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Cognitive Training in the Elderly

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ClinicalTrials.gov Identifier: NCT00146263
Recruitment Status : Unknown
Verified September 2005 by Beersheva Mental Health Center.
Recruitment status was:  Recruiting
First Posted : September 7, 2005
Last Update Posted : September 8, 2010
Sponsor:
Information provided by:
Beersheva Mental Health Center

Brief Summary:

Background:

The aging of the population has lead to a significant increase in the number of older people suffering from cognitive impairment and dementia. The present lack of effective drug therapy for these conditions makes it imperative to investigate other potential therapeutic interventions.

Cognitive training has been described as possibly useful in improving cognitive function in elderly subjects with mild impairment and early dementia. However, there have been few well-designed studies to date and the results are equivocal. Most studies have relied on the use of paper-based neuropsychological assessment instruments with limited accuracy and reproducibility. The investigators have developed a validated computerized neuropsychological assessment battery with increased test-retest reliability.

The purpose of this study is to assess the efficacy of a computerized training program on cognitive function in older persons with normal cognition, mild cognitive impairment, and early dementia.

Description:

A randomized prospective AB/BA crossover study.

Methods:

Eligible males and females aged 60 years and older following initial computerized neuropsychological assessment will be randomized to receive either a 12-session computerized cognitive training program, or no treatment. Repeat neuropsychological assessment will be followed by a 4-week no treatment phase, reassessment and crossover phase. Repeat assessments will be performed at three and six months.


Condition or disease Intervention/treatment Phase
Dementia Behavioral: computerized cognitive training Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 300 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect of Computerized Cognitive Training on Neuropsychological Measures of Cognitive Function in the Elderly
Study Start Date : September 2005
Study Completion Date : June 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dementia
U.S. FDA Resources




Primary Outcome Measures :
  1. changes in cognitive function


Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age: above 60 years old

Exclusion Criteria:

  • Visual impairment
  • Educational inability to perform training

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00146263


Contacts
Contact: Tzvi Dwolatzky, MD 972-8-6401416 tzvidov@bgu.ac.il
Contact: Yaacov Grinshpun, MD 972-8-6401520 yaacovg@bgu.ac.il

Locations
Israel
Beersheva Mental Health Center Recruiting
Beersheva, Israel
Contact: Tzvi Dwolatzky, MD    972-8-6401416    tzvidov@bgu.ac.il   
Principal Investigator: Tzvi Dwolatzky, MD         
Sponsors and Collaborators
Beersheva Mental Health Center
Investigators
Principal Investigator: Tzvi Dwolatzky, MD Ben-Gurion University of the Negev

ClinicalTrials.gov Identifier: NCT00146263     History of Changes
Other Study ID Numbers: BMHC-4018CTIL
First Posted: September 7, 2005    Key Record Dates
Last Update Posted: September 8, 2010
Last Verified: September 2005

Keywords provided by Beersheva Mental Health Center:
mild cognitive impairment
dementia
Alzheimer's Disease
cognitive training

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders