National Institute of Neurological Disorders and Stroke (NINDS)
National Institutes of Health Clinical Center (CC)
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Assess the safety and tolerability of 4 different dose levels of AAV2-GDNF
Obtain preliminary data regarding the potential for clinical responses of the 4 dose levels tested by assessing the magnitude and variability of any treatment effects (via clinical, laboratory and neuroimaging studies).
18 Years and older (Adult, Senior)
May 31, 2012
January 1, 2025
December 31, 2027
June 18, 2012
November 24, 2017
National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States
† Study has passed its completion date and status has not been verified in more than two years.