66 studies found for:    Open Studies | "Pigmentation Disorders"
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Rank Status Study
1 Unknown  Use of Epidermal Expansion System for Epidermal Grafting on Hypopigmented Skin and Surgical Wounds
Conditions: Surgical Wound;   Hypo-pigmented Skin
Intervention: Device: Momelan Technologies Epidermal Graft Harvesting System
2 Recruiting Study of Factors Regulating Mast Cell Proliferation
Condition: Mastocytosis
Intervention:
3 Recruiting Patient-Reported Outcome Questionnaire for Systemic Mastocytosis
Conditions: Aggressive Systemic Mastocytosis (ASM);   Systemic Mastocytosis With Associated Clonal Hematological Non-mast Cell Lineage Disease (SM-AHNMD);   Mast Cell Leukemia (MCL);   Smoldering Systemic Mastocytosis (SSM);   Indolent Systemic Mastocytosis (ISM) [ISM Subgroup Fully Recruited]
Intervention: Other: Interview
4 Recruiting In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions
Conditions: Nevus;   Racial Melanosis;   Primary Acquired Melanosis;   Conjunctival Malignant Melanoma
Intervention: Procedure: HRT III with Non-Contact Cornea Rostock Module
5 Recruiting Brentuximab Vedotin in Treating Patients With Advanced Systemic Mastocytosis or Mast Cell Leukemia
Conditions: Aggressive Systemic Mastocytosis;   Mast Cell Leukemia;   Systemic Mastocytosis
Interventions: Drug: brentuximab vedotin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Other: questionnaire administration
6 Unknown  A Phase 3 Study to Compare Efficacy and Safety of Masitinib to Placebo in the Treatment of Patients With Smouldering Systemic, Indolent Systemic or Cutaneous Mastocytosis With Handicap
Conditions: Smouldering Systemic Mastocytosis;   Indolent Systemic Mastocytosis;   Cutaneous Mastocytosis With Handicap;   Mastocytosis
Interventions: Drug: masitinib (AB1010);   Drug: placebo
7 Recruiting Clinical, Cellular, and Molecular Investigation Into Oculocutaneous Albinism
Conditions: Albinism;   Oculocutaneous Albinism;   Foveal Hypoplasia;   Hypopigmentation;   Nystagmus
Intervention:
8 Recruiting A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies
Conditions: Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Nasal Type Extranodal NK/T-cell Lymphoma;   Aplastic Anemia;   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   Chronic Eosinophilic Leukemia;   Chronic Myelomonocytic Leukemia;   Chronic Neutrophilic Leukemia;   Essential Thrombocythemia;   Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue;   Juvenile Myelomonocytic Leukemia;   Mastocytosis;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable;   Nodal Marginal Zone B-cell Lymphoma;   Polycythemia Vera;   Previously Treated Myelodysplastic Syndromes;   Primary Myelofibrosis;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Adult Diffuse Small Cleaved Cell Lymphoma;   Recurrent Adult Grade III Lymphomatoid Granulomatosis;   Recurrent Adult Hodgkin Lymphoma;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma;   Recurrent Grade 1 Follicular Lymphoma;   Recurrent Grade 2 Follicular Lymphoma;   Recurrent Marginal Zone Lymphoma;   Recurrent Mycosis Fungoides/Sezary Syndrome;   Recurrent Small Lymphocytic Lymphoma;   Recurrent/Refractory Childhood Hodgkin Lymphoma;   Refractory Anemia;   Refractory Anemia With Ringed Sideroblasts;   Refractory Hairy Cell Leukemia;   Refractory Multiple Myeloma;   Secondary Myelodysplastic Syndromes;   Splenic Marginal Zone Lymphoma;   T-cell Large Granular Lymphocyte Leukemia;   Waldenström Macroglobulinemia
Interventions: Drug: Fludarabine;   Drug: Thiotepa;   Radiation: Total Body Irradiation (TBI);   Biological: Donor Lymphocyte Infusion (DLI);   Drug: Cyclophosphamide (CY);   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Device: Allogeneic hematopoietic stem cell transplantation;   Procedure: Peripheral blood stem cell transplantation (PBSCT)
9 Recruiting Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Conditions: Cockayne Syndrome;   Skin Cancer;   Xeroderma Pigmentosum;   Trichothiodystrophy;   Genodermatosis
Intervention:
10 Unknown  Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?
Condition: Kidney Failure, Chronic
Intervention: Drug: vitamin C, intravenous injection
11 Recruiting Screening Protocol for Genetic Diseases of Mast Cell Homeostasis and Activation
Conditions: Piebaldism;   Idiopathic Anaphylaxis;   Allergy;   Chronic Urticara;   Angioedema
Intervention:
12 Not yet recruiting Pancreatic Cancer Screening of High-Risk Residents of Arkansas
Conditions: Pancreatic Neoplasms;   Peutz-Jegher's Syndrome;   BRCA1 Gene Mutation;   BRCA2 Gene Mutation;   Ataxia Telangiectasia;   Familial Atypical Mole-Malignant Melanoma Syndrome;   Colorectal Neoplasms, Hereditary Nonpolyposis;   Hereditary Pancreatitis
Intervention: Other: Pancreatic Cancer Screening
13 Not yet recruiting Radiotherapy or Imiquimod in Complex Lentigo Maligna
Condition: Lentigo Maligna
Interventions: Drug: Imiquimod;   Radiation: Radiotherapy
14 Not yet recruiting Mohs and Immunofluorescence for Malignant Melanoma In Situ
Conditions: Lentigo Maligna;   Melanoma In Situ
Interventions: Procedure: H&E;   Procedure: IHC MART-1;   Procedure: IF MART-1;   Procedure: IF cocktail
15 Unknown  Prevalence of Carbohydrate Intolerance in Lean and Obese Children
Conditions: Obesity;   Glucose Intolerance;   Diabetes;   Acanthosis Nigricans
Intervention:
16 Unknown  Evaluate the Lightening Effect of the Whitening Cosmetic Product BEX-2011
Condition: Solar Lentigines
Intervention: Other: skin whitening cosmetic product
17 Not yet recruiting Fractional Laser in Combination With UVB Therapy in Vitiligo Patients
Condition: Vitiligo
Interventions: Device: Fractional CO2 laser;   Other: NB-UVB therapy;   Drug: Fluticasone Propionate Cream 0.05%
18 Recruiting The Cancer of the Pancreas Screening-5 CAPS5)Study
Conditions: Pancreas Cancer;   Peutz-Jeghers Syndrome;   Gene Mutation;   Germline Mutation Carrier;   Lynch Syndrome
Intervention: Drug: Human synthetic secretin
19 Recruiting Cancer Risk in Carriers of the Gene for Xeroderma Pigmentosum
Conditions: Xeroderma Pigmentosum;   Melanoma;   Squamous Cell Carcinoma;   Basal Cell Carcinoma;   Skin Cancer
Intervention:
20 Not yet recruiting Open-label Pilot Study of Abatacept for the Treatment of Vitiligo
Condition: Vitiligo
Intervention: Drug: Abatacept

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