Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
63 studies found for:    Open Studies | "Muscle Spasticity"
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Rank Status Study
1 Recruiting Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients
Conditions: Muscle Spasticity;   Multiple Sclerosis
Interventions: Biological: incabotulinumtoxinA;   Biological: Placebo
2 Recruiting Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity
Conditions: Dystonia;   Focal Dystonia;   Musician's Dystonia;   Muscle Spasticity
Interventions: Procedure: BoNT injection;   Procedure: US guidance;   Procedure: E-stim Guidance
3 Recruiting Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
Conditions: Cerebral Palsy;   Spasticity
Interventions: Drug: IncobotulinumtoxinA (8 Units per kg body weight);   Drug: IncobotulinumtoxinA (6 Units per kg body weight);   Drug: IncobotulinumtoxinA (2 Units per kg body weight)
4 Unknown  Energy Costs of Spasticity in Spinal Cord Injury: A Pilot Investigation
Conditions: Basal Energy Expenditure;   Spasticity
Intervention: Other: Weaning of Antispasticity Medication
5 Recruiting Reliability of an Algorithm to Diagnose Spasticity
Condition: Spasticity
Intervention:
6 Recruiting The Effect of Extracorporeal Shock Wave Therapy on Spasticity
Condition: Spasticity
Intervention: Device: Shock wave
7 Recruiting Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury
Conditions: Spinal Cord Injury;   Spasticity
Intervention: Device: Duolith® SD 1 "T-Top" (Storz Medical AG, Switzerland)
8 Recruiting Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
Condition: Spasticity
Interventions: Device: repetitive Transcranial Magnetic Stimulation (rTMS);   Device: Sham repetitive Transcranial Magnetic Stimulation
9 Recruiting Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia
Conditions: Spasticity;   Focal Dystonia;   Tremor, Limb
Interventions: Device: E-stim;   Device: Ultrasound
10 Recruiting Action of Baclofen Capsules in Spasticity Due to Multiple Sclerosis
Condition: Spasticity
Interventions: Drug: Baclofen dose 1;   Drug: Baclofen dose 2;   Drug: Placebo
11 Recruiting Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis
Condition: Spasticity
Interventions: Drug: Baclofen ER Capsules;   Drug: Placebo GRS
12 Not yet recruiting Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.
Conditions: Spasticity;   Multiple Sclerosis
Interventions: Drug: Sativex;   Drug: Placebo
13 Recruiting A Clinical Evaluation Of The Safety Of Baclofen Er Capsules (Grs) When Administered Once Daily To Subjects With Spasticity Due To Multiple Sclerosis (Ms): An Open Label, Long Term, Safety Trial
Condition: Spasticity
Intervention: Drug: Baclofen
14 Recruiting SISTERS: Spasticity In Stroke Study - Randomized Study
Condition: Severe Spasticity
Intervention: Drug: intrathecal baclofen
15 Not yet recruiting ASIS for Botox in Upper Limb Spasticity
Conditions: Upper Limb Spasticity Unilaterally in Adults With History of Stroke;   Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.
Interventions: Drug: Gadolinium;   Drug: Efficacy of Botox intramuscularly at Week 6;   Drug: Efficacy of Botox intramuscularly at Week 12,;   Drug: Efficacy of Botox intramuscularly at Week 18;   Drug: Efficacy of Botox intramuscularly at Week 24;   Drug: Efficacy of Botox intramuscularly at Week 30;   Drug: Efficacy of Botox subdermally at Week 6;   Drug: Efficacy of Botox subdermally at Week 12;   Drug: Efficacy of Botox subdermally at Week 18;   Drug: Efficacy of Botox subdermally at Week 24;   Drug: Efficacy of Botox subdermally at Week 30;   Drug: Adverse Reactions of Botox intramuscularly;   Drug: Adverse Reactions of Botox subdermally
16 Recruiting An Adult Spasticity Registry of OnabotulinumtoxinA Treatment
Condition: Muscle Spasticity
Intervention: Drug: onabotulinumtoxinA
17 Recruiting BOTOX® Treatment in Pediatric Lower Limb Spasticity
Conditions: Pediatrics;   Muscle Spasticity;   Cerebral Palsy
Interventions: Biological: botulinum toxin Type A;   Drug: Normal Saline (Placebo)
18 Recruiting BOTOX® Treatment in Pediatric Upper Limb Spasticity
Conditions: Pediatrics;   Muscle Spasticity;   Cerebral Palsy;   Stroke
Interventions: Biological: botulinum toxin Type A;   Drug: Normal Saline (Placebo)
19 Recruiting BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity
Conditions: Pediatrics;   Muscle Spasticity;   Cerebral Palsy
Intervention: Biological: botulinum toxin Type A
20 Recruiting BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity
Conditions: Pediatrics;   Muscle Spasticity;   Cerebral Palsy;   Stroke
Intervention: Biological: botulinum toxin Type A

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