To replicate and extend our previous behavioral findings of an interaction between estrogen therapy (ET) and tryptophan depletion on verbal memory in a group of early menopausal women randomized to receive ET.
To evaluate the extent to which effects of ET (estrogen therapy) and TRP-D (tryptophan depletion) on verbal working memory are mediated through the dorsolateral prefrontal cortex.
48 Years to 60 Years (Adult)
March 4, 2010
September 23, 2010
September 18, 2017
Penn Center for Women's Behavioral Wellness, University of Pennsylvania Philadelphia, Pennsylvania, United States
† Study has passed its completion date and status has not been verified in more than two years.