Insulin Resistance Atherosclerosis Study (IRAS)

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI) Identifier:
First received: May 25, 2000
Last updated: April 13, 2009
Last verified: April 2009

To conduct a multicenter study of the relationship between insulin resistance and cardiovascular disease (CVD) and its risk factors in a tri-ethnic (African-American, Hispanic, and non-Hispanic white) population aged 40 to 69 years at baseline. Also, to identify the genetic determinants of insulin resistance and visceral adiposity.

Cardiovascular Diseases
Diabetes Mellitus
Heart Diseases
Insulin Resistance

Study Type: Observational

Resource links provided by NLM:

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: September 1991
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

No eligibility criteria

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00005135

Sponsors and Collaborators
Investigator: Richard Bergman University of Southern California
Investigator: Donald Bowden Wake Forest School of Medicine
Investigator: Michael Bryer-Ash University of California, Los Angeles
Investigator: Steven Haffner University of Texas
Investigator: Jill Norris University of Colorado, Denver
Investigator: Marian Rewers University of Colorado Health Science Center
Investigator: Mohammed Saad University of Southern California
Investigator: Joseph Selby Kaiser Foundation Research Institute
Investigator: Lynne Wagenknecht Wake Forest School of Medicine
  More Information

Publications: Identifier: NCT00005135     History of Changes
Other Study ID Numbers: 1005
Study First Received: May 25, 2000
Last Updated: April 13, 2009
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Insulin Resistance
Arterial Occlusive Diseases
Cardiovascular Diseases
Glucose Metabolism Disorders
Metabolic Diseases
Vascular Diseases processed this record on March 26, 2015