National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health Clinical Center (CC)
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Safety: evaluate local toxicity & systemic reactions to vaccination. Severe reactions to vaccine (i.e. lower respiratory or GI tract disease) or systemic symptoms related to vaccine.
Immunogenicity: Data collected for: H5-specific antibody, mucosal humoral, & cellular immune response; vaccine virus shedding & genetic stability; transmission of virus to household/intimate contacts.
18 Years to 49 Years (Adult)
September 14, 2011
December 31, 2018
January 1, 2019
September 30, 2011
February 14, 2018
National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States
† Study has passed its completion date and status has not been verified in more than two years.