth Israel Deaconess Medical Center Identifier:
First received: September 12, 2005
Last updated: March 9, 2017
Last verified: March 2017
The purpose of this study is to determine if antiseizure drugs affect hormone levels and sexual function in men with seizures.

Seizure Disorder

Study Type: Observational
Study Design: Time Perspective: Other
Official Title: Antiseizure Medication-Induced Elevation of Serum Estradiol and Reproductive Dysfunction in Men With Epilepsy

Resource links provided by NLM:

Further study details as provided by Beth Israel Deaconess Medical Center:

Estimated Enrollment: 175
Study Start Date: October 1999
Estimated Study Completion Date: June 2006
Detailed Description:
This study involves donating two small tubes of blood for hormonal testing, which will be drawn at the same time as your routine blood draw for the monitoring of your antiseizure medication. You will also be asked to fill out a short confidential questionnaire regarding your sexual interest and function.

Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Must be a male between 18-50 years of age
  • Must have seizures
  • Must be on antiseizure medication for at least six months duration

Exclusion Criteria:

  • Must not have taken hormones, major tranquilizers or antidepressants for at least 3 months
  Contacts and Locations
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Please refer to this study by its identifier: NCT00179426

United States, Massachusetts
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215
Sponsors and Collaborators
Beth Israel Deaconess Medical Center
Principal Investigator: Andrew G. Herzog, M.D., M.Sc. Beth Israel Deaconess Medical Center
  More Information

Responsible Party: Andrew Herzog, Professor of Neurology, Beth Israel Deaconess Medical Center Identifier: NCT00179426     History of Changes
Other Study ID Numbers: 2001P000596
Study First Received: September 12, 2005
Last Updated: March 9, 2017

Keywords provided by Beth Israel Deaconess Medical Center:
Seizure Disorder
Sexual Function

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms processed this record on May 25, 2017