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27 studies found for:    Dravet Syndrome
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Rank Status Study
1 No longer available Stiripentol in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: stiripentol
2 Available Compassionate Use of Stiripentol in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Stiripentol
3 Available Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Stiripentol
4 Completed Verapamil as Therapy for Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Verapamil
5 Terminated Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Clobazam
6 Withdrawn Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: Clobazam;   Drug: Placebo
7 Enrolling by invitation An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: ZX008 (Fenfluramine Hydrochloride)
8 Available Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalopathies
Conditions: Dravet Syndrome;   Epileptic Encephalopathies Associated With SCN1A Mutations
Intervention: Drug: Stiripentol
9 Recruiting A Two-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥2 Years Old and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: ZX008 - 0.2 mg/kg/day;   Drug: ZX008 - 0.4 mg/kg/day;   Drug: ZX008 - 30 mg/kg/day maximum dose;   Drug: Matching Placebo
10 Recruiting A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) as an Adjunctive Therapy in Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: ZX008 - 0.8 mg/kg/day;   Drug: ZX008 - 0.2 mg/kg/day;   Drug: Placebo
11 Not yet recruiting Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: Cannabidiol Oral Solution;   Drug: Placebo Solution
12 Recruiting Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Device: measure of neuronal excitability
13 Completed Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
14 Recruiting GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo Control
15 Completed A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
16 Recruiting A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome
Conditions: Dravet Syndrome;   Seizure Disorder
Interventions: Drug: ZX008 (Fenfluramine Hydrochloride);   Drug: Matching Placebo
17 Recruiting Cardiac Arrhythmias in Dravet Syndrome
Condition: Epilepsy
Intervention:
18 Recruiting Genetic Analysis Between Charlotte's Web Responders Versus Non- Responders in a Dravet Population
Condition: Dravet Syndrome
Intervention:
19 Recruiting Ataluren for Nonsense Mutation in CDKL5 and Dravet Syndrome
Condition: Epilepsy
Interventions: Drug: ataluren;   Drug: Placebo
20 Not yet recruiting The Pharmacokinetics of Cannabidiol (CBD) and Its Effects in Children With Severe Epilepsy
Conditions: Dravet Syndrome;   Lennox Gastaut Syndrome
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.