Employment-based Reinforcement of Naltrexone Ingestion and Abstinence
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|ClinicalTrials.gov Identifier: NCT00149669|
Recruitment Status : Completed
First Posted : September 8, 2005
Results First Posted : August 16, 2017
Last Update Posted : September 14, 2017
|Condition or disease||Intervention/treatment||Phase|
|Cocaine-Related Disorders Heroin Dependence Opioid-Related Disorders Substance Abuse, Intravenous||Behavioral: employment-based reinforcement||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||67 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Employment-Based Addiction Pharmacotherapy|
|Study Start Date :||December 2005|
|Actual Primary Completion Date :||December 2010|
|Actual Study Completion Date :||December 2010|
No Intervention: Work Plus Naltrexone Prescription
Participants were prescribed naltrexone, but were not be required to ingest it to work. Participants could work and earn money, independent of whether or not they continued to take naltrexone.
Experimental: Work Plus Naltrexone Contingency
Participants were required to ingest naltrexone to work, and received a brief pay decrease for missing a dose (employment-based reinforcement of naltrexone ingestion).
Behavioral: employment-based reinforcement
Work Plus Naltrexone Contingency participants were required to ingest naltrexone to work, and received a brief pay decrease for missing a dose.
- Percentage of Urine Samples Positive for Naltrexone [ Time Frame: 6 months ]The number of urine samples positive for naltrexone divided by the total number of urine samples times 100.
- Percentage of Urine Samples Negative for Cocaine [ Time Frame: 6 months ]the number of urine samples that were negative for cocaine divided by the total number of urine samples) x 100
- Percentage of Urine Samples Negative for Opiates [ Time Frame: 6 months ]The number of urine samples negative for opiates divided by the total number of urine samples times 100.
- HIV Risk Behaviors [ Time Frame: 6 months ]Behaviors that place participants at risk for acquiring or transmitting HIV
- Cost Benefit Analysis [ Time Frame: 6 months ]The costs and economic benefits of the intervention
- Percentage of Urine/Breath Samples Negative for Other Drugs of Abuse [ Time Frame: 6 months ]The percentage of urine and breath samples that are negative for other drugs of abuse
- Cocaine Positive Urine Samples [ Time Frame: 6 months ]The number of urine samples that were positive for cocaine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00149669
|United States, Maryland|
|The Center for Learning and Health|
|Baltimore, Maryland, United States, 21224|
|Principal Investigator:||Kenneth Silverman, Ph.D.||Johns Hopkins University|