Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma
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|ClinicalTrials.gov Identifier: NCT00002898|
Recruitment Status : Completed
First Posted : January 27, 2003
Last Update Posted : December 4, 2013
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery and/or radiation therapy may kill more tumor cells.
PURPOSE: This randomized phase III trial is studying surgery followed by different regimens of combination chemotherapy given together with radiation therapy and/or additional surgery to compare how well they work in treating patients with soft tissue sarcoma.
|Condition or disease||Intervention/treatment||Phase|
|Childhood Malignant Fibrous Histiocytoma of Bone Sarcoma||Biological: dactinomycin Drug: carboplatin Drug: cyclophosphamide Drug: epirubicin hydrochloride Drug: etoposide Drug: ifosfamide Drug: vincristine sulfate Procedure: adjuvant therapy Procedure: conventional surgery Procedure: neoadjuvant therapy Radiation: brachytherapy Radiation: radiation therapy||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||400 participants|
|Official Title:||MMT 95 Study For Rhabdomyosarcoma and Other Malignant Soft Tissue Tumors of Childhood|
|Study Start Date :||January 1995|
|Actual Study Completion Date :||December 2009|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00002898
|Institute of Child Health|
|Bristol, England, United Kingdom, BS2 8AE|
|Study Chair:||M. C. G. Stevens, MD||Institute of Child Health at University of Bristol|