University of Colorado Denver School of Medicine Barbara Davis Center
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Supportive Care
To demonstrate a decrease in post-prandial glucagon release as assessed by glucagon area under the curve (AUC) for 3 hours during 4 hour meal tolerance tests
Secondary objectives: 1. To demonstrate a 0.3% decrease in A1c in patients with type 1 diabetes after 16 weeks of treatment with sitagliptin. 2. To evaluate changes in total, basal and bolus insulin dose while on sitagliptin.
18 Years to 70 Years (Adult, Senior)
October 25, 2010
May 21, 2014
University of Colorado/Barbara Davis Center for Diabetes Aurora, Colorado, United States
† Study has passed its completion date and status has not been verified in more than two years.