Topotecan in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer
|ClinicalTrials.gov Identifier: NCT00005029|
Recruitment Status : Terminated
First Posted : July 19, 2004
Last Update Posted : April 11, 2013
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of topotecan in treating patients who have recurrent ovarian epithelial or primary peritoneal cancer.
|Condition or disease||Intervention/treatment||Phase|
|Ovarian Cancer Primary Peritoneal Cavity Cancer||Drug: topotecan hydrochloride||Phase 2|
OBJECTIVES: I. Determine the antitumor activity of topotecan in patients with recurrent platinum sensitive ovarian epithelial or primary peritoneal cancer. II. Determine the nature and degree of toxicity of this treatment regimen in these patients.
OUTLINE: Patients receive topotecan IV over 30 minutes on days 1-3. Treatment continues every 3 weeks in the absence of disease progression or unacceptable toxicity. Patients are followed every 3 months for 2 years and then every 6 months for 3 years.
PROJECTED ACCRUAL: A total of 22-60 patients will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Phase II Evaluation of Three-Day Topotecan (NSC 609699) in Recurrent Platinum-Sensitive Ovarian or Primary Peritoneal Cancer|
|Study Start Date :||February 2000|
|Estimated Primary Completion Date :||January 2004|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00005029
Show 74 Study Locations
|Study Chair:||David S. Miller, MD||Simmons Cancer Center|