Genetic Study of Nephrolithiasis in Gouty Diathesis
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ClinicalTrials.gov Identifier: NCT00149305 |
Recruitment Status
:
Terminated
(Non significative preliminary data)
First Posted
: September 8, 2005
Last Update Posted
: April 9, 2015
|
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Condition or disease | Intervention/treatment |
---|---|
Nephrolithiasis | Other: Genetic analyses |

Study Type : | Observational |
Actual Enrollment : | 37 participants |
Observational Model: | Case Control |
Time Perspective: | Prospective |
Official Title: | Genetic Study of Nephrolithiasis in Gouty Diathesis |
Study Start Date : | May 2005 |
Actual Primary Completion Date : | January 2010 |
Actual Study Completion Date : | May 2010 |

Group/Cohort | Intervention/treatment |
---|---|
Patients with gouthy diathesis | Other: Genetic analyses |
Healthy subjects | Other: Genetic analyses |

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Ages Eligible for Study: | 10 Years to 85 Years (Child, Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- male and female, ≥ 10 years of age
- uric acid or calcium oxalate nephrolithiasis
- urinary 24 h pH < 5.5 in absence of high animal protein intake (urinary sulphate excretion <25 mM/24 h after one week of low animal protein intake)
- familial history of kidney stones (at least two first or second degree family members affected)
- written informed consent according to the Declaration of Helsinki guidelines
Exclusion Criteria:
- renal colic in the 4 weeks preceding evaluations
- excessive gastrointestinal alkali loses
- inability to fully understand the purposes of the study or to provide a written informed consent

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00149305
Italy | |
Clinical Research Center for Rare Diseases | |
Ranica, Bergamo, Italy, 24020 |
Principal Investigator: | Erica Daina, MD | Mario Negri Institute |
Responsible Party: | Mario Negri Institute for Pharmacological Research |
ClinicalTrials.gov Identifier: | NCT00149305 History of Changes |
Other Study ID Numbers: |
GOUTY DIATESIS |
First Posted: | September 8, 2005 Key Record Dates |
Last Update Posted: | April 9, 2015 |
Last Verified: | October 2009 |
Keywords provided by Mario Negri Institute for Pharmacological Research:
Gouty diathesis Acid uric nephrolithiasis |
Additional relevant MeSH terms:
Nephrolithiasis Kidney Calculi Disease Susceptibility Kidney Diseases Urologic Diseases Urolithiasis |
Urinary Calculi Calculi Pathological Conditions, Anatomical Disease Attributes Pathologic Processes |