PD/PK: Dose response of SCH 527123 on ozone-induced sputum neutrophilia in healthy subjects (Part 1) and subjects with COPD (Part 2), measured by placebo-adjusted percent change in sputum neutrophil counts and absolute sputum neutrophil counts.
18 Years to 65 Years (Adult)
February 12, 2010
March 26, 2015
† Study has passed its completion date and status has not been verified in more than two years.