The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00172250
Recruitment Status : Completed
First Posted : September 15, 2005
Last Update Posted : November 24, 2005
Information provided by:
National Taiwan University Hospital

Brief Summary:

Elevation of plasma homocysteine has been recognized as one of the risk factors of atherosclerotic disease. The objectives of this study are: (1) to investigate the level of plasma homocysteine and the prevalence of hypehomocysteinemia (2) to find out the role of homocysteine in coronary artery disease and the proper cut-off point of plasma homocysteine to evaluate the presence of coronary artery disease; (3) to understand the control condition of tranditional risk factors of cardiovascular disease, especially hypertension, dyslipidemia, and diabetes mellitus.

The study subjects were recruited from the ambulatory setting of cardiology in National Taiwan University Hospital.

Condition or disease
Homocysteine Coronary Artery Disease

Study Type : Observational
Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Study Start Date : September 2003

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

Patient > 65 y/o or < 50y/o Scr<=1.5mg/dL

Exclusion Criteria:

  • Scr> 1.5mg/dl pregnancy alcohoism

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00172250

Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Juey-Jen Hwang, MD, PhD National Taiwan University Hospital Identifier: NCT00172250     History of Changes
Other Study ID Numbers: 9261701046
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: November 24, 2005
Last Verified: August 2005

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases