Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups
|ClinicalTrials.gov Identifier: NCT00004781|
Recruitment Status : Completed
First Posted : February 25, 2000
Last Update Posted : June 24, 2005
OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men, male intravenous drug users, and female intravenous drug users.
II. Evaluate the immune and inflammatory response to periodontal and other microbial pathogens.
III. Evaluate the bacterial species infecting the oral cavity in patients in these risk groups.
|Condition or disease|
|HIV Infections Candidiasis, Oral|
Patients undergo a periodontal assessment every 6 months until medically unable to continue. The oral/dental exam includes saliva and gingival crevicular fluid analysis and, as indicated, oral photographs.
|Study Type :||Observational|
|Estimated Enrollment :||250 participants|
|Study Start Date :||September 1989|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004781
|Study Chair:||Ira B. Lamster||Columbia University|