We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00072917
First Posted: November 14, 2003
Last Update Posted: January 18, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Purpose
This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Condition
Obesity Thinness Weight Gain

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Biospecimen Retention:   Samples With DNA
Blood and urine

Estimated Enrollment: 100
Study Start Date: October 2003
Estimated Study Completion Date: June 2008
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   25 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Subjects have been recruited through advertisements in local news media and on the internet
Criteria
  • Half of the subjects will be women, half will be men,
  • age 25-35,
  • a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI>30.
  • Subjects should not engage in planned physical activity more than 3 hrs per week.
  • For the obesity prone group there should be at least 1 1st degree relative with a BMI>30.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00072917


Locations
United States, Colorado
University of Colorado Health Sciences Center
Denver, Colorado, United States, 80262
Sponsors and Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  More Information

Responsible Party: Daniel H. Bessesen, MD, University of Colorado School of Medicine
ClinicalTrials.gov Identifier: NCT00072917     History of Changes
Other Study ID Numbers: OVOPOB DK62874 (complted)
DK62874
First Submitted: November 12, 2003
First Posted: November 14, 2003
Last Update Posted: January 18, 2010
Last Verified: January 2010

Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):
obesity
thinness
weight gain
physical activity
diet
fat oxidation
hunger
feeding behavior
overfeeding

Additional relevant MeSH terms:
Obesity
Weight Gain
Thinness
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms
Body Weight Changes


To Top