23 studies found for:    Open Studies | "Shy-Drager Syndrome"
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Rank Status Study
1 Recruiting PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)
Conditions: Multiple System Atrophy - Parkinsonian Subtype (MSA-P);   Multiple System Atrophy - Cerebellar Subtype (MSA-C)
Intervention:
2 Recruiting Oligomeric Alpha-synuclein in Multiple System Atrophy
Condition: Multiple System Atrophy (MSA)
Intervention:
3 Recruiting Cognitive and Behavioral Dysexecutive Syndrome in Multiple System Atrophy
Condition: Multiple System Atrophy
Interventions: Other: Clinical evaluation;   Other: neuropsychological battery test;   Other: MRI;   Other: Actigraphy
4 Recruiting Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.
Conditions: Parkinson Disease;   Multiple System Atrophy
Intervention: Drug: Intranasal Insulin
5 Recruiting Water and Sudafed in Autonomic Failure
Conditions: Shy-Drager Syndrome;   Multiple System Atrophy
Interventions: Drug: Pseudoephedrine + 480 ml water;   Drug: Pseudoephedrine + 50 ml water;   Other: Placebo + 480 ml water (optional);   Other: Placebo + 50 ml water (optional)
6 Recruiting Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study
Condition: Multiple System Atrophy
Interventions: Radiation: PET (Positron Emission Tomography) Study;   Other: Brain MRI  (magnetic resonance imaging);   Drug: Fluoxétine / Placebo
7 Unknown  Fipamezole in Neurogenic Orthostatic Hypotension
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Parkinson's Disease;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Fipamezole
8 Recruiting Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach
Condition: Multiple System Atrophy
Interventions: Drug: EGCG as putative neuroprotective agent;   Drug: Placebo
9 Recruiting Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA
Condition: Multiple System Atrophy
Interventions: Drug: L-Threo DOPS;   Drug: placebo
10 Recruiting AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA Patients
Condition: Multiple System Atrophy (MSA)
Interventions: Drug: AZD3241;   Drug: Placebo
11 Recruiting The Autonomic Nervous System and Obesity
Conditions: OBESITY;   HYPERTENSION;   PURE AUTONOMIC FAILURE;   SHY-DRAGER SYNDROME
Interventions: Drug: Trimethaphan;   Drug: Pseudoephedrine
12 Recruiting Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA
Conditions: Multiple System Atrophy;   Neurodegenerative Diseases
Interventions: Biological: AFFITOPE® PD01A + Adjuvant;   Biological: AFFITOPE® PD03A + Adjuvant;   Biological: Adjuvant without active component
13 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
14 Recruiting Magnetic Resonance Spectroscopy in Autonomic Failure
Conditions: Pure Autonomic Failure;   Multiple System Atrophy
Intervention: Procedure: Magnetic Resonance Spectroscopy Imaging
15 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
16 Recruiting Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy;   Vascular Parkinsonism
Intervention: Other: MRI exam of the brain
17 Recruiting Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Losartan;   Drug: Captopril;   Drug: Placebo
18 Recruiting Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Abdominal compression with inflatable cuff;   Other: Sham abdominal compression with inflatable cuff
19 Recruiting Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Passive heat stress;   Other: Control (non-heating)
20 Recruiting Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
Conditions: Parkinson's Disease (PD);   Parkinsonism;   Progressive Supranuclear Palsy (PSP);   Multiple System Atrophy (MSA)
Intervention:

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