20 studies found for:    11794169 [PUBMED-IDS]
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Rank Status Study
1 Enrolling by invitation Critical Care Excellence in Sepsis and Trauma
Conditions: Sepsis;   Trauma
Intervention:
2 Unknown  Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study
Conditions: Paediatric Sepsis;   Pediatric Sepsis
Intervention: Drug: hydrocortisone
3 Completed Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Condition: Acute Lung Injury
Interventions: Drug: Diuresis (furosemide) part I;   Other: Fluid Bolus (crystalloid or albumin);   Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine);   Drug: Dobutamine;   Other: Concentrate all drips and nutrition;   Drug: Diuresis (furosemide) part II;   Procedure: Dialysis
4 Completed BaSES Trial: Basel Starch Evaluation in Sepsis
Conditions: Sepsis;   Severe Sepsis;   Septic Shock
Intervention: Drug: hydroxy-ethyl starch (MW 130; 0.4) vs. normal saline
5 Terminated
Has Results
Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock
Conditions: Severe Sepsis;   Septic Shock
Interventions: Device: Esophageal Doppler monitoring - CardioQ, Deltex Inc;   Device: Central line with CVP and continuous ScvO2 monitoring
6 Unknown  Reducing Elevated Heart Rate in Patients With Multiple Organ Dysfunction Syndrome (MODS) by Ivabradine
Condition: Multiple Organ Dysfunction Syndrome
Intervention: Drug: ivabradine
7 Active, not recruiting Protocolized Care for Early Septic Shock
Conditions: Sepsis;   Severe Sepsis;   Septic Shock
Interventions: Procedure: Early Goal Directed Therapy (EGDT);   Procedure: Protocolized Standard Care (PSC);   Procedure: Usual Care (UC)
8 Unknown  Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit
Condition: Blood Lactate Analysis
Intervention: Procedure: Blood Lactate Analysis
9 Unknown  Lactate Clearance According to the Presence of Hepatic Dysfunction
Conditions: Sepsis;   Liver Failure
Intervention:
10 Not yet recruiting Statistical Analysis Plan for an Individual Patient Data Meta-analysis of Three, International Trials Comparing Protocolised With Usual Resuscitation in Patients Presenting to the Emergency Department With Severe Sepsis and Septic Shock
Condition: Severe Sepsis and Septic Shock
Intervention:
11 Recruiting Comparing USCOM and Echocardiographic Hemodynamic Measurements in Children (CUE Study)
Conditions: Hemodynamically Stable;   Critical Illness
Intervention: Device: Ultrasound Cardiac Output Monitor and 2 D-Echo
12 Completed Early Lactate-Directed Therapy in the Intensive Care Unit (ICU)
Conditions: Tissue Hypoxia;   Hyperlactatemia
Intervention: Procedure: Early lactate-directed therapy
13 Not yet recruiting PPV to Guide Fluid Management in the PICU
Conditions: Sepsis;   Systemic Inflammatory Response Syndrome
Intervention: Device: Automated Pulse Pressure Variation
14 Unknown  Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)
Condition: Shock
Interventions: Device: Cheetah NICOM®  PLRT;   Device: USCOM ® (Ultrasound Cardiac Output Monitor);   Device: Inferior Vena Cava (IVC) Ultrasound Collapsibility;   Behavioral: CURVES Questionnaire;   Biological: Lactate Clearance;   Biological: 500ml Normal Saline Bolus;   Biological: Clinician Discretion Intravenous Fluid Management
15 Completed
Has Results
Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
Condition: Sepsis
Interventions: Drug: Inhaled nitric oxide;   Other: Sham inhaled nitric oxide
16 Not yet recruiting Oxygen Consumption in Critical Illness
Condition: Critical Illness
Intervention:
17 Recruiting Echo vs. EGDT in Severe Sepsis and Septic Shock
Conditions: Severe Sepsis;   Septic Shock
Interventions: Other: Echo guided fluid resuscitation;   Other: EGDT fluid resuscitation
18 Unknown  Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests
Conditions: Sepsis;   Septicemia;   Sepsis Syndrome;   Shock, Septic;   Community Acquired Pneumonia
Intervention:
19 Completed Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring
Conditions: Severe Sepsis;   Septic Shock
Intervention: Procedure: Central venous oxygen saturation continuous monitoring
20 Withdrawn Restricted Fluid Regimen in Open Abdominal Bowel Surgery
Condition: Bowel Surgery
Interventions: Other: intraoperative fluid management;   Other: fluid restriction

Indicates status has not been verified in more than two years