Bogalusa Heart Study

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborators:
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Environmental Health Sciences (NIEHS)
Information provided by:
Tulane University
ClinicalTrials.gov Identifier:
NCT00005129
First received: May 25, 2000
Last updated: September 24, 2015
Last verified: September 2015
  Purpose
To determine the natural history of atherosclerosis, coronary artery disease, and hypertension in children and adults from birth to age 40 in a total biracial community.

Condition
Atherosclerosis
Cardiovascular Diseases
Heart Diseases
Coronary Disease
Hypertension

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Tulane University:

Enrollment: 12000
Study Start Date: June 1972
Estimated Study Completion Date: November 2019
Estimated Primary Completion Date: November 2019 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   Child, Adult, Senior
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
12000 individuals who have been examined as children and adults for over 40 years for heart disease risk factors.
Criteria
All previous participants of the Bogalusa Heart Study.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00005129

Locations
United States, Louisiana
Tulane University
New Orleans, Louisiana, United States, 70112
Sponsors and Collaborators
Tulane University
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Environmental Health Sciences (NIEHS)
Investigators
Principal Investigator: Lydia Bazzano, MD, PhD, MPH Tulane University
Principal Investigator: Wei Chen, MD, PhD Tulane University
Principal Investigator: Emily Harville, PhD Tulane University
  More Information

Publications:
Hunter SM, Croft JB, Burke GL, Vizelberg IA, Berenson GS: Social Influences and Longitudinal Patterns of Smokeless Tobacco Use. In: Health Implications of Smokeless Tobacco, NIH Consensus Development Conference, January 13-15, p. 32-37, 1986
Freedman DS, Newman WP III, Gard PD, Cresanta JL, Srinivasan SR, Tracy RE, Berenson GS: Atherosclerosis in Early Life - The Bogalusa Heart Study. Cardiol Board Rev, 3:26-40, 1986
Cohen JC, Buonagura K, Bickers J, Berenson GS, Rothschild H: Familial Clustering of Malignancies: Distribution of Ha-ras Restriction Fragment Length Polymorphisms in Normal and High Risk Populations. In: Proceedings of UCLA Symposia on Molecular and Cellular Biology, Vol 40 (Harris CC, Eds). New York: Alan R. Liss, Inc, p. 397-400, 1986
Webber LS, Freedman DS, Cresanta JL: Tracking of Cardiovascular Disease Risk Factor Variables in School-Age Children. In: Causation of Cardiovascular Risk Factors in Children (Berenson GS, Ed). New York: Raven Press, 1986
Webber LS, Freedman DS: Interrelationships of Coronary Heart Disease Risk Factors in Children. In: Causation of Cardiovascular Risk Factors in Children (Berenson GS, Ed). New York: Raven Press, 1986
Freedman DS, Srinivasan SR, Shear CL, Franklin FA, Webber LS, Berenson GS: Apolipoproteins A-I and B in Relation to Parental Myocardial Infarction - The Bogalusa Heart Study. Cardiol Board Rev, March:1-24, 1987
Berenson GS, Srinivasan SR, Shear CL, Webber LS: The Epidemiology of Coronary Artery Disease in Childhood. In: Cardiovascular Risk Factors in Childhood: Epidemiology and Prevention (Hetzel BS, Berenson GS, Eds). Amsterdam: Elsevier Science Publishers, B.V., p. 3-20, 1987
Freedman DS, Newman WP III, Tracy RE, Strong JP, Cresanta JL, Berenson GS: Pathology of Atherosclerosis in Childhood. In: Cardiovascular Risk Factors in Childhood: Epidemiology and Prevention (Hetzel BS, Berenson GS, Eds). Amsterdam: Elsevier Science Publishers, B.V., p. 83-99, 1987
Thompson B, Butcher AH, Berenson GS: Children's Beliefs About Sources of Health: A Reliability and Validity Study. Measure Eval Guid Develop, 20(20:80-88, 1987
Nicklas TA, Arbeit ML, Franklin FA, Johnson CC, Berenson GS: A Family Approach to Cardiovascular Risk Reduction Through Diet. J Nutr Educ GEM, 19:302A, 1987
Srinivasan SR, Freedman DS, Berenson GA: Are Plasma Apolipoproteins Helpful as Markers of Coronary Artery Disease? Int Med, 8:195-201, 1987
Johnson CC, Nicklas TA, Arbeit ML, Franklin FA, Berenson GS: A Comprehensive Model for Maintenance of Family Health Behaviors; The 'Heart Smart' Family Health Promotion Program. Family Commun Hlth, 11:1-7, 1988
Nicklas TA, Arbeit ML, Johnson CC, Franklin FA, Berenson GS: Intervention on Family Eating Behavior for Children at High Risk: Heart Smart Program. J Nutr Educ, 20:128-132, 1988
Voors AW, Webber LS, Berenson GS: A Consideration of Essential Hypertension in the Pediatric Age. Practical Cardiol, 3:29, 1977
Frerichs RR, Srinivasan SR, Webber LS, Berenson GS: Serum Cholesterol and Triglyceride Levels in Children From a Biracial Community - The Bogalusa Heart Study. International Workshop-Conference on Atherosclerosis, London, Ontario, Canada, September 1975. Atherosclerosis. (G.W. Manning and M.D. Haust Eds.) Plenum Publ. Corp, New York, p. 204, 1977
Berenson GS: Risk Factors in Children - the Early Natural History of Arteriosclerosis. Tokyo. In: Atherosclerosis IV, (G Schettler, Goto Y, Hata G, Klose, Eds.) Springer-Verlag, Berlin, Heidelberg, p. 489, 1977
Voors AW, Webber LS, Berenson GS: Relationship of Blood Pressure Levels to Height and Weight in Children. Cardiovasc Med, 3:911, 1978
Frank GC, Farris RP, Berenson GS: Dietitians' Response to Knowledge of Their Own Cardiovascular Risk. J Nutr Ed, 10:105, 1978
Berenson GS, Webber LS, Srinivasan SR, Frerichs RR, Voors AW: Interrelationship and Persistence of Risk Factor Variables at High Levels in Children - The Bogalusa Heart Study The 5th International Conference on Atherosclerosis, Milan, Italy, November 1977, (L. A. Carlson, R. Paoletti, C. R. Sirtori, and G. Weber, Eds.) Raven Press, New York, p. 357, 1978
Srinivasan SR, Berenson GS, Frerichs RR: Serum Lipids and Lipoproteins in Children. In: Atherosclerosis: Its Pediatric Aspects (W. B. Strong, Ed.) Grune and Stratton, New York, p. 85, 1978
Berenson GS: Children, the Next Generation of Patients with Myocardial Infarction. Proceedings of the International Kronberg Symposium, Frankfurt, Germany, May 1977. Changes in the Medical Panorama, (G. Schettler, J. Drews, and H. Greten, Eds.) Georg Thieme Publishers, Stuttgart, Germany, p. 75, 1978
Berenson GS, Voors AW, Webber LS: Blood Pressure Levels in Black and White Children Related to the Early Onset of Essential Hypertension. Proceedings, VIII World Congress of Cardiology, Tokyo. (S. Hayase and S. Murae, Eds.) Excerpta Medica, Amsterdam, p. 406-413, 1979
Berenson GS, Srinivasan SR, Webber LS: Prognostic Significance of Lipid Profiles in Children. In: Childhood Prevention of Atherosclerosis and Hypertension, (R.M. Lauer, and R.B. Shekelle, Eds.) Raven Press, New York, p. 75-86, 1980
Berenson GS, Srinivasan SR, Voors AW, Webber LS: Clues to Mechanisms of Cardiovascular Disease From an Epidemiologic Study of Children - The Bogalusa Heart Study. In: Atherosclerosis V (Gotto AM Jr, Smith LC, Allen B, Eds). New York: Springer-Verlag, p. 272-277, 1980
Voors AW, Berenson GS, Shuler SE, Webber LS: Blood Pressure, Electrolyte Clearance, and Plasma Renin Activity in Children Sampled From an Entire Community J Appl Biochem, 2:87-99, 1980
Voors AW, Webber LS, Berenson GS: Epidemiologia de la Hipertension Arterial en Ninos Estadunidenses. In: Hipertension Arterial 1980. First Interamerican Course on Hypertension, Mexico City, Feb. 1979 (Gonzalez Caamano A, Alcocer DB, L, Eds). Mexico City: Ediciones Medicas Actualizadas, SA, p.91-102, 1980
Voors AW, Webber LS, Berenson GS: Epidemiologia de la Hipertension Arterial an Adolescentes Estadunidenses. In: Hipertension Arterial 1980, First Interamerican Course on Hypertension, Mexico City, Feb. 1979 (Gonzalez Caamano A, Alcocer DB, L, Eds). Mexico City: Ediciones Medicas Actualizadas, SA, p. 103-115, 1980
Berenson GS, Voors AW, Webber LS: Importance of Blood Pressures in Children - Distribution and Measurable Determinants. In: Epidemiology of Arterial Blood Pressure (Kesteloot H, Joossens JV Eds). The Hague, Netherlands: Martinus Nijhoff Publishers, p. 71-97, 1980
Voors AW, Webber LS, Harsha DW, Frank GC, Berenson GS: Obesity: Determinants and Consequences in Children of An Entire Biracial Population - The Bogalusa Heart Study. J Chron Dis Ther Res, 4:169-191, 1980
Berenson GS, Voors AW, Webber LS: Hypertension in the Young - Measurement and Criteria. In: Phasic Pressor Mechanisms: Hypertension in the Young and the Old (Onesti G, Kim KE, Eds). New York: Grune and Stratton, p. 3-10, 1981
Voors AW, Berenson GS: Search for the Determinants of the Early Onset of Essential Hypertension. In: Phasic Pressor Mechanisms: Hypertension in the Young and the Old (Onesti G, Kim KE, Eds). New York: Grune and Stratton, p. 43-55, 1981
Berenson GS, Voors AW, Webber LS: Epidemiology in a Biracial Community in the Rural South of the United States. In: Phasic Pressor Mechanisms: Hypertension in the Young and Old (Onesti G, Kim KE, Eds). New York: Grune and Stratton, p. 183-190, 1981
Berenson GS, Voors AW, Webber LS: Blood Pressure in Children and Factors Predisposing to Hypertensive Disease in Adults. In: Paediatric Cardiology, Vol 4 (Godman MJ, Ed). Edinburgh: Churchill Livingstone, p. 591-600, 1981
Berenson GS, Webber LS, Voors AW: Diagnostic Challenge: Diagnosing Hypertension in Children. J Cardiovasc Med, 7:273-279, 1982
Wolf TM, Sklov MC, Hunter SM, Berenson GS: Factor Analytic Study of the Children's Nowicki-Strickland Locus of Control Scale. Educ Psychol Measure, 42:333-337, 1982
Voors AW, Sklov MC, Wolf TM, Hunter SM, Berenson GS: Cardiovascular Risk Factors in Children and Coronary Related Behavior. In: Promoting Adolescent Health: A Dialogue on Research and Practice (Coates T, Petersen A, Perry C, Eds). New York: Academic Press, p. 281-304, 1982
Frank GC, Berenson GS, Webber LS: Dietary Studies of Infants and Children. In: Promoting Adolescent Health: A Dialogue on Research and Practice (Coates T, Petersen A, Perry C, Eds). New York: Academic Press, p. 329-354, 1982
Frank GC, Webber LS, Berenson GS: Dietary Studies of 10-Year-Old Children in the Bogalusa Heart Study. In: Nutrition and Heart Disease (Naito HK, Ed). Jamaica, New York: Spectrum Publications, p. 91-110, 1982
Berenson GS, Voors AW, Frank GC, Webber LS: Studies of Blood Pressure and Dietary Sodium Intake in Children in Semirural Southern United States: The Bogalusa Heart Study. In: The Role of Salt in Cardiovascular Hypertension (Fregly MJ, Kare MR, Eds). New York: Academic Press, p. 49-62, 1982
Berenson GS: Racial Differences in Hypertension. In: Hypertension: Prevention, Diet, and Treatment in Infancy and Childhood, (Blumenthal S, Chairman and Ed). Proceedings from a Symposium Sponsored by Wyeth Laboratories, Bethesda, MD, May 25, 1983. Library of Congress No. 83-072205, p. 24-28, 1983
Berenson GS, Voors AW, Gard P, Newman WP III, Tracy RE: Clinical and Anatomic Correlates of Cardiovascular Disease in Children from the Bogalusa Heart Study. In: Atherosclerosis VI (Schettler FG, Gotto AM Jr, Middlehoff G, Habenicht AGR, Jurutke KR, Eds). New York: Springer-Verlag, p. 60-65, 1983
Srinivasan SR, Berenson GS: Serum Lipoproteins in Children and Methods for Study. In: CRC Handbook of Electrophoresis (Lipoproteins), Vol III (Lewis LA, Opplt JJ, Eds). Boca Raton, Florida: CRC Press, p. 185-203, 1983
Berenson GS, Webber LS, Frank GC, Farris RP: Management of the Mildly Hypertensive Youth: Can Adult Hypertensive Disease be Prevented? In NHLBI Workshop on Juvenile Hypertension (Loggie JMH, Horan MJ, Gruskin AB, Hohn AR, Dunbar JB, Havlik RJ, Eds). New York: Biomedical Information Corp., p. 387-407, 1984
Farris RP, Frank GC, Webber LS, Berenson GS: Quality Controls for Processing Dietary Data. J Diet Software, 1:3-4, 1984
Farris RP, Frank GC, Berenson GS: Halt the Salt. J Nutr Ed, 16:174a, 1984
Parker FC, Harsha DW, Farris RP, Webber LS, Frank GC, Berenson GS: Reducing the Risk of Cardiovascular Disease in Children. In: Self-Management of Chronic Disease (Holroyd K, Creer T, Eds). Orlando, FL: Academic Press, 1986
Berenson GS, Frank GC: Racial (Black-White) Differences in Blood Pressure in Children. In: Potassium in Cardiovascular and Renal Medicine: Arrhythmias, Myocardial Infarction, and Hypertension (Whelton PK, Whelton A, Walker WG, Eds). New York: Marcel Dekker, Inc., p. 365-380, 1986
Berenson GS, Wattigney W, Newman WP III, Tracy RE, Srinivasan SR, Webber LS: Relationship of Atherosclerosis and Risk Factors in Young Adults: Racial, Sex, and Anatomic Contrasts. The Bogalusa Heart Study. Symposium on Hypertension and Atherosclerosis CIC. Edizioni Internazionali, 1988
Cardiovascular Profile of 15,000 Children of School Age in Three Communities, 1971-1975. National Heart, Lung, and Blood Institute DHEW Publication No. (NIH) 78-1472, 1978
Berenson GS, McMahan CA, Voors AW, Webber LS, Srinivasan SR, Frank GC, Foster TA, Blonde CV: Cardiovascular Risk Factors in Children - The Early Natural History of Atherosclerosis and Essential Hypertension (editorial assistance: C. Andrews and H.E. Hester) New York, Oxford Univ. Press, p. 450, 1980
Berenson GS, Blonde CV, Webber LS (Eds): Monograph. Cardiovascular-Profile of Preschool Children in a Biracial Community (Bogalusa, Louisiana) - Bogalusa Heart Study, 1974. New Orleans: Louisiana State University Specialized Center of Research - Arteriosclerosis (SCOR-A). Library of Congress No. 81-52250, 1981
Berenson GS (Eds): Causation of Cardiovascular Risk Factors in Children: Perspectives on Cardiovascular Risk in Early Life. New York: Raven Press, p. 408, 1986
Frank GC, Webber LS, Farris RP, Berenson GS (Eds): Dietary Data Book: Quantifying Dietary Intakes of Infants, Children and Adolescents - The Bogalusa Heart Study, 1973-1983. From the Nutrition Core and Planning and Analysis Core Components of the National Research and Demonstration Center - Arteriosclerosis (NRDC-A). New Orleans: Louisiana State University Medical Center. Library of Congress Catalog Card No. 86-51215, 1986
Farris RP, Frank GC, Ditmarsen P, Berenson GS: Sodium Sense Curriculum: A Dietary Alteration Program Trial (ADAPT). New Orleans: LSU Medical Center. Library of Congress Catalog Card No. 86-82603, 1986
Hetzel BS, Berenson GS (Eds): Cardiovascular Risk Factors in Childhood: Epidemiology and Prevention. Amsterdam: Elsevier Science Publishers, B.V., 1987
Srinivasan SR, Webber LS, Berenson GS: Factors Influencing Serum Lipoprotein Levels in Children. In: Atherosclerosis: A Pediatric Perspective, (Subbiah MTR, Ed). CRC Press, Inc., 1989.

ClinicalTrials.gov Identifier: NCT00005129     History of Changes
Other Study ID Numbers: 908  1R01AG041200  1R01HD069587-01A1  1R01ES021724-01  2R01AG016592-12A1  R01HL121230 
Study First Received: May 25, 2000
Last Updated: September 24, 2015
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Cardiovascular Diseases
Heart Diseases
Atherosclerosis
Coronary Disease
Coronary Artery Disease
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases
Myocardial Ischemia

ClinicalTrials.gov processed this record on August 30, 2016