Studies on Tumors of the Thyroid
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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00001160 |
Recruitment Status :
Recruiting
First Posted : November 4, 1999
Last Update Posted : June 28, 2022
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Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer.
The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid nodules and thyroid cancer. Many of the test performed are in the context of standard medical care that is offered to all patients with thyroid nodules or thyroid cancer. Other tests are performed for research purposes. In addition, blood and tissue samples will be taken for research and genetic studies.
Condition or disease |
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Hurthle Cell Thyroid Cancer Tall Cell Variant Thyroid Cancer Follicular Thyroid Cancer Thyroid Cancer Papillary Thyroid Cancer |
Study Type : | Observational |
Estimated Enrollment : | 2500 participants |
Observational Model: | Case-Only |
Time Perspective: | Prospective |
Official Title: | Studies on Thyroid Nodules and Thyroid Cancer |
Actual Study Start Date : | June 1, 1977 |

Group/Cohort |
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thyroid cancer
Patients with thyroid cancer
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thyroid nodules
Patients with thyroid nodules
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- Evaluation of thyroid cancer [ Time Frame: As clinically indicated ]Blood draws, CT and other scans, physical exams, surgery (if applicable), thyroid biopsy (if applicable).
- Evaluation of thyroid disorders [ Time Frame: As clinically indicated ]blood draws, CT and other scans, physical exam.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 6 Months and older (Child, Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
- INCLUSION CRITERIA:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Male or female, adults or children >= 6 months+.
- Patients with known or suspected thyroid nodules and/or thyroid cancer.
- At risk family members of patients who have a genetic susceptibility to developing thyroid cancer.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
1. Serious underlying medical conditions that restrict diagnostic testing or therapy such as renal failure, congestive cardiac failure or active coexisting non-thyroid carcinoma requiring intervention before thyroid cancer is addressed.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001160
Contact: Padmasree Veeraraghavan, N.P. | (301) 451-7710 | padmasree.veeraraghavan@nih.gov | |
Contact: Joanna Klubo-Gwiezdzinska, M.D. | (301) 496-5052 | joanna.klubo-gwiezdzinska@nih.gov |
United States, Maryland | |
National Institutes of Health Clinical Center | Recruiting |
Bethesda, Maryland, United States, 20892 | |
Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY dial 711 ccopr@nih.gov |
Principal Investigator: | Joanna Klubo-Gwiezdzinska, M.D. | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Publications:
Responsible Party: | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
ClinicalTrials.gov Identifier: | NCT00001160 |
Other Study ID Numbers: |
770096 77-DK-0096 |
First Posted: | November 4, 1999 Key Record Dates |
Last Update Posted: | June 28, 2022 |
Last Verified: | June 10, 2022 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | Undecided |
Plan Description: | .Subject level data will be shared upon request after appropriate collaboration agreements are in place. |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
Thyroid Fine Needle Biopsy Radioiodine Dosimetry Natural History |
Thyroid Neoplasms Thyroid Cancer, Papillary Adenocarcinoma, Follicular Thyroid Diseases Endocrine System Diseases Endocrine Gland Neoplasms Neoplasms by Site |
Neoplasms Head and Neck Neoplasms Adenocarcinoma, Papillary Adenocarcinoma Carcinoma Neoplasms, Glandular and Epithelial Neoplasms by Histologic Type |