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Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

This study has been completed.
Information provided by:
VA Office of Research and Development Identifier:
First received: July 3, 2001
Last updated: January 20, 2009
Last verified: December 2004
The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements in metabolic insulin action. In addition, the study will track whether these improvements are related to changes in blood pressure.

Condition Phase
Phase 1

Study Type: Observational
Official Title: Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

Resource links provided by NLM:

Further study details as provided by VA Office of Research and Development:


Ages Eligible for Study:   50 Years to 75 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Age 50 - 75 years, elevated blood pressure, BMI greater than 25 but less than 40 kg/m2
  Contacts and Locations
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Please refer to this study by its identifier: NCT00018304

United States, Minnesota
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Sponsors and Collaborators
VA Office of Research and Development
OverallOfficial: Arthur Leon, M.D.
OverallOfficial: Alan Blank, M.D.
  More Information Identifier: NCT00018304     History of Changes
Other Study ID Numbers: AGCG-005-98S 
Study First Received: July 3, 2001
Last Updated: January 20, 2009
Health Authority: United States: Federal Government

Keywords provided by VA Office of Research and Development:
blood pressure
insulin sensitivity
blood flow

Additional relevant MeSH terms:
Insulin, Globin Zinc
Hypoglycemic Agents
Physiological Effects of Drugs processed this record on October 21, 2016