Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow
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The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements in metabolic insulin action. In addition, the study will track whether these improvements are related to changes in blood pressure.
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Ages Eligible for Study:
50 Years to 75 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age 50 - 75 years, elevated blood pressure, BMI greater than 25 but less than 40 kg/m2