Effects of Home Visits on Medication Adherence in Children and Youth With HIV

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2001 by National Center for Research Resources (NCRR).
Recruitment status was  Active, not recruiting
Information provided by:
National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:
First received: November 4, 2000
Last updated: June 23, 2005
Last verified: November 2001
Adherence to complex medication regimens is critical to successful treatment of HIV infection. Unfortunately, adherence to medical regimens with conventional interventions averages 50% in chronic disease. We have observed that adherence barriers that were unrecognized by providers in the clinic setting have been detected during home visits. It is possible that recognition and interventions to resolve adherence barriers observed during home visits may improve adherence. This proposal will test the hypothesis that home-visits which identify previously unrecognized adherence barriers and provide support and education will increase medication adherence among children and youth with HIV infection and improve the patient/health care provider relationship. Specific aims of the study are: 1. Determine the impact of a series of home-visits on adherence to medication regimens for HIV infected youth and children. 1a. Adherence to medical regimens will be assessed before and after the series of home-visits using a self-report questionnaire and Microelectronic Monitoring System (MEMS) or in-home pill count. 1b. For each of these measures a percentage of adherence will be calculated and compared from a baseline to after the final home visit and after the six month follow up period. 2. Assess the changes in patient satisfaction from baseline to after the home-visits using a questionnaire completed by the patient/family. 3. Incorporate a pilot study to assess the changes in the provider's knowledge of the patient's family characteristics and home circumstances relevant to adherence following the home visits.

Condition Intervention
HIV Infections
Behavioral: Counseling in the home

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Primary Purpose: Educational/Counseling/Training

Resource links provided by NLM:

Further study details as provided by National Center for Research Resources (NCRR):


Ages Eligible for Study:   up to 24 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • HIV positive
  • English speaking
  • Live in Denver metro area
  • Taking >=1 antiretroviral medication
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00006439

United States, Colorado
The Children's Hospital
Denver, Colorado, United States, 80218
Sponsors and Collaborators
National Center for Research Resources (NCRR)
Principal Investigator: Elizabeth McFarland
  More Information

ClinicalTrials.gov Identifier: NCT00006439     History of Changes
Other Study ID Numbers: NCRR-M01RR00069-0622  M01RR000069 
Study First Received: November 4, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):

ClinicalTrials.gov processed this record on May 25, 2016