471 studies found for:    Open Studies | antidepressants
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Rank Status Study
1 Recruiting Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients
Condition: Depression
Interventions: Drug: antidepressant response;   Drug: antidepressant non-response
2 Not yet recruiting A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
Condition: Treatment-resistant Depression
Interventions: Drug: Esketamine;   Drug: Placebo;   Drug: Duloxetine (Oral Antidepressant);   Drug: Escitalopram (Oral antidepressant);   Drug: Sertraline (Oral Antidepressant);   Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant)
3 Not yet recruiting A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression
Condition: Treatment-resistant Depression
Interventions: Drug: Esketamine;   Drug: Placebo;   Drug: Duloxetine (Oral Antidepressant);   Drug: Escitalopram (Oral Antidepressant);   Drug: Sertraline (Oral Antidepressant);   Drug: Venlafaxine Extended Release (XR) (New Antidepressant)
4 Not yet recruiting A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
Condition: Treatment-resistant Depression
Interventions: Drug: Esketamine;   Drug: Placebo;   Drug: Duloxetine (Oral Antidepressant);   Drug: Escitalopram (Oral antidepressant);   Drug: Sertraline (Oral Antidepressant);   Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant)
5 Unknown  Interpersonal Psychotherapy for Treatment Resistant Depression
Condition: Treatment Resistant Depression
Interventions: Other: IPT+ antidepressant drugs;   Drug: fluoxetine;   Drug: sertraline;   Drug: paroxetine;   Drug: Citalopram;   Drug: escitalopram;   Drug: fluvoxamine;   Drug: Venlafaxine;   Drug: Duloxetine;   Drug: Bupropion;   Drug: Lithium;   Drug: Risperidone;   Drug: tranylcypromine;   Drug: Imipramine;   Drug: amitriptyline;   Drug: Clomipramine;   Drug: nortriptyline;   Drug: trazodone;   Drug: Mirtazapine;   Drug: sulpiride
6 Recruiting Predictors of Antidepressant Response
Condition: Depression
Interventions: Other: Placebo;   Drug: Citalopram, or other antidepressant as clinically indicated
7 Not yet recruiting Evaluation of the Efficacy of Serotoninergic Antidepressants in Bulimia Nervosa, According to Brain Serotonin Profile Determined by Positron Emission Tomography With [18F] MPPF.
Condition: Bulimia Nervosa
Interventions: Drug: Antidepressants;   Drug: Positron Emission Tomography (PET)
8 Recruiting Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
Conditions: Major Depressive Disorder;   Dysthymic Disorder;   Depressive Disorder, NOS
Intervention: Drug: Antidepressant Medication
9 Recruiting Patient Decision Aid for Antidepressant Use in Pregnancy
Conditions: Pregnancy;   Depression
Interventions: Behavioral: Electronic Patient Decision Aid;   Behavioral: Standard Resource Sheet
10 Unknown  Pharmacotherapy and Psychotherapy for MDD After Remission on Psychology and Neuroimaging
Condition: Depressive Disorder
Interventions: Behavioral: medicine combined CBT;   Drug: medicine
11 Unknown  Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression
Condition: Major Depression
Interventions: Drug: antidepressant medications, flexible drug choice;   Behavioral: CBT, Psychodynamic or Supportive Psychotherapy
12 Recruiting Magnetic Resonance Imaging Study of Cognitive-Behavior Therapy for Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: SSRI antidepressants;   Behavioral: Cognitive-Behavior Therapy
13 Not yet recruiting eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients
Conditions: Depression;   Major Depressive Disorder;   Dysthymic Disorder;   Depressive Symptoms;   Cardiovascular Diseases;   Heart Diseases;   Coronary Artery Disease;   Stroke
Interventions: Behavioral: Beating the Blues (BtB);   Behavioral: Problem Solving Treatment in Primary Care (PST-PC);   Drug: Antidepressant Medications;   Other: Usual Care
14 Recruiting Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications
Conditions: Depressive Disorder;   Lactation
Intervention: Drug: SSRI/SNRI
15 Recruiting Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.
Condition: Bipolar I Disorder
Interventions: Drug: Escitalopram;   Drug: Wellbutrin XL
16 Recruiting Development of Pharmacogenomic Method to Predict Antidepressant Responsiveness
Conditions: Depression;   Antidepressant Drug Adverse Reaction
Interventions: Drug: SSRI treated group;   Drug: non-SSRI treated group
17 Recruiting Pharmacogenomic Study to Predict Antidepressant Responsiveness in Depressed Patients
Conditions: Depression;   Adverse Reaction to Drug
Interventions: Drug: SSRI treated group;   Drug: non-SSRI treated group
18 Recruiting Effects of Treatment on Decision-making in Major Depression
Conditions: Major Depressive Disorder;   Healthy Controls
Intervention: Drug: Antidepressant
19 Recruiting Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction?
Conditions: Sexual Dysfunction;   Major Depressive Disorder
Interventions: Drug: Vilazodone;   Drug: Sertraline
20 Recruiting A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND}
Conditions: Depression;   End Stage Renal Disease
Interventions: Behavioral: Engagement Interview;   Behavioral: Cognitive Behavioral Therapy;   Drug: Antidepressant Drug Therapy

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Indicates status has not been verified in more than two years