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Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

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ClinicalTrials.gov Identifier: NCT00172744
Recruitment Status : Unknown
Verified March 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 15, 2005
Last Update Posted : October 11, 2007
Sponsor:
Information provided by:
National Taiwan University Hospital

Brief Summary:
The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.

Condition or disease
Healthy

Detailed Description:
This study is to investigate the effect of the cyclic mechanical strain on the osteogenic differentiation of mesenchymal stem cells. Mesenchymal stem cells will be cultured from the periodontal ligament tissue of the premolars extracted due to orthodontic reason.

Study Type : Observational
Estimated Enrollment : 20 participants
Time Perspective: Prospective
Study Start Date : April 2005
Study Completion Date : July 2006




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Ages Eligible for Study:   13 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Orthodontic patients who need to have premolars extracted

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00172744


Contacts
Contact: Yi-Jane Chen, MSD 886-2-23123456 ext 6863 LCYC@ha.mc.ntu.edu.tw

Locations
Taiwan
School of Dentistry, College of Medicine, National Taiwan University Terminated
Taipei, Taiwan
School of Dentistry, College of Medicine, National Taiwan University Recruiting
Taipei, Taiwan
Contact: Yi-Jane Chen, MSD    886-2-23123456 ext 6863    LCYC@ha.mc.ntu.edu.tw   
Principal Investigator: Yi-Jane Chen, MSD         
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Yi-Jane Chen, MSD School of Dentistry, College of Medicine, National Taiwan University

ClinicalTrials.gov Identifier: NCT00172744     History of Changes
Other Study ID Numbers: 9361701291
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: October 11, 2007
Last Verified: March 2005

Keywords provided by National Taiwan University Hospital:
stem cells
periodontal cells
mechanical stress
differentiation
periodontal ligament