Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation
A study is being conducted by the University of Rochester Cancer Center (URCC) in which patients with liver cancer will be treated with high dose conformal radiation therapy. This type of radiation uses new techniques which aim the radiation to the sites of disease allowing the tumor to receive a high dose and the surrounding normal liver tissue to receive a low enough dose that the normal tissue should remain free from injury.
The purpose of the study is to determine if the conformal radiation therapy is safe, tolerable and effective in treating liver cancer and to determine the side effects caused by this treatment. A second objective is to determine if the levels of a special type of protein (called cytokines) found in the blood are related to this treatment.
|Liver Neoplasms Neoplasm Metastasis||Procedure: 3D Conformal Radiation Therapy and Radiosurgery||Phase 1 Phase 2|
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:||A Phase I/II Trial Of the Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation Delivered by 3D Conformal Radiation Therapy and Radiosurgery|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00178243
|United States, New York|
|University of Rochester, Dept. Radiation Oncology|
|Rochester, New York, United States, 14642|
|Principal Investigator:||Paul Okunieff, MD||Universtiy of Rochester, Dept of Radiation Oncology|