9 studies found for:    pancreatic,cancer,PARP
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Rank Status Study
1 Completed Study to Assess the Safety & Tolerability of a PARP Inhibitor in Combination With Gemcitabine in Pancreatic Cancer
Condition: Pancreatic Neoplasms
Interventions: Drug: KU-0059436 (AZD2281)(PARP inhibitor);   Drug: Gemcitabine
2 Completed Flavopiridol Plus Radiation Therapy Followed By Gemcitabine Hydrochloride in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer
Conditions: Adenocarcinoma of the Pancreas;   Recurrent Pancreatic Cancer;   Stage II Pancreatic Cancer;   Stage III Pancreatic Cancer;   Stage IV Pancreatic Cancer
Interventions: Drug: alvocidib;   Drug: gemcitabine hydrochloride;   Radiation: 3-dimensional conformal radiation therapy;   Other: laboratory biomarker analysis
3 Recruiting Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Patients With Locally Advanced or Metastatic Pancreatic Cancer
Conditions: BRCA1 Mutation Carrier;   BRCA2 Mutation Carrier;   Pancreatic Adenocarcinoma;   Recurrent Pancreatic Carcinoma;   Stage III Pancreatic Cancer;   Stage IV Pancreatic Cancer
Interventions: Drug: Cisplatin;   Drug: Gemcitabine Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Veliparib
4 Recruiting A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation
Conditions: Pancreatic Cancer;   Pancreatic Ductal Adenocarcinoma
Intervention: Drug: Rucaparib
5 Recruiting ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic Cancer
Condition: Metastatic Pancreatic Cancer
Intervention: Drug: Veliparib and 5-FU and Oxaliplatin and Leucovorin
6 Active, not recruiting Study of BMN 673, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors
Conditions: Advanced or Recurrent Solid Tumors;   Breast Neoplasms;   Ovarian Cancer, Epithelial;   Ewing Sarcoma;   Small Cell Lung Carcinoma;   Prostate Cancer;   Pancreas Cancer
Intervention: Drug: BMN 673
7 Active, not recruiting Veliparib in Treating Patients With Malignant Solid Tumors That Did Not Respond to Previous Therapy
Conditions: Adult Solid Neoplasm;   BRCA1 Mutation Carrier;   BRCA2 Mutation Carrier;   Estrogen Receptor Negative;   HER2/Neu Negative;   Hereditary Breast and Ovarian Cancer Syndrome;   Male Breast Carcinoma;   Progesterone Receptor Negative;   Recurrent Breast Carcinoma;   Recurrent Fallopian Tube Carcinoma;   Recurrent Ovarian Carcinoma;   Recurrent Pancreatic Carcinoma;   Recurrent Primary Peritoneal Carcinoma;   Recurrent Prostate Carcinoma;   Triple-Negative Breast Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Veliparib
8 Recruiting Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations
Conditions: Advanced Ovarian Cancer;   Primary Peritoneal Cancer;   Advanced Breast Cancer;   Advanced Solid Tumors
Intervention: Drug: BMN 673
9 Active, not recruiting Open Label Study to Assess Efficacy and Safety of Olaparib in Confirmed Genetic BRCA1 or BRCA2 Mutation Pats
Conditions: Ovarian;   Breast;   Prostate;   Pancreatic;   Advanced Tumours
Intervention: Drug: olaparib

Indicates status has not been verified in more than two years