| 1 |
NCT03526107 |
Active, not recruiting |
Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines |
|
- Other: CF Control
- Other: CF-Theobromine
- Other: CF-Caffeine
|
Interventional
|
Not Applicable |
- University of California, Davis
- Mars, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Basic Science
|
- Flavanol metabolites in plasma
- Flavanol metabolites in urine
- Methylxanthines in plasma
- Methylxanthines in urine
|
10 |
Male |
25 Years to 60 Years (Adult) |
NCT03526107 |
429275-T |
|
February 16, 2017 |
December 23, 2018 |
December 23, 2018 |
May 16, 2018 |
May 28, 2018 |
|
- Ragle Human Nutrition Research Center, Department of Nutrition at UC Davis
Davis, California, United States - UC Davis
Davis, California, United States
|
|
| 2 |
NCT03526094 |
Active, not recruiting |
Flavanol Absorption, Metabolism and Excretion From Fruit-based Drinks and Other Food Matrixes |
|
- Other: Flavanols-capsules
- Other: Flavanol-banana blend
- Other: Flavanol-high protein drink
- (and 7 more...)
|
Interventional
|
Not Applicable |
- University of California, Davis
- Mars, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Investigator)
- Primary Purpose: Basic Science
|
- Flavanol metabolites in plasma
- Flavanol metabolites in urine
|
23 |
Male |
25 Years to 60 Years (Adult) |
NCT03526094 |
429275-D |
|
May 5, 2016 |
December 28, 2018 |
December 28, 2018 |
May 16, 2018 |
May 28, 2018 |
|
- Ragle Human Nutrition Research Center, Department of Nutrition at UC Davis
Davis, California, United States - UC Davis
Davis, California, United States
|
|
| 3 |
NCT03526081 |
Active, not recruiting |
Absorption, Metabolism and Excretion of Apigenin and Apigenin Glycosides |
|
- Other: Chamomile Tea
- Other: Parsley based drink
- Other: Parsley Yogurt
- (and 2 more...)
|
Interventional
|
Not Applicable |
- University of California, Davis
- Mars, Inc.
|
Other / Industry |
- Allocation: Non-Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Investigator)
- Primary Purpose: Basic Science
|
- Flavone metabolites in plasma
- Flavone metabolites in urine
|
17 |
Male |
25 Years to 60 Years (Adult) |
NCT03526081 |
429275-10 |
|
January 20, 2015 |
December 31, 2018 |
December 31, 2018 |
May 16, 2018 |
May 28, 2018 |
|
- Ragle Human Nutrition Research Center, Department of Nutrition at UC Davis
Davis, California, United States - UC Davis
Davis, California, United States
|
|
| 4 |
NCT03201822 |
Completed |
Intake-dependent Effect of Cocoa Flavanol Absorption, Metabolism and Excretion in Humans |
|
- Other: 100 mg of Cocoa Flavanols/70 kg BW
- Other: 200 mg of Cocoa Flavanols/70 kg BW
- Other: 400 mg of Cocoa Flavanols/70 kg BW
- Other: 1000 mg of Cocoa Flavanols/70 kg BW
|
Interventional
|
Not Applicable |
- University of California, Davis
- Mars, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Basic Science
|
- Change in levels of gut microbiome derived metabolites in urine
- Change in levels of gut microbiome derived metabolites in plasma
- Change in levels of structurally related epicatechin metabolites in urine
- (and 12 more...)
|
14 |
Male |
25 Years to 40 Years (Adult) |
NCT03201822 |
429275 |
|
April 1, 2013 |
May 25, 2013 |
May 25, 2013 |
June 28, 2017 |
June 28, 2017 |
|
- UC Davis
Davis, California, United States
|
|
| 5 |
NCT03194620 |
Completed |
Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans |
|
- Other: Thearubigins
- Other: Theaflavins
- Other: Procyanidin Dimer B2 (DB2)
- (and 5 more...)
|
Interventional
|
Not Applicable |
- University of California, Davis
- Mars, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Basic Science
|
- Changes in the concentration of flavanol metabolites in urine.
- Changes in the concentration of flavanol metabolites in plasma
|
12 |
Male |
25 Years to 60 Years (Adult) |
NCT03194620 |
907244 |
|
August 2016 |
January 12, 2017 |
January 12, 2017 |
June 21, 2017 |
November 6, 2017 |
|
- UC Davis
Davis, California, United States
|
|
| 6 |
NCT01496235 |
Terminated |
Effect of Cocoa Consumption in Cardiovascular and Immune Parameters |
|
- Dietary Supplement: Dark chocolate
- Dietary Supplement: White chocolate
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in diastolic blood pressure
- Change in systolic blood pressure
- Change in total cholesterol
- (and 8 more...)
|
69 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01496235 |
Cacao I |
|
July 2009 |
July 2011 |
July 2011 |
December 21, 2011 |
December 21, 2011 |
|
- Sede Investigaciones Universitarias, Universidad de Antioquia
Medellín, Antioquia, Colombia
|
|
| 7 |
NCT01276951 |
Completed |
Controlled Clinical Trial to Determine the Effective Dose of Cocoa in Lowering Blood Pressure |
|
- Dietary Supplement: Delivery and return of chocolate
- Procedure: Determination of blood pressure
- Procedure: Anthropometric Measurements
- (and 3 more...)
|
Interventional
|
Not Applicable |
- Universidad de Antioquia
- Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Change on blood pressure in patients with stage I-II hypertension, after consumption of different doses of cocoa.
- Change in the oxidation of low density lipoproteins after cocoa consumption, in patients with stage I-II hypertension.
- Change in the production of inflammatory molecules derived from peripheral blood mononuclear cells of patients with arterial hypertension stage I-II, after cocoa consumption.
- Change in platelet aggregation after cocoa consumption, in patients with essential arterial hypertension stage I-II.
|
125 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01276951 |
Cacao III |
|
December 2008 |
September 2011 |
September 2011 |
January 14, 2011 |
January 24, 2017 |
|
- Sede Investigaciones Universitarias, Universidad de Antioquia
Medellín, Antioquia, Colombia
|
|
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