| 1 |
NCT01330589 |
Withdrawn |
Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort |
|
- Drug: Placebo
- Drug: St. Johns Wort
|
Interventional |
Not Applicable |
- Lancaster General Hospital
- H. G. Barsumian Memorial Fund
- Louise von Hess Medical Research Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Mean platelet reactivity (as measured in platelet reactivity units) on day 7 and day 21
|
0 |
All |
18 Years and older (Adult, Senior) |
NCT01330589 |
2010-56-LGH |
INDUCE-it |
April 2011 |
March 2015 |
March 2015 |
April 7, 2011 |
October 5, 2017 |
|
- Lancaster General Hospital
Lancaster, Pennsylvania, United States
|
| 2 |
NCT00140465 |
Completed |
75 or 150 mg Clopidogrel Maintenance Doses Following PCI (ISAR-CHOICE-2) |
|
|
Interventional |
Phase 4 |
- Deutsches Herzzentrum Muenchen
- Technische Universität München
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Maximal ADP(5µmol/l)-induced platelet aggregation 30 days after the intervention
- Maximal ADP(20µmol/l)-induced platelet aggregation 30 days after the intervention
- P2Y12 inhibition measured by point-of-care test
|
60 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT00140465 |
GE IDE No. A00803 |
|
October 2004 |
|
July 2005 |
September 1, 2005 |
November 14, 2007 |
|
- Deutsches Herzzentrum Muenchen
Munich, Germany
|
| 3 |
NCT02748330 |
Recruiting |
Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary Intervention |
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
|
- Drug: Ticagrelor
- Drug: Clopidogrel
- Drug: Aspirin
|
Interventional |
Phase 4 |
- Peking Union Medical College Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- P2Y12 reaction unit (PRU)
- P2Y12 reaction unit (PRU) (before)
- Percent inhibition (% Inhibition)
- (and 6 more...)
|
40 |
All |
18 Years and older (Adult, Senior) |
NCT02748330 |
HS-873
ESR-14-10403 |
PLATIDE-PCI |
June 2016 |
March 2018 |
April 2018 |
April 22, 2016 |
December 21, 2017 |
|
- Peking Union Medical College Hospital
Beijing, Beijing, China
|
| 4 |
NCT00735280 |
Completed |
Reduced Dose of Unfractionated Heparin in Patients Undergoing PCI |
|
- Drug: unfractionated heparin
|
Interventional |
Phase 4 |
- Deutsches Herzzentrum Muenchen
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The primary outcome measure will be a composite of death, MI, urgent TVR after 30 days or in hospital bleeding (quadruple endpoint, "net clinical benefit").
- Composite of death, MI or urgent TVR (Triple endpoint to assess ischemic complications)
- Composite of death, MI or TVR
|
2505 |
All |
18 Years and older (Adult, Senior) |
NCT00735280 |
GE IDE No. A01408 |
ISAR-REACT-3A |
August 2008 |
March 2010 |
March 2011 |
August 14, 2008 |
January 5, 2012 |
|
- Herz-Zentrum
Bad Krozingen, Germany - Deutsches Herzzentrum München
München, Germany - Klinikum rechts der Isar der Technischen Universität München
München, Germany
|
| 5 |
NCT00378612 |
Completed |
ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial |
|
- Device: Cypher sirolimus eluting coronary stent
|
Interventional |
Phase 3 |
- Sunil Rao
- Cordis Corporation
- Duke University
|
Other / Industry |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Angiographic binary restenosis (>=50% diameter stenosis) in TCO treated/working length compared with restenosis outcomes in the Total Occlusion Study of Canada (TOSCA)
- Angiographic binary in-segment restenosis (>= 50% diameter stenosis) rate at 6 months post-procedure
- Angiographic binary in-stent restenosis (>= 50% diameter stenosis) rate at 6 months post-procedure
- (and 11 more...)
|
200 |
All |
18 Years and older (Adult, Senior) |
NCT00378612 |
Pro00007965
1525004 |
|
June 2005 |
April 2007 |
September 2012 |
September 20, 2006 |
September 12, 2014 |
|
- Green Hospital of Scripps Health
La Jolla, California, United States - Scripps Memorial Hospital-La Jolla
La Jolla, California, United States - Washington Hospital Center
Washington, District of Columbia, United States - (and 13 more...)
|
| 6 |
NCT00149591 |
Unknown † |
The Viability-Guided Angioplasty After Acute Myocardial Infarction-Trial (The VIAMI-Trial) |
- Myocardial Infarction
- Coronary Artery Disease
|
- Procedure: coronary balloon-angioplasty with stenting
|
Interventional |
Not Applicable |
- Netherlands Heart Foundation
- The Interuniversity Cardiology Institute of the Netherlands
- Eli Lilly and Company
- (and 2 more...)
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Death
- Recurrent myocardial infarction
- Unstable angina for which hospital admission required
- (and 6 more...)
|
300 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT00149591 |
2000B026
H4S-UT-O017 |
|
April 2001 |
|
January 2007 |
September 8, 2005 |
September 5, 2008 |
|
- Medical Center Alkmaar (MCA)
Alkmaar, Netherlands - Sint LucasAndreas Hospital
Amsterdam, Netherlands - VU University medical center
Amsterdam, Netherlands - (and 9 more...)
|
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