Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality
Procalcitonin, a marker of infection has often been compared to clinical pictures as for instance "clinical sepsis". This has given som problems in the interpretation of these studies, because of the lack of good Gold Standards for "clinical sepsis. We have decided to investigate the development from day to day of Procalcitonin in the blood of intensive care patients, compared to the mortality.
Hypothesis: Procalcitonin increase after reaching a certain level predicts mortality in the Intensive Care Unit.
|Sepsis - to Reduce Mortality in the Intensive Care Unit|
|Study Design:||Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
|Official Title:||Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality|
|Study Start Date:||January 2002|
|Estimated Study Completion Date:||January 2003|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00144638
|Dept. 4131, Rigshospitalet, Cph University Hosp., DK|
|Copenhagen, Denmark, DK-2100|
|Principal Investigator:||Lars Heslet, MD, MD.Sc.||Dept. 4131, Rigshospitalet, Blegdamsvej 9, DK-2100|