To determine whether wide excision of the primary with intraoperative lymphatic mapping (LM) followed by selective lymphadenectomy will effectively prolong overall survival compared to wide excision of the primary melanoma alone.
Disease-free survival; Incidence, timing, and anatomic distribution of distant metastases; Morbidity of procedures; Significance of TA90 levels; Incidence of Sentinel Node Metastases (biopsy) vs clinical metastases (observation); Accuracy of LM
18 Years to 75 Years (Adult, Senior)
MSLT-1 NIH P01 CA029605
January 12, 2006
September 2, 2015
† Study has passed its completion date and status has not been verified in more than two years.