Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Prevention
To determine whether patients given oral Lactobacillus GG will have a smaller increase in the density of pathogenic bacterial in cultures from oral swabs, nasogastric aspirates, and minimally invasive bronchoalveolar lavage samples.
To assess whether administration of Lactobacillus GG to intubated patients reduces clinically diagnosed VAP,reduces microbiologically diagnosed VAP, affects mortality and duration of mechanical ventilation, and total antibiotic consumption.
19 Years and older (Adult, Senior)
February 13, 2008
March 18, 2010
Creighton University Medical Center Omaha, Nebraska, United States
† Study has passed its completion date and status has not been verified in more than two years.