| 1 |
NCT03201198 |
Recruiting |
Active for Life: Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Active Life
- Behavioral: Chair exercises
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Other
|
- Time spent in Physical Activity and sedentary behavior (baseline)
- Time spent in Physical Activity and sedentary behavior (end of intervention)
- Time spent in Physical Activity and sedentary behavior (3 month follow-up)
- (and 6 more...)
|
183 |
All |
50 Years and older (Adult, Older Adult) |
NCT03201198 |
HUM00119545 |
ActiveCOPD |
July 27, 2017 |
February 2022 |
February 2022 |
June 28, 2017 |
September 18, 2018 |
|
- University of Michigan School of Nursing
Ann Arbor, Michigan, United States
|
|
| 2 |
NCT02439333 |
Recruiting |
Prospective Randomized Study of Nasal High Flow in Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
- Lung Diseases, Obstructive
|
- Device: Nasal high flow cannula (Fisher & Paykel Healthcare, Auckland, New Zealand)
- Device: nasal catheter or Venturi mask
|
Interventional
|
Not Applicable |
- Li Xuyan
- Beijing Chao Yang Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Treatment failure criteria
- Length of hospital stay
- Costs of hospitalization expenses
|
320 |
All |
40 Years to 90 Years (Adult, Older Adult) |
NCT02439333 |
2015-KE-63 |
|
July 2015 |
June 2019 |
June 2019 |
May 8, 2015 |
November 14, 2018 |
|
- Department of respiratory and critical care medicine,Beijing Chao-yang Hospital
Beijing, Beijing, China
|
|
| 3 |
NCT02978144 |
Recruiting |
Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Radiation: SPECT-CT imaging
- Drug: AxV-128/Tc
|
Interventional
|
Phase 2 |
- Columbia University
- National Heart, Lung, and Blood Institute (NHLBI)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
|
32 |
All |
18 Years and older (Adult, Older Adult) |
NCT02978144 |
AAAR0417
1R01HL131960-01 |
|
June 15, 2017 |
July 2019 |
July 2019 |
November 30, 2016 |
August 14, 2018 |
|
- Columbia University Medical Center
New York, New York, United States
|
|
| 4 |
NCT03882372 |
Not yet recruiting |
Nasal High Flow to Maintain the Benefits of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients |
- Chronic Obstructive Pulmonary Disease
|
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Endurance capacity
- Quality of life: Saint George's Respiratory Questionnaire
- Quality of life: Chronic Obstructive Pulmonary Disease Assessement Test
- (and 15 more...)
|
46 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03882372 |
PPR-NHF |
PPR-NHF |
April 1, 2019 |
November 1, 2021 |
April 1, 2022 |
March 20, 2019 |
March 20, 2019 |
|
- ADIR Association
Bois-Guillaume, France
|
|
| 5 |
NCT03014609 |
Recruiting |
Cardiovascular Risk and Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- University Hospital, Grenoble
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Change of the pulse wave velocity (PWV)
- Monitoring of COPD exacerbations compared to evolution of PWV
- Relationship between the new cardiovascular (CV) events and the evolution of the PWV.
- (and 3 more...)
|
150 |
All |
18 Years to 85 Years (Adult, Older Adult) |
NCT03014609 |
38RC16.245 |
ECO-COPD |
January 2017 |
November 2020 |
December 2025 |
January 9, 2017 |
October 16, 2018 |
|
- University Grenoble Hospital
Grenoble, La Tronche, France
|
|
| 6 |
NCT03280355 |
Recruiting |
The Effects of Singing Training for Patients With Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Singing training
- Behavioral: Physical Training
|
Interventional
|
Not Applicable |
- University of Aarhus
- Region Zealand
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- 6 Minutes Walk Distance (6MWD)
- Pedometer
- St. George's Respiratory Questionnaire (SGRQ)
- (and 5 more...)
|
220 |
All |
18 Years and older (Adult, Older Adult) |
NCT03280355 |
AU_Singing |
|
August 1, 2017 |
November 2018 |
November 2018 |
September 12, 2017 |
May 7, 2018 |
|
- Rudersdal Health Centre
Birkerod, Denmark - Fakse Health Centre
Fakse, Denmark - Vesthimmerland Health Centre
Farso, Denmark - (and 8 more...)
|
|
| 7 |
NCT02468635 |
Recruiting |
Rehabilitation of Patients With Lung Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Other: upper limb exercises
- Other: without training for upper limb
|
Interventional
|
Not Applicable |
- Federal University of Bahia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in distance of the six-minute walk test
- Change in quality of life
- Change in forced expiratory volume in one second
- (and 3 more...)
|
2 |
All |
40 Years to 85 Years (Adult, Older Adult) |
NCT02468635 |
ca141078 |
PR |
June 2015 |
June 2017 |
May 2018 |
June 11, 2015 |
May 30, 2017 |
|
- Federal University of Bahia
Salvador, Bahia, Brazil
|
|
| 8 |
NCT03893409 |
Recruiting
New |
GIRH Chronic Obstructive Pulmonary Disease Observational Study |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- zili zhang
- The First Affiliated Hospital of Guangzhou Medical University
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- difference of FEV1 at 12 months from baseline
|
10000 |
All |
40 Years to 70 Years (Adult, Older Adult) |
NCT03893409 |
Respiratory disease of GIRH |
|
August 10, 2018 |
December 30, 2020 |
December 30, 2022 |
March 28, 2019 |
March 28, 2019 |
|
- The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
|
|
| 9 |
NCT03845257 |
Recruiting |
Correlation of FeNO, Blood Eosinophils, Bronchoalveolar Lavage Findings and Bronchial Epithelium Histopathology in Patients With Chronic Obstructive Pulmonary Disease and Asthma |
- Obstructive Lung Diseases
|
- Diagnostic Test: Blood sampling, FeNO, bronchoalveolar lavage, bronchoscopic tissue sampling
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Assessment of eosinophilic inflammation by correlating tissue eosinophilia with eosinophil count in blood/BAL and FeNO measurement.
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03845257 |
Protocol DG3.0 - 25.06.2018 |
|
February 14, 2019 |
August 31, 2020 |
August 31, 2020 |
February 19, 2019 |
February 19, 2019 |
|
- Macquarie University Sydney
Sydney, New South Wales, Australia - Division of Clinical Infectious Diseases/Research Center Borstel
Borstel, Germany - Thoraxklinik University Heidelberg
Heidelberg, Germany
|
|
| 10 |
NCT03646851 |
Recruiting |
Aspergillus and Chronic Obstructive Pulmonary Disease Evolution |
- Chronic Obstructive Pulmonary Disease
|
- Diagnostic Test: Questionnaries
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire, Amiens
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- presence of aspergillus in sputum or respiratory samples
- Dyspnea with MMRC score
|
100 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03646851 |
PI2017_843_0024 |
AspergBPCO |
March 15, 2018 |
March 15, 2018 |
March 15, 2019 |
August 24, 2018 |
August 24, 2018 |
|
- CH Abbeville
Abbeville, France - CHU Amiens-Picardie
Amiens, France - Clinique de l'Europe
Amiens, France - CHU St Quentin
Saint-Quentin, France
|
|
| 11 |
NCT03900195 |
Recruiting
New |
The Effectiveness of Bottle-PEP in Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Forced expiratory volume in the first minute
- 6 minute walking test
- St. George's Quality of Life Score
|
50 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT03900195 |
09.2019.052 |
|
January 21, 2019 |
January 2020 |
January 2020 |
April 2, 2019 |
April 2, 2019 |
|
- Marmara University School of Medicine Department of Physical Medicine and Rehabilitation
Istanbul, Turkey
|
|
| 12 |
NCT03885128 |
Recruiting |
Intra Versus Extra-thoracic Oscillations in Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Device: High frequency extra thoracic oscillations vest
- Device: Intrathoracic oscillatory quake
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Pulmonary function test (spirometry)
- impulse oscillometry
|
60 |
Male |
45 Years to 72 Years (Adult, Older Adult) |
NCT03885128 |
P.T.REC/012/001741 |
|
November 1, 2017 |
May 1, 2019 |
May 30, 2019 |
March 21, 2019 |
March 21, 2019 |
|
- Faculty of physical therapy
Dokki, Giza, Egypt
|
|
| 13 |
NCT03566667 |
Recruiting |
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Metoprolol
- Drug: Standard care
|
Interventional
|
Phase 4 |
- Ole Frobert, MD, PhD
- Region Örebro County
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Mortality, exacerbations and cardiovascular events
- Mortality
- Exacerbations
- Cardiovascular events
|
1700 |
All |
40 Years and older (Adult, Older Adult) |
NCT03566667 |
BRONCHIOLE-2017 |
|
June 12, 2018 |
December 31, 2020 |
December 31, 2020 |
June 25, 2018 |
June 25, 2018 |
|
- University Hospital of Örebro
Örebro, Sweden
|
|
| 14 |
NCT03050424 |
Recruiting |
Iron and Chronic Obstructive Pulmonary Disease (COPD) Exercise Trial |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Ferric Carboxymaltose
- Drug: Sodium Chloride 0.9%
|
Interventional
|
Phase 2 |
- Royal Brompton & Harefield NHS Foundation Trust
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Constant Rate Cycle Ergometry (75% Max Load)
- Quality of Life
- Muscle Oxygen Delivery
- (and 2 more...)
|
40 |
All |
18 Years to 100 Years (Adult, Older Adult) |
NCT03050424 |
2016LF003B
2016-000829-39
16/EE/0355 |
ICE-T |
April 1, 2017 |
October 1, 2018 |
January 1, 2019 |
February 10, 2017 |
May 12, 2017 |
|
- Royal Brompton & Harefield NHS Foundation Trust
London, United Kingdom
|
|
| 15 |
NCT03853642 |
Not yet recruiting |
Blood Eosinophil Measurements in Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- Universitair Ziekenhuis Brussel
- Vrije Universiteit Brussel
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Within-day within-subject level changes of blood eosinophils
|
50 |
All |
18 Years and older (Adult, Older Adult) |
NCT03853642 |
UniversitairZB 18-409 |
|
February 2019 |
December 2019 |
December 2019 |
February 25, 2019 |
February 25, 2019 |
|
|
|
| 16 |
NCT03819517 |
Not yet recruiting |
Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Dietary Supplement: Resveratrol
- Other: Placebo
|
Interventional
|
Not Applicable |
- Virginia Commonwealth University
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in Sirt1 concentrations
- Change in vascular health
- Change in Systemic Inflammation
- (and 2 more...)
|
24 |
All |
21 Years and older (Adult, Older Adult) |
NCT03819517 |
HM20014536 |
|
April 2019 |
September 2021 |
September 2021 |
January 28, 2019 |
April 16, 2019 |
|
- Virginia Commonwealth University
Richmond, Virginia, United States
|
|
| 17 |
NCT03797768 |
Not yet recruiting |
Community-based Management of Chronic Obstructive Pulmonary Disease in Nepal |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Behavioural-FCHV Visit
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Forced Expiratory Volume in 1 second
- Proportion of risk factors of COPD between intervention and control arm
|
924 |
All |
30 Years to 80 Years (Adult, Older Adult) |
NCT03797768 |
AUTBA18 |
COBIN-P |
March 1, 2019 |
August 30, 2020 |
November 30, 2020 |
January 9, 2019 |
January 9, 2019 |
|
|
|
| 18 |
NCT03704545 |
Recruiting |
Clinical Impact of Pharmaceutical Consultations in Patients Treated for Chronic Obstructive Pulmonary Disease at Home |
- Chronic Obstructive Pulmonary Disease
|
- Other: Pharmaceutical consultation at the hospital
- Other: Pharmaceutical consultation at the pharmacy
- Other: Follow-up pharmaceutical consultation at the pharmacy
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Nīmes
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Number of exacerbation events
- Number of visits to the attending physician
- Number of visits to the pulmonologist
- (and 7 more...)
|
226 |
All |
18 Years and older (Adult, Older Adult) |
NCT03704545 |
NIMAO/2017-03/JMK-01 |
BPCObs |
January 18, 2019 |
June 2020 |
June 2020 |
October 12, 2018 |
February 1, 2019 |
|
- Nimes University Hospital
Nîmes, France
|
|
| 19 |
NCT03453606 |
Recruiting |
Respiratory Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Other: Home respiratory rehabilitation
- Other: Center respiratory rehabilitation
|
Interventional
|
Not Applicable |
- University Hospital, Lille
- Ministry of Health, France
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Change from baseline the 6 minutes Stepper test at 2 months
- Change from baseline the 6 minutes Stepper test at 6 and 12 months
- Percentage of patients expressing a preference marked for home-based respiratory rehabilitation or respiratory rehabilitation in center
- (and 5 more...)
|
670 |
All |
18 Years and older (Adult, Older Adult) |
NCT03453606 |
2017_08
2017-A02393-50
PREPS-16-249 |
REHABDO |
October 24, 2018 |
January 2022 |
January 2022 |
March 5, 2018 |
February 18, 2019 |
|
- Centre hospitalier de béthune
Béthune, France - Hôpital Calmette, CHU
Lille, France
|
|
| 20 |
NCT02050022 |
Recruiting |
Chronic Obstructive Pulmonary Disease Biomarker Study |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- University of British Columbia
- Genome British Columbia
- Centres of Excellence for Commercialization and Research
- (and 4 more...)
|
Other / Industry |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
|
500 |
All |
19 Years to 95 Years (Adult, Older Adult) |
NCT02050022 |
H11-00786 |
|
April 2013 |
December 2017 |
December 2018 |
January 30, 2014 |
May 31, 2017 |
|
- St. Paul's Hospital
Vancouver, British Columbia, Canada
|
|
| 21 |
NCT01177618 |
Recruiting |
Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- Brigham and Women's Hospital
- National Heart, Lung, and Blood Institute (NHLBI)
|
Other / NIH |
- Observational Model: Family-Based
- Time Perspective: Cross-Sectional
|
|
2000 |
All |
Child, Adult, Older Adult |
NCT01177618 |
1437
R01HL113264
U01HL089856 |
|
July 1994 |
July 2022 |
July 2022 |
August 9, 2010 |
January 23, 2019 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
|
| 22 |
NCT03492359 |
Recruiting |
Thora-3DI™ for Evaluation of Severity of Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
- Device: Thora-3Di
- Device: Body Plethysmography
- Device: Spirometry
|
Interventional
|
Not Applicable |
- Landon Pediatric Foundation
- Pneumacare Ltd
|
Other / Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Screening
|
- Difference in SLP Breath Timing indices measured in seconds and between Patients and Healthy Subjects
- Difference in SLP derived Relative Contribution (measured in %) between Patients and Healthy Subjects
- Difference in SLP derived Phase (measured in degrees) between Patients and Healthy Subjects
- (and 4 more...)
|
105 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03492359 |
SLP CL1 |
SLPCOPD |
May 1, 2017 |
October 1, 2018 |
January 1, 2019 |
April 10, 2018 |
April 10, 2018 |
|
- Ventura County Medical Center
Ventura, California, United States
|
|
| 23 |
NCT03660501 |
Recruiting |
Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - an Observational Study |
- Chronic Obstructive Pulmonary Disease
|
- Device: Continuous monitoring system
|
Observational
|
|
- University Hospital Bispebjerg and Frederiksberg
- Technical University of Denmark
- Herlev and Gentofte Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Any serious adverse events
- Mortality
- Readmission
|
200 |
All |
18 Years to 100 Years (Adult, Older Adult) |
NCT03660501 |
WARD-COPD_v1.1 |
WARD-COPD |
September 12, 2018 |
December 2019 |
June 2020 |
September 6, 2018 |
April 11, 2019 |
|
- Bispebjerg Hospital
Copenhagen, Denmark - Gentofte Hospital
Hellerup, Denmark
|
|
| 24 |
NCT03450603 |
Recruiting |
Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Number of participants with acute exacerbations of chronic obstructive pulmonary disease
|
200 |
All |
40 Years and older (Adult, Older Adult) |
NCT03450603 |
XH-17-019 |
|
December 10, 2017 |
December 30, 2019 |
December 30, 2019 |
March 1, 2018 |
February 1, 2019 |
|
- Department of Respiratory Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
|
|
| 25 |
NCT03627858 |
Recruiting |
Fixed Dose Triple Therapy in Severe Chronic Obstructive Pulmonary Disease in a Real World Setting |
- Chronic Obstructive Pulmonary Disease
|
- Drug: beclomethasone / formoterol / glycopyrronium
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Inhalation technique score
- Treatment adherence score
- Number of inhaled doses recorded by dose counter since previous visit
- (and 4 more...)
|
250 |
All |
40 Years and older (Adult, Older Adult) |
NCT03627858 |
CHIESI_NIS_0001 |
TRIVOLVE |
August 1, 2018 |
March 2020 |
June 2020 |
August 14, 2018 |
December 11, 2018 |
|
- ZNA Middelheim
Antwerp, Belgium - Universitair Ziekenhuis Antwerpen
Antwerp, Belgium - GZA Campus Sint-Vincentius
Antwerp, Belgium - (and 12 more...)
|
|
| 26 |
NCT03282526 |
Not yet recruiting |
Volume Parameters vs Flow Parameters in Assessment of Reversibility in Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Diagnostic Test: Whole body plethysmography
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Diagnostic
|
- Assess the response pattern to inhaled short acting B2 agonist
|
100 |
All |
40 Years to 60 Years (Adult) |
NCT03282526 |
PFTs in COPD |
|
September 30, 2017 |
September 2018 |
December 2018 |
September 14, 2017 |
September 14, 2017 |
|
|
|
| 27 |
NCT03910985 |
Not yet recruiting
New |
Assessment of Reactance Parameters Measured by the Forced Oscillation Technique for the Bronchodilator Response in Subjects With Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
|
Interventional
|
Phase 4 |
- Centre Hospitalier Universitaire Dinant Godinne - UCL Namur
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Acute inspiratory capacity increase
|
80 |
All |
40 Years and older (Adult, Older Adult) |
NCT03910985 |
B039201938727 |
|
April 23, 2019 |
December 31, 2021 |
December 31, 2021 |
April 10, 2019 |
April 17, 2019 |
|
|
|
| 28 |
NCT03646864 |
Recruiting |
A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Drug: ACT-541468
- Other: Placebo
|
Interventional
|
Phase 1 |
- Idorsia Pharmaceuticals Ltd.
|
Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Mean SaO2 during total sleep time (TST) after multiple-dose administration (i.e., at Night 5) as measured by finger pulse oximetry and PSG
|
28 |
All |
18 Years and older (Adult, Older Adult) |
NCT03646864 |
ID-078-109
2018-001828-19 |
|
November 15, 2018 |
May 31, 2019 |
May 31, 2019 |
August 24, 2018 |
March 21, 2019 |
|
- Advanced Sleep Research
Berlin, Germany - Klinische Forschungsgruppe Nord
Dresden, Germany - Klinische Forschungsgruppe Nord
Hannover, Germany - (and 2 more...)
|
|
| 29 |
NCT03414541 |
Recruiting |
Safety And Efficacy Study Of Orally Administered DS102 In Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Drug: DS102
- Other: Placebo
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in induced sputum differential neutrophil count from baseline to Week 12
- Number of Treatment Emergent Adverse Events (TEAEs) in each treatment group leading to treatment discontinuation.
- Change in induced sputum neutrophil differential count from baseline
- Change in St Georges Respiratory Questionnaire (SGRQ) from baseline
|
45 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03414541 |
DS102A-03 |
|
September 24, 2017 |
August 2018 |
November 2018 |
January 30, 2018 |
February 2, 2018 |
|
- Manchester Evaluations Unit (MEU)
Manchester, Wythenshawe, United Kingdom - Celerion
Belfast, United Kingdom
|
|
| 30 |
NCT03071731 |
Recruiting |
Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Bronchodilators
- Drug: Placebos
|
Interventional
|
Not Applicable |
- Laval University
- Institut Universitaire de Cardiologie et Pneumologie de Québec
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Other
|
- Glittre ADL-test time completion
- Perceptual variables
- Breathing discomfort
- (and 10 more...)
|
34 |
All |
40 Years and older (Adult, Older Adult) |
NCT03071731 |
2017-2739 |
Glittre |
April 13, 2017 |
June 15, 2019 |
June 15, 2019 |
March 7, 2017 |
July 6, 2018 |
|
- Centre de recherche-Institut Universitaire de Cardiologie et Pneumologie de Québec
Quebec City, Quebec, Canada
|
|
| 31 |
NCT02860728 |
Recruiting |
Resistance Training to Prehabilitate Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Individualized Resistance Training
|
Interventional
|
Not Applicable |
- University of British Columbia
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Dyspnea
- Exercise Tolerance
- Secondary Dyspnea Outcomes
- (and 2 more...)
|
20 |
All |
40 Years and older (Adult, Older Adult) |
NCT02860728 |
H16-01019 |
|
August 2016 |
August 2018 |
August 2018 |
August 9, 2016 |
November 9, 2017 |
|
- University of British Columbia
Kelowna, British Columbia, Canada
|
|
| 32 |
NCT03244137 |
Recruiting |
Effects of Pulmonary Rehabilitation on Cognitive Function in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Other: Pulmonary rehabilitation
|
Observational
|
|
- ADIR Association
- CHU de Rouen - Accueil
- Groupe Hospitalier du Havre
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Baseline cognitive function
- Cognitive function after pulmonary rehabilitation
- Cognitive function : follow up
- (and 13 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT03244137 |
PR-COPD |
|
September 4, 2017 |
November 1, 2019 |
September 1, 2020 |
August 9, 2017 |
January 9, 2019 |
|
- Bonnevie
Bois-Guillaume, France - Médrinal
Le Havre, France
|
|
| 33 |
NCT02884830 |
Not yet recruiting |
Nocturnal Continuous Positive Airway Pressure in Chronic Obstructive Pulmonary Disease Patients |
- Chronic Obstructive Pulmonary Disease
|
- Device: continuous positive airway pressure
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire Saint Pierre
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- sleep quality
- static hyperinflation
|
20 |
All |
18 Years to 100 Years (Adult, Older Adult) |
NCT02884830 |
AK/16-05-73/4668AD |
|
January 2019 |
December 2021 |
December 2021 |
August 31, 2016 |
August 3, 2018 |
|
|
|
| 34 |
NCT03157986 |
Recruiting |
Effects of Whole-Body Vibration Training Versus Balance Training in Patients With Severe Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Other: Balance Training on a vibration platform
- Other: Conventional Balance training
|
Interventional
|
Not Applicable |
- Klinikum Berchtesgadener Land der Schön-Kliniken
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Balance Performance during semi Tandem stance
- Change in muscle power during counter movement jump
- Change in performance of the 5-Repetition-Raise-Test
- (and 9 more...)
|
48 |
All |
50 Years to 80 Years (Adult, Older Adult) |
NCT03157986 |
WBVT Balance Study |
|
May 15, 2017 |
August 1, 2019 |
October 1, 2019 |
May 17, 2017 |
February 27, 2019 |
|
- Schön Klinik Berchtesgadener Land
Schoenau Am Koenigssee, Bavaria, Germany
|
|
| 35 |
NCT03546907 |
Recruiting |
Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Any Inhaled Corticosteroids as prescribed by treating physician as standard of care
- Drug: Any Long Acting Beta Agonist as prescribed by treating physician as standard of care
- Drug: Any Long Acting Muscarinic Agonist as prescribed by treating physician as standard of care
- Drug: Any short-acting β agonist as prescribed by treating physician as standard of care
|
Interventional
|
Phase 2 |
- Sanofi
- Regeneron Pharmaceuticals
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Rate of moderate-to-severe acute Exacerbations in chronic obstructive pulmonary disease (AECOPD) patients
- Change in pre-bronchodilator forced expiratory volume in 1 second (FEV1)
- Time to first COPD Exacerbation
- (and 2 more...)
|
340 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03546907 |
ACT15104
2017-003290-34
U1111-1194-2134 |
|
July 16, 2018 |
December 2019 |
April 2020 |
June 5, 2018 |
April 19, 2019 |
|
- Investigational Site Number 8400002
Los Angeles, California, United States - Investigational Site Number 8400003
Riverside, California, United States - Investigational Site Number 8400006
Rolling Hills Estates, California, United States - (and 83 more...)
|
|
| 36 |
NCT03159091 |
Recruiting |
Clinical Trial of Efficacy and Safety of Rengalin in the Treatment of Cough in Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Rengalin
- Drug: Placebo
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Percentage of patients with a positive treatment response
- Severity of cough compared to baseline
- Percentage of patients with ≥50% lesser cough severity
- (and 2 more...)
|
238 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03159091 |
MMH-RN-005 |
|
June 16, 2017 |
June 2019 |
June 2019 |
May 18, 2017 |
January 10, 2019 |
|
- Regional state budgetary health care institution "Regional Clinical Hospital"
Barnaul, Russian Federation - Regional state budget health care institution "City Hospital No. 5, Barnaul"
Barnaul, Russian Federation - NUZ "Road Clinical Hospital at the station Chelyabinsk JSC" RZhD "
Chelyabinsk, Russian Federation - (and 19 more...)
|
|
| 37 |
NCT02348060 |
Recruiting |
Outcomes Data of Adipose Stem Cells to Treat Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Change from Baseline in Overall Quality of Life Over the Course of a 12 Month Period as Measured by the Chronic Respiratory Disease Questionnaire - Self-Administered Individualized (CRQ-SAI)
- Change from Baseline in Overall Breathing Comfort at Month 12 as Measured by Participants' Responses to the Chronic Respiratory Disease Questionnaire - Self-Administered Individualized (CRQ-SAI) Dyspnea Subscale
- Change from Baseline in Overall Fatigue at Month 12 as Measured by Participants' Responses to the Chronic Respiratory Disease Questionnaire - Self-Administered Individualized (CRQ-SAI) Fatigue Subscale
- (and 2 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT02348060 |
SVF01COPD
ASCCOPD-01 |
|
November 2015 |
May 2019 |
May 2019 |
January 28, 2015 |
August 31, 2018 |
|
- StemGenex
San Diego, California, United States
|
|
| 38 |
NCT03216603 |
Recruiting |
Health Literacy in People With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Health literacy intervention group
|
Interventional
|
Not Applicable |
- Lovisenberg Diakonale Hospital
- University of Oslo
- Norwegian Extra Foundation for Health and Rehabilitation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Change of admissions
- Change of health literacy
- Change of disease specific quality of life
- (and 5 more...)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03216603 |
298 |
|
November 1, 2017 |
August 31, 2020 |
August 31, 2020 |
July 13, 2017 |
February 26, 2019 |
|
- Lovisenberg Diakonale Hospital
Oslo, Norway
|
|
| 39 |
NCT03398772 |
Recruiting |
Effects of a Comprehensive Health Coaching Program in Advanced Chronic Obstructive Pulmonary Disease. |
- Chronic Obstructive Pulmonary Disease Severe
- Chronic Obstructive Pulmonary Disease End Stage
|
- Behavioral: Comprehensive Health Coaching Program
|
Interventional
|
Not Applicable |
- Taipei Medical University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Supportive Care
|
- Change from Baseline Lung function at 3 months, 6months
- Change from Baseline Exercise Tolerance at 3 months, 6months
- Change from Baseline Health-related quality of life at 3 months, 6months
- (and 5 more...)
|
50 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03398772 |
N201704032 |
|
March 1, 2018 |
July 31, 2020 |
July 31, 2020 |
January 12, 2018 |
April 26, 2018 |
|
- Taipei Medical Hospital-Shuang Ho Hospital,Ministry of Health and Welfare
Taipei, Taiwan
|
|
| 40 |
NCT02272634 |
Recruiting |
A Phase 2a Study to Assess Safety, Daily Symptoms, Pharmacokinetics (PK), and Biomarkers of YPL-001 in Chronic Obstructive Pulmonary Disease (COPD) Patients |
- Chronic Obstructive Pulmonary Disease
|
- Drug: YPL-001 low dose
- Drug: YPL-001 high dose
- Drug: placebo
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Safety and tolerability of multiple doses of YPL-001 as assessed by number of adverse events (AEs)
- Safety and tolerability of multiple doses of YPL-001 as assessed by clinical laboratory tests
- Safety and tolerability of multiple doses of YPL-001 as assessed by vital signs
- (and 7 more...)
|
61 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT02272634 |
YPL-001_YJP-130403 |
|
June 4, 2015 |
October 31, 2017 |
October 31, 2017 |
October 23, 2014 |
August 22, 2017 |
|
- UAB Lung Health Center
Birmingham, Alabama, United States - Florida Pulmonary Research Institute, LLC
Winter Park, Florida, United States - Aventiv Research Inc.
Columbus, Ohio, United States - Temple Lung Center, Temple University Hospital
Philadelphia, Pennsylvania, United States
|
|
| 41 |
NCT03923803 |
Not yet recruiting
New |
Diagnostic Values of C-reactive Protein and Procalcitonin in Predicting Bacterial Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Diagnostic Test: C- reactive protein
- Diagnostic Test: Pro calcitonin
|
Observational
|
|
|
Other |
- Observational Model: Other
- Time Perspective: Cross-Sectional
|
- The level of C-reactive protein between Infection and Non-infectious inflammatory response in acute exacerbations of Chronic obstructive pulmonary disease patients
|
90 |
All |
18 Years and older (Adult, Older Adult) |
NCT03923803 |
CRPPC |
|
July 2019 |
June 2020 |
October 2020 |
April 23, 2019 |
April 23, 2019 |
|
|
|
| 42 |
NCT03197818 |
Recruiting |
Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) |
- COPD (Chronic Obstructive Pulmonary Disease)
|
- Drug: CHF 5993 100/6/12.5 µg
- Drug: 160 µg budesonide + 4.5 µg formoterol fumarate
|
Interventional
|
Phase 3 |
- Chiesi Farmaceutici S.p.A.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from Baseline in pre-dose FEV1(Forced Expiratory Volume within the first second) at week 24
- Change from Baseline in 2-hour post-dose FEV1 at week 24
- Change from Baseline in pre-dose morning FEV1 and 2-hour post-dose morning FEV1 at week 24
- (and 3 more...)
|
990 |
All |
40 Years and older (Adult, Older Adult) |
NCT03197818 |
CCD-5993AA1-14
China
Taiwan
South Korea |
TRIVERSYTI |
December 13, 2016 |
September 30, 2019 |
September 30, 2019 |
June 23, 2017 |
July 6, 2018 |
|
- Chiesi clinical Trial Site 156031
Beijing, Beijing, China - Chiesi Clinical Trial Site 156026
Beijing, Beijing, China - Chiesi clinical Trial Site 156017
Beijing, Beijing, China - (and 52 more...)
|
|
| 43 |
NCT02563314 |
Recruiting |
Comparison of Two Oxygen Setting During Non-invasive Mechanical Ventilation of Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified
|
- Device: Non-invasive mechanical ventilation - Normoxia
- Device: Non-invasive mechanical ventilation - Controlled hypoxemia
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Saint Etienne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Other
|
- urinary output (ml)
- Changes in CO2 levels
- respiratory workload during non-invasive mechanical ventilation (occlusion pressure (cm H2O) to 100 ms after the onset of inspiration)
- (and 10 more...)
|
88 |
All |
18 Years and older (Adult, Older Adult) |
NCT02563314 |
1408025
ANSM |
OXYSET |
March 22, 2017 |
September 2019 |
September 2019 |
September 30, 2015 |
December 28, 2017 |
|
- CHU de CLERMONT-FERRAND
Clermont-ferrand, France - CHu de GRENOBLE
Grenoble, France - CHU de la Pitié-Salpêtrière
Paris, France - CHU de SAINT-ETIENNE
Saint-etienne, France
|
|
| 44 |
NCT02985918 |
Recruiting |
High-intensity Versus Conventional-intensity Noninvasive Positive Pressure Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: the HAPPEN Study (HAPPEN) |
- Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
- Device: High-intensity NPPV
- Device: Conventional-intensity NPPV
|
Interventional
|
Not Applicable |
- Beijing Chao Yang Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Intubation rate
- The decrements of PaCO2 measured at 2 hours after enrollment.
- The decrements of PaCO2 measured at 6 hours after enrollment.
- (and 9 more...)
|
600 |
All |
18 Years and older (Adult, Older Adult) |
NCT02985918 |
BeijingCYH-ICU-004 |
|
December 31, 2017 |
December 31, 2018 |
March 31, 2019 |
December 7, 2016 |
April 6, 2018 |
|
- The Second Hospital of Baoji
Baoji, China - The Third Hospital of Baoji
Baoji, China - Beijing Chao-Yang Hospital
Beijing, China - (and 24 more...)
|
|
| 45 |
NCT03890224 |
Not yet recruiting
New |
Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients |
- Chronic Obstructive Pulmonary Disease
- COPD Exacerbation
|
|
Interventional
|
Not Applicable |
- Clinact
- Fondation du Souffle
- Assistance Publique - Hôpitaux de Paris
|
Other |
- Allocation: Randomized
- Intervention Model: Sequential Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- admission-free survival
- Overall survival
- Frequency of exacerbations requiring hospitalization
- (and 13 more...)
|
400 |
All |
18 Years and older (Adult, Older Adult) |
NCT03890224 |
R2M
2018-A01872-53 |
|
March 15, 2019 |
March 15, 2022 |
December 31, 2024 |
March 26, 2019 |
March 26, 2019 |
|
|
|
| 46 |
NCT03531489 |
Recruiting |
Study of Ambulatory Respiratory Assist Device in Chronic Obstructive Pulmonary Disease Patients |
- COPD
- Chronic Obstructive Pulmonary Disease
|
|
Interventional
|
Not Applicable |
- Right-Air
- University of Pennsylvania
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Assess distance travelled during 6-minute walk tests performed with and without device.
- Assess for patient improvement in shortness of breath scores
|
30 |
All |
18 Years and older (Adult, Older Adult) |
NCT03531489 |
Penn 826372 |
|
April 26, 2018 |
December 30, 2018 |
December 30, 2018 |
May 21, 2018 |
May 21, 2018 |
|
- John Hansen-Flaschen
Philadelphia, Pennsylvania, United States
|
|
| 47 |
NCT03449056 |
Recruiting |
High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
- High-flow Nasal Cannula
|
|
Interventional
|
Phase 3 |
- Poitiers University Hospital
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
25 |
All |
18 Years to 100 Years (Adult, Older Adult) |
NCT03449056 |
OPTINEB |
OPTINEB |
January 11, 2019 |
January 2020 |
April 2020 |
February 28, 2018 |
February 12, 2019 |
|
- C.H.U. de Poitiers
Poitiers, France
|
|
| 48 |
NCT02065921 |
Recruiting |
Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort |
- Chronic Obstructive Pulmonary Disease
- COPD Exacerbation
|
|
Observational
|
|
- Prof. Dr. Jörg Leuppi
- Cantonal Hosptal, Baselland
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Number of exacerbation
- Disease progression
|
265 |
All |
40 Years and older (Adult, Older Adult) |
NCT02065921 |
EKBB170/06 |
|
September 2006 |
September 2018 |
September 2019 |
February 19, 2014 |
August 7, 2017 |
|
- Cantonal Hospital Baselland, Internal medicine University clinic
Liestal, Baselland, Switzerland
|
|
| 49 |
NCT02870998 |
Recruiting |
Impacts of a Continuing Education Activity Targeted at COPD Case Managers |
- Lung Diseases, Obstructive
|
- Other: Active learning
- Other: Passive learning
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Performance
- Satisfaction
- Learning
- (and 2 more...)
|
300 |
All |
Child, Adult, Older Adult |
NCT02870998 |
MP-10-2016-2591 |
|
June 2016 |
November 2019 |
November 2019 |
August 18, 2016 |
February 27, 2019 |
|
- Institut universitaire de cardiologie et de pneumologie de Québec
Quebec, Canada
|
|
| 50 |
NCT03848819 |
Not yet recruiting |
Effect of Portable NIV on Operational Chest Wall Volumes in COPD |
- Chronic Obstructive Pulmonary Disease
|
- Device: VitaBreath device
|
Interventional
|
Not Applicable |
- Northumbria University
- North Tyneside General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- The magnitude of change in thoracoabdominal wall dynamic hyperinflation.
- Compartmental thoracoabdominal wall volumes (rib cage and abdominal volumes) assessed by OEP.
- Electromyographic activation (expressed as fractions of peak activation and in absolute terms in mV) assessed by surface electromyography
- (and 2 more...)
|
12 |
All |
40 Years and older (Adult, Older Adult) |
NCT03848819 |
259201 |
|
May 1, 2019 |
December 20, 2019 |
December 20, 2019 |
February 21, 2019 |
February 21, 2019 |
|
- Northumbria University
Newcastle upon Tyne, United Kingdom
|
|
| 51 |
NCT03011853 |
Recruiting |
Survival After Failed First-line Non-invasive Ventilation in Acute on Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Airways Disease Exacerbated
- Critical Care
|
|
Observational
|
|
- Swedish Intensive Care Registry
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Six month survival
- One year survival
- ICU length of stay
|
3500 |
All |
16 Years and older (Child, Adult, Older Adult) |
NCT03011853 |
NIV4COPD |
|
January 2008 |
July 2018 |
December 2018 |
January 5, 2017 |
March 21, 2018 |
|
- Västerviks sjukhus
Vastervik, Sweden
|
|
| 52 |
NCT01180803 |
Recruiting |
Efficacy of Oxygen Therapy Delivered by Systems Using Oxygen-Saving Valves in COPD Patients |
- LUNG DISEASES, OBSTRUCTIVE
|
- Device: pulse oxygen supplementation devices
- Device: continuous oxygen
|
Interventional
|
Not Applicable |
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- oxygen saturation during 6 minutes walking test
- Walking distance during the 6 minutes walking test
|
200 |
All |
45 Years to 80 Years (Adult, Older Adult) |
NCT01180803 |
EVAL- CLIN A00690-39 |
|
July 2010 |
September 2018 |
December 2018 |
August 12, 2010 |
November 22, 2017 |
|
- Fédération ANTADIR
Paris, France
|
|
| 53 |
NCT03741855 |
Recruiting |
Evaluating the Cloud DX Platform as a Tool for Self-management and Asynchronous Remote-monitoring of COPD |
- Chronic Obstructive Pulmonary Disease
|
- Device: Cloud Dx Kit with self-monitoring
- Device: Cloud Dx Kit with remote-monitoring
|
Interventional
|
Not Applicable |
- Women's College Hospital
- Markham Stouffville Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- Self-management and Activation
- Quality of Life and Respiratory symptoms
- Patient Knowledge of COPD
- (and 5 more...)
|
123 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03741855 |
WCHCDX-001 |
|
January 1, 2018 |
January 2019 |
January 2019 |
November 15, 2018 |
November 15, 2018 |
|
- Markham-Stouffville Hospital
Markham, Ontario, Canada
|
|
| 54 |
NCT03844711 |
Recruiting |
Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated |
- Chronic Obstructive Pulmonary Disease
|
- Other: Electrical diaphragmatic stimulation
- Other: Inspiratory muscle training
- Other: Conventional physiotherapy
|
Interventional
|
Not Applicable |
- Hospital de Clinicas de Porto Alegre
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Respiratory muscle strength - maximum expiratory pressure (MEP)
- Respiratory muscle strength - maximum inspiratory pressure (MIP)
- Pulmonary function - forced expiratory volume in the first second
- (and 13 more...)
|
60 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03844711 |
2018-0078 |
|
February 16, 2019 |
August 1, 2020 |
December 1, 2020 |
February 18, 2019 |
March 29, 2019 |
|
- Federal University of Rio Grande do Sul
Porto Alegre, Rio Grande Do Sul, Brazil
|
|
| 55 |
NCT03152994 |
Recruiting |
The Early Predictors for Developing Type 2 Diabetes Mellitus in Patients With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
- Type 2 Diabetes Mellitus
|
- Other: Checking fasting blood glucose(FBG)
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- fasting blood glucose(FBG)
- routine blood parameters（composite outcome measure）
- inspiratory muscle function（composite outcome measure）
- (and 2 more...)
|
500 |
All |
Child, Adult, Older Adult |
NCT03152994 |
CX0422 |
|
April 1, 2017 |
April 1, 2020 |
May 1, 2020 |
May 15, 2017 |
May 15, 2017 |
|
- Zhujiang Hospital,Southern Medical Universicity
Guangzhou, Guangdong, China
|
|
| 56 |
NCT03555097 |
Recruiting |
Effects of Non-invasive Ventilation on Respiratory Mechanics and NRD in Patients With Stable COPD |
- Chronic Obstructive Pulmonary Disease
|
- Procedure: incremental pressure support
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Diaphragmatic function
- Respiratory pressure
- Respiratory volume
- Degree of dyspnea
|
20 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03555097 |
2018-HXNK-010 |
|
July 10, 2018 |
January 1, 2019 |
March 1, 2019 |
June 13, 2018 |
October 9, 2018 |
|
- Zhujiang Hospital,Southern Medical Universicity
Guangzhou, Guangdong, China
|
|
| 57 |
NCT03653611 |
Recruiting |
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2) |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Other: On-site Practice Assessment
- Other: Clinical Staff Questionnaires
- Other: Patient Opinion Surveys
- (and 2 more...)
|
Observational
|
|
- Weill Medical College of Cornell University
- National Heart, Lung, and Blood Institute (NHLBI)
- University of Michigan
- (and 9 more...)
|
Other / NIH |
- Observational Model: Other
- Time Perspective: Prospective
|
- Primary care clinician perspective on implementing CAPTURE into primary care practice.
- Primary care clinician knowledge about respiratory care at the provider level.
- Primary care clinician attitudes and beliefs regarding respiratory care and communication within their current practice.
- (and 6 more...)
|
350 |
All |
Child, Adult, Older Adult |
NCT03653611 |
1803019032-2
R01HL136682-01 |
CAPTURE |
August 30, 2018 |
May 1, 2019 |
July 1, 2019 |
August 31, 2018 |
January 4, 2019 |
|
- LANet
Los Angeles, California, United States - High Plains Research Network
Aurora, Colorado, United States - COPD Foundation
Miami, Florida, United States - (and 3 more...)
|
|
| 58 |
NCT02237820 |
Recruiting |
Dexamethasone Versus Prednisone in Heart Failure Patients, Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease. |
- Heart Failure
- Chronic Obstructive Pulmonary Disease
|
- Drug: Dexamethasone
- Drug: Prednisone
|
Interventional
|
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Length of hospital stay
- Change from Baseline in body weight at 14 days
- Rate of re-admission
|
80 |
All |
40 Years and older (Adult, Older Adult) |
NCT02237820 |
no specific protocol ID |
|
November 2014 |
January 2020 |
April 2020 |
September 11, 2014 |
January 11, 2019 |
|
- Beilinson Hospital, Rabin Medical Center
Petah Tikva, Israel
|
|
| 59 |
NCT00858520 |
Recruiting |
Serum, Plasma, DNA and Tissue Bank in Chronic Obstructive Pulmonary Disease and Lung Cancer |
- Chronic Obstructive Pulmonary Disease
- Lung Cancer
|
|
Observational
|
|
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Serological, cytological, histological and genetic analysis of biomarkers or genes which are involved in the pathogenesis of COPD/Emphysema/Lungcancer.
|
2000 |
All |
25 Years and older (Adult, Older Adult) |
NCT00858520 |
B32220072389
S50623 |
|
October 2007 |
December 2018 |
December 2019 |
March 10, 2009 |
September 4, 2013 |
|
- Katholieke Universiteit Leuven
Leuven, Flanders, Belgium
|
|
| 60 |
NCT03227523 |
Recruiting |
Nonspecific Low Back Pain in Association With Chronic Obstructive Pulmonary Disease |
- Low Back Pain
- Chronic Obstructive Pulmonary Disease
|
|
Observational
|
|
- University of Alcala
- Comité de Ética para la Investigación del Hospital Universitario Ramón y Cajal
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- Respiratory muscle strength (MIP = maximum inspiratory pressure).
- Respiratory muscle strength (MEP = maximum expitaroy pressure).
- Postural control (Motor control test: KLAT = knee lift abdominal test).
- (and 6 more...)
|
134 |
All |
40 Years and older (Adult, Older Adult) |
NCT03227523 |
010-17 |
|
June 1, 2017 |
March 31, 2018 |
May 31, 2018 |
July 24, 2017 |
July 24, 2017 |
|
- University of Alcalá
Alcalá de Henares, Madrid, Spain
|
|
| 61 |
NCT03532243 |
Recruiting |
Acute Effects of Incremental Inspiratory Loads on Respiratory Mechanics and NRD in Patient With Stable COPD. |
- Chronic Obstructive Pulmonary Disease
|
- Procedure: incremental inspiratory load
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Diaphragmatic function
- Respiratory pressure
- Respiratory volume
- Degree of dyspnea
|
20 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03532243 |
2018-HXNK-007 |
|
April 1, 2018 |
October 1, 2018 |
February 1, 2019 |
May 22, 2018 |
May 22, 2018 |
|
- Zhujiang Hospital,Southern Medical Universtiy
Guangzhou, Guangdong, China
|
|
| 62 |
NCT03751670 |
Recruiting |
Pulmonary Rehabilitation During Acute Exacerbations of Chronic Obstructive Pulmonary Disease: a Mixed-methods Approach |
- Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
- Other: Pulmonary Rehabilitation
- Drug: Daily medical treatment
|
Interventional
|
Not Applicable |
- Aveiro University
- Fundação para a Ciência e a Tecnologia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- COPD Assessment test
- Symptoms of dyspnea and fatigue
- Lung function measurement
- (and 4 more...)
|
50 |
All |
18 Years and older (Adult, Older Adult) |
NCT03751670 |
POCI-01-0145-FEDER-028806PhDAM |
|
September 1, 2018 |
December 31, 2021 |
December 31, 2022 |
November 22, 2018 |
November 27, 2018 |
|
- University of Aveiro
Aveiro, Portugal
|
|
| 63 |
NCT02614105 |
Recruiting |
Urinary Incontinence Amongst Women With Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
- Urinary Incontinence
|
- Procedure: Pelvic floor muscle training
- Procedure: Cough-suppression therapy
- Other: Control
|
Interventional
|
Not Applicable |
- Ostfold Hospital Trust
- St. Olavs Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- International Consultation on Incontinence Questionnaire Short form (ICIQ_SF)
- Cough symptoms
- Chronic Obstructive Pulmonary Disease symptoms
- (and 5 more...)
|
96 |
Female |
18 Years and older (Adult, Older Adult) |
NCT02614105 |
3342 |
UriCO |
November 2015 |
December 2018 |
December 2019 |
November 25, 2015 |
December 14, 2017 |
|
- St Olavs Hospital
Trondheim, Norway - Østfold Hospital Trust
Moss, Østfold, Norway
|
|
| 64 |
NCT03500042 |
Recruiting |
Effects of Different Modes of Respiratory MuscleTraining on Respiratory Mechanics and NRD in Patient With Stable COPD. |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Device: inspiratory pressure threshold device
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Diaphragmatic function
- Respiratory pressure
- Respiratory volume
- respiratory work
|
20 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03500042 |
2018-HXNK-008 |
|
March 1, 2018 |
December 1, 2018 |
March 1, 2019 |
April 17, 2018 |
April 17, 2018 |
|
- Zhujiang Hospital,Southern Medical Universtiy
Guangzhou, Guangdong, China
|
|
| 65 |
NCT03008746 |
Recruiting |
Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem |
- Chronic Obstructive Pulmonary Disease
|
- Other: water used for oral wash
- Other: sputum
- Other: oral wash
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Presence of P. aeruginosa resistance to imipenem (OprD mutation)
- Pulmonary microbiota
- questionnaire: the modified Respiratory Medical Council (MMRC)
- St George's respiratory questionnaire
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT03008746 |
PA16090 |
MiPAD |
January 12, 2017 |
January 2021 |
January 2022 |
January 2, 2017 |
February 25, 2019 |
|
|
|
| 66 |
NCT02872090 |
Recruiting |
Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD) |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Indacaterol
- Drug: Glycopyrronium
- Drug: Tiotropium
- (and 2 more...)
|
Interventional
|
Phase 4 |
- Centre Hospitalier Universitaire de Besancon
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Low-frequency (LF)/High-frequency (HF) ratio in supine position during a tilt table test after bronchodilators inhalation
- Slope of baroreflex in supine position
- LF / HF ratio derived from the spectral analysis of R-R intervals measured after verticalisation during a tilt table test
- (and 4 more...)
|
48 |
All |
50 Years to 75 Years (Adult, Older Adult) |
NCT02872090 |
P/2015/255 |
LAB-Card |
March 2016 |
March 2019 |
December 2019 |
August 18, 2016 |
May 30, 2018 |
|
- Centre Hospitalier Régional Universitaire
Besançon, France
|
|
| 67 |
NCT03173508 |
Recruiting |
Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude |
- Chronic Obstructive Pulmonary Disease
|
- Drug: ACETAZOLAMIDE oral capsule
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Zurich
- National Center of Cardiology and Internal Medicine, Kyrgyzstan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- pulmonary artery pressure
- cardiac output
- right heart dimensions
- (and 3 more...)
|
100 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03173508 |
2017-00137E |
|
May 24, 2017 |
December 2018 |
December 2019 |
June 1, 2017 |
June 7, 2017 |
|
- National Center for Cardiology and Internal Medicine
Bishkek, Kyrgyzstan
|
|
| 68 |
NCT03432026 |
Not yet recruiting |
Phenotypes of COPD |
- Chronic Obstructive Pulmonary Disease
|
- Device: High resolution computed tomography scan of the chest.
|
Observational
|
|
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Rate of risk factors of COPD in non smokers.
|
50 |
All |
Child, Adult, Older Adult |
NCT03432026 |
COPD |
|
April 1, 2019 |
April 1, 2020 |
April 1, 2021 |
February 13, 2018 |
June 27, 2018 |
|
|
|
| 69 |
NCT02924870 |
Recruiting |
Long-term Effect of an Health Education Program on Daily Physical Activity in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Other: Health education program
- Other: Conventional management
|
Interventional
|
Phase 4 |
- Hospital Universitario La Paz
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Physical activity level
- Steps per day
- Daily minutes of moderate-high intensity activity
- (and 7 more...)
|
128 |
All |
35 Years and older (Adult, Older Adult) |
NCT02924870 |
HULP PI-4447 |
EA-EPOC |
October 2016 |
March 2020 |
March 2020 |
October 5, 2016 |
September 11, 2018 |
|
- Hospital Universitario La Paz-IdiPAZ
Madrid, Spain
|
|
| 70 |
NCT02978703 |
Recruiting |
EvAluation of Clinical Effectiveness Of RoLenium Administered With Elpenhaler in Chronic Obstructive Pulmonary Disease (COPD) patientS in Daily Clinical Practice, in Greece |
- Chronic Obstructive Pulmonary Disease
|
- Drug: COPD Pharmacologic Substance
|
Observational
|
|
- Elpen Pharmaceutical Co. Inc.
|
Industry |
- Observational Model: Other
- Time Perspective: Prospective
|
- Efficacy assessed by Spirometry
- Efficacy assessed by MRC dyspnea questionnaire
- Safety assessed by number of exacerbations
- Patient Satisfaction assessed by FSI-10 questionnaire
|
2000 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02978703 |
2016-HAL-EL-67 |
AEOLOS |
January 2017 |
December 2018 |
December 2018 |
December 1, 2016 |
August 21, 2018 |
|
- University Hospital of Crete
Iraklion, Crete, Greece - University Hospital of Herakleion
Irákleion, Greece
|
|
| 71 |
NCT02842463 |
Recruiting |
6-minute Stepper Test and Pulmonary Rehabilitation in Patients With Chronicle Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
- Pulmonary Rehabilitation
- 6-minute Stepper Test
|
- Other: 2 times : 6-minute stepper test with a rest of 20min between each test.
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Relation between plateau heart rate (bpm) from the first and last 3 minutes of the 6-minute stepper test and heart rate (bpm) from first ventilatory threshold from cardiopulmonary exercise testing.
- Relation between minimal SpO2 (%)from the 6-minute stepper test and SpO2 (%) from first ventilatory threshold from cardiopulmonary exercise testing.
- Blood pressure (mmHg) before and after every 6-minute stepper test using electrical blood pressure device.
- Steps during 6-minute stepper test using stepper device.
|
80 |
All |
18 Years and older (Adult, Older Adult) |
NCT02842463 |
6STaR |
6STaR |
July 2016 |
December 2019 |
June 2020 |
July 25, 2016 |
January 10, 2019 |
|
- ADIR Association
Bois-Guillaume, France - Centre Hostalier Intercommunal Elbeuf-Louviers-Val de Reuil
Elbeuf, France - Groupe Hospitalier du Havre
Le Havre, France
|
|
| 72 |
NCT02252588 |
Recruiting |
The Effect of Chlorhexidine on the Oral and Lung Microbiota in Chronic Obstructive Pulmonary Disease |
- Chronic Obstructive Pulmonary Disease
|
- Drug: Chlorhexidine
- Other: Placebo
|
Interventional
|
Phase 2 |
- University of Minnesota - Clinical and Translational Science Institute
- Veterans Medical Research Foundation
- Flight Attendant Medical Research Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in sputum bacteria
- Symptoms of COPD
|
40 |
All |
40 Years to 85 Years (Adult, Older Adult) |
NCT02252588 |
4526 |
CLIMB |
September 2014 |
July 2019 |
September 2019 |
September 30, 2014 |
May 2, 2018 |
|
- VA Medical Center
Minneapolis, Minnesota, United States
|
|
| 73 |
NCT03167034 |
Recruiting |
Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude |
- Chronic Obstructive Pulmonary Disease
|
- Drug: ACETAZOLAMIDE oral capsule
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Zurich
- National Center of Cardiology and Internal Medicine, Kyrgyzstan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- pulmonary artery pressure during exercise
- cardiac output during exercise
- PAP/CO slope during exercise
- Oxygen saturation
|
100 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03167034 |
2017-00137F |
|
May 24, 2017 |
December 2018 |
December 2019 |
May 25, 2017 |
June 7, 2017 |
|
- National Center for Cardiology and Internal Medicine
Bishkek, Kyrgyzstan
|
|
| 74 |
NCT03889964 |
Recruiting
New |
Exercise Capacity in COPD |
- Chronic Obstructive Pulmonary Disease
|
- Other: Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing
|
Observational
|
|
- Klinik für Kardiologie, Pneumologie und Angiologie
- Heinrich-Heine University, Duesseldorf
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Measurement of oxygen uptake during cardiopulmonary exercise testing (% predicted)
- measurement of dyspnoea quantified by the COPD assessment test as well as the modified Medical Research Council Scale
- Measurement of FEV1
- (and 6 more...)
|
100 |
All |
40 Years to 40 Years (Adult) |
NCT03889964 |
17-033 |
|
March 1, 2019 |
January 2020 |
January 2020 |
March 26, 2019 |
March 26, 2019 |
|
- University Hospital Düsseldorf, Division of Cardiology, Pulmonary Disease and Vascular Medicine
Düsseldorf, Germany
|
|
| 75 |
NCT03327181 |
Recruiting |
Short Chain Fatty Acid Metabolism in COPD |
- Chronic Obstructive Pulmonary Disease
|
- Dietary Supplement: short chain fatty acid tracers
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- whole body short-chain fatty acid metabolism
- Fat free mass measured using dual-energy x-ray absorptiometry
- Fat mass measured using dual-energy x-ray absorptiometry
- (and 10 more...)
|
60 |
All |
45 Years to 100 Years (Adult, Older Adult) |
NCT03327181 |
2017-0112 |
SCFA |
April 19, 2017 |
April 2019 |
April 2020 |
October 31, 2017 |
September 26, 2018 |
|
- Texas A&M University
College Station, Texas, United States
|
|
| 76 |
NCT03892629 |
Not yet recruiting
New |
Baduanjin Exercise for Patients With GOLD 2-3 Stable COPD on Pulmonary Rehabilitation |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: Baduanjin exercise
- Device: Instrument rehabilitation
|
Interventional
|
Not Applicable |
- ShuGuang Hospital
- Shanghai Zhongshan Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- St. George's respiratory questionnaire (SGRQ)
- Six-minute walk test (6MWT)
- Pulmanory function indicators (FEV1/FVC, FEV1pred%)
- (and 5 more...)
|
240 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03892629 |
2018YFC1313601003 |
|
April 2019 |
October 2019 |
December 2019 |
March 27, 2019 |
April 1, 2019 |
|
- Shanghai Shuguang Hospital
Shanghai, China
|
|
| 77 |
NCT03899558 |
Not yet recruiting
New |
The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD |
- Chronic Obstructive Pulmonary Disease
|
- Device: Humidified nasal high-flow device
|
Interventional
|
Not Applicable |
- Guy's and St Thomas' NHS Foundation Trust
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Time to 30-day hospital readmission following index hospitalisation with AECOPD
- Recruitment rate of eligible patients
- Adherence with completion of clinical outcome measures (symptom diary)
- (and 13 more...)
|
80 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03899558 |
242147 |
|
April 1, 2019 |
August 31, 2021 |
August 31, 2021 |
April 2, 2019 |
April 2, 2019 |
|
|
|
| 78 |
NCT03489746 |
Recruiting |
Steroid Withdrawal Intervention in Fife and Tayside |
- Chronic Obstructive Pulmonary Disease
|
- Other: ICS withdrawal protocol
- Other: Standard care
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Frequency of moderate and severe exacerbations of COPD
- Respiratory Hospitalizations
- Success of ICS withdrawal
- (and 3 more...)
|
2000 |
All |
40 Years and older (Adult, Older Adult) |
NCT03489746 |
2016RC23 |
SWIFT |
May 1, 2018 |
September 2019 |
September 2020 |
April 5, 2018 |
September 11, 2018 |
|
- NHS Tayside
Dundee, Perthshire, United Kingdom - NHS FIfe
Kirkcaldy, United Kingdom
|
|
| 79 |
NCT03698682 |
Recruiting |
Short Compared With Standard Duration of Antibiotic Treatment for AECOPD |
- Chronic Obstructive Pulmonary Disease
|
|
Interventional
|
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Mortality
- Rate of additional antibiotherapy course
|
520 |
All |
18 Years and older (Adult, Older Adult) |
NCT03698682 |
AECOPD levofloxacine Study |
AECOPD |
September 2013 |
December 31, 2018 |
December 31, 2018 |
October 8, 2018 |
October 23, 2018 |
|
- Emergency department of university hospital Fattouma Bourguiba of Monastir
Monastir, Tunisia
|
|
| 80 |
NCT03156673 |
Recruiting |
Treatment of COPD by Autologous Transplantation of Bronchial Basal Cells |
- Chronic Obstructive Pulmonary Disease
|
- Biological: bronchial basal cells
|
Interventional
|
Early Phase 1 |
- First Affiliated Hospital of Shantou University Medical College
- Regend Therapeutics
- Tongji University
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Forced expiratory volume in one second (FEV1)
- Forced vital capacity (FVC)
- Diffusion capacity of CO (DLCO)
- (and 6 more...)
|
20 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03156673 |
2017112 |
|
April 1, 2017 |
December 31, 2021 |
June 30, 2022 |
May 17, 2017 |
May 17, 2017 |
|
- the First Affiliated Hospital of Shantou University Medical College
Shantou, Guang Dong, China
|
|
| 81 |
NCT03196089 |
Recruiting |
Effect of Short-term Oxygen During CPET in COPD |
- Chronic Obstructive Pulmonary Disease
|
- Procedure: Oxygen application
|
Interventional
|
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Watt
- Exercise time
- Peak Oxygen uptake
- (and 4 more...)
|
20 |
All |
20 Years to 80 Years (Adult, Older Adult) |
NCT03196089 |
KEK-ZH-NR. 2012-0251_2 |
|
June 2, 2017 |
December 2018 |
December 2018 |
June 22, 2017 |
June 22, 2017 |
|
- University Hospital Zurich, Division of Pneumology
Zürich, Switzerland
|
|
| 82 |
NCT03188627 |
Recruiting |
Autologous Bronchial Basal Cell Transplantation for Treatment of COPD |
- Chronic Obstructive Pulmonary Disease
|
- Biological: Bronchial basal cells
|
Interventional
|
Phase 1
Phase 2 |
- Regend Therapeutics
- Southwest Hospital, China
- Tongji University
|
Industry / Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Forced expiratory volume in one second (FEV1)
- Forced vital capacity (FVC)
- The ratio of forced expiratory volume in the first one second to the forced vital capacity (FEV1/FVC)
- (and 7 more...)
|
20 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03188627 |
20170206 |
|
May 19, 2017 |
August 18, 2019 |
December 2019 |
June 15, 2017 |
August 31, 2018 |
|
- First Affiliated Hospital of the Third Military University, PLA (Southwest Hospital)
Chongqing, Chongqing, China
|
|
| 83 |
NCT03177811 |
Recruiting |
Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude |
- Chronic Obstructive Pulmonary Disease
|
- Drug: ACETAZOLAMIDE oral capsule
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Zurich
- National Center of Cardiology and Internal Medicine, Kyrgyzstan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change in postural control
- Change in arterial oxygen saturation
- acute mountain sickness
|
100 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03177811 |
2017-00137B |
|
May 24, 2017 |
December 2017 |
December 2019 |
June 6, 2017 |
October 27, 2017 |
|
- National Center of Cardiology and Internal Medicine
Bishkek, Kyrgyzstan
|
|
| 84 |
NCT03888131 |
Recruiting
New |
Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient |
- Chronic Obstructive Pulmonary Disease
|
- Drug: CHF 1535 100/6 µg pMDI plus Symbicort® Turbohaler® Placebo
- Drug: Symbicort® Turbohaler® plus CHF 1535 pMDI Placebo
|
Interventional
|
Phase 3 |
- Chiesi Farmaceutici S.p.A.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Demonstration of the non-inferiority of CHF 1535 pMDI versus Symbicort® Turbohaler® in terms of pulmonary function
- Effect of CHF 1535 on change from baseline pre-dose morning FEV1
- Effect of CHF 1535 on chnage from Baseline in pre-dose morning Force Vital Capacity (FVC)
- (and 8 more...)
|
750 |
All |
40 Years and older (Adult, Older Adult) |
NCT03888131 |
CCD-01535AC1-02 |
FORSYYN |
July 30, 2018 |
April 2021 |
April 2021 |
March 25, 2019 |
March 25, 2019 |
|
- Site 15604 - Anhui Provincial Hospital
Hefei, Anhui, China - Site 15635 - The Second Hospital of Anhui Medical Hospital
Hefei, Anhui, China - Site 15613 - Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing, China - (and 45 more...)
|
|
| 85 |
NCT03177837 |
Recruiting |
Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude |
- Chronic Obstructive Pulmonary Disease
|
- Drug: ACETAZOLAMIDE oral capsule
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Zurich
- National Center of Cardiology and Internal Medicine, Kyrgyzstan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change in maximal power output during exercise
- Change in peak oxygen uptake during exercise
- Change in cerebral tissue oxygenation during exercise
- (and 2 more...)
|
100 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03177837 |
2017-00137C |
|
May 24, 2017 |
December 2018 |
December 2019 |
June 6, 2017 |
October 27, 2017 |
|
- National Center of Cardiology and Internal Medicine
Bishkek, Kyrgyzstan
|
|
| 86 |
NCT02825043 |
Recruiting |
HFNC Effect on BCSS in Patients With COPD |
- Chronic Obstructive Pulmonary Disease
|
- Device: High-Flow Nasal Cannula
|
Interventional
|
Not Applicable |
- University of Oklahoma
- Fisher and Paykel Healthcare
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Decreased breathlessness, cough and sputum score.
- Decrease COPD exacerbations.
|
30 |
All |
35 Years to 80 Years (Adult, Older Adult) |
NCT02825043 |
6410 |
COPD |
February 2016 |
December 2019 |
December 2019 |
July 7, 2016 |
May 4, 2018 |
|
- University of Oklahoma
Oklahoma City, Oklahoma, United States
|
|
| 87 |
NCT03762330 |
Not yet recruiting |
Structured Comprehensive Intervention to Stimulate Self- Management and Improve Quality of Life in COPD Patients |
- Chronic Obstructive Pulmonary Disease
|
- Behavioral: COPD structured self-management plan.
|
Interventional
|
Not Applicable |
- Jordi Gol i Gurina Foundation
- Institut Catala de Salut
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Quality of life St. George´s Respiratory Questionnaire (SGRQ)
- Intensity of symptoms related to COPD
- Dyspnea score severity
- (and 14 more...)
|
300 |
All |
18 Years and older (Adult, Older Adult) |
NCT03762330 |
P17/055 |
|
February 2019 |
January 2021 |
January 2021 |
December 3, 2018 |
December 4, 2018 |
|
|
|
| 88 |
NCT02674880 |
Not yet recruiting |
Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive Assistance |
- Chronic Obstructive Pulmonary Disease
|
- Drug: HMW-HA
- Other: Placebo
|
Interventional
|
Phase 2 |
- Campus Bio-Medico University
- National Institute of Environmental Health Sciences (NIEHS)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Cumulative time on NIV
- Rate of decline of time on NIV
|
80 |
All |
18 Years and older (Adult, Older Adult) |
NCT02674880 |
15.1(15PT).15 ComEt-CBM |
HAEC-DONA |
March 2016 |
January 2019 |
May 2019 |
February 5, 2016 |
February 5, 2016 |
|
- Università Campus Biomedico di Roma
Roma, RM, Italy
|
|
| 89 |
NCT02980575 |
Recruiting |
Music During Pulmonary Rehabilitation for Patients With COPD |
- Chronic Obstructive Pulmonary Disease
|
- Other: Music
- Other: Exercise
|
Interventional
|
Not Applicable |
- West Park Healthcare Centre
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in end 6-minute walk test dyspnea and fatigue levels
- Multidimensional dyspnea profile
- Change in chronic respiratory disease questionnaire scores
- (and 4 more...)
|
70 |
All |
40 Years and older (Adult, Older Adult) |
NCT02980575 |
16-016-WP |
|
November 2016 |
December 2019 |
June 2020 |
December 2, 2016 |
July 26, 2018 |
|
- West Park Healthcare Centre
Toronto, Ontario, Canada
|
|
| 90 |
NCT03583099 |
Recruiting |
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3) |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Other: COPD plus CAPTURE education and patient-level information
- Other: COPD Education Only
|
Interventional
|
Not Applicable |
- Weill Medical College of Cornell University
- National Heart, Lung, and Blood Institute (NHLBI)
- University of Michigan
- (and 9 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Other
|
- Proportion of CAPTURE+ participants who meet a composite endpoint for diagnosis and management of COPD
- Proportion of CAPTURE+ participants who are referred for or completion of clinical spirometry testing
- Proportion of CAPTURE+ participants who are newly diagnosed with COPD
- (and 13 more...)
|
5000 |
All |
45 Years to 80 Years (Adult, Older Adult) |
NCT03583099 |
1803019032-3
R01HL136682-01 |
CAPTURE |
September 17, 2018 |
July 1, 2021 |
July 1, 2021 |
July 11, 2018 |
January 4, 2019 |
|
- LANet
Los Angeles, California, United States - High Plains Research Network
Aurora, Colorado, United States - COPD Foundation
Miami, Florida, United States - (and 3 more...)
|
|
| 91 |
NCT03581227 |
Recruiting |
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1) |
- Chronic Obstructive Pulmonary Disease (COPD)
|
|
Observational
|
|
- Weill Medical College of Cornell University
- National Heart, Lung, and Blood Institute (NHLBI)
- University of Michigan
- (and 9 more...)
|
Other / NIH |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Sensitivity and specificity of CAPTURE to identify previously undiagnosed patients with clinically significant COPD at baseline
- Sensitivity and specificity of CAPTURE to identify previously undiagnosed patients with clinically significant COPD across sex, ethnic groups, urban vs rural location, and educational status.
- Positive and negative predictive values (PPV and NPV) in different practice settings
- (and 10 more...)
|
5000 |
All |
45 Years to 80 Years (Adult, Older Adult) |
NCT03581227 |
1803019032-1
R01HL136682-01 |
CAPTURE |
September 17, 2018 |
March 1, 2020 |
March 1, 2020 |
July 10, 2018 |
January 4, 2019 |
|
- LANet
Los Angeles, California, United States - High Plains Research Network
Aurora, Colorado, United States - COPD Foundation
Miami, Florida, United States - (and 3 more...)
|
|
| 92 |
NCT03165890 |
Recruiting |
Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Drug: ACETAZOLAMIDE oral capsule
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Zurich
- National Center of Cardiology and Internal Medicine, Kyrgyzstan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- visuomotor learning performance, drug effect
- visuomotor learning performance, altitude effect
- arterial oxygen saturation
|
70 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03165890 |
2017-00137A |
|
May 24, 2017 |
December 2017 |
December 2019 |
May 24, 2017 |
June 7, 2017 |
|
- National Center of Cardiology and Internal Medicine
Bishkek, Kyrgyzstan
|
|
| 93 |
NCT03842904 |
Recruiting |
A Study Comparing the Effects of Trimbow to Fostair in COPD |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Drug: Trimbow pMDI
- Drug: Fostair pMDI
|
Interventional
|
Phase 4 |
- Medicines Evaluation Unit Ltd
- Chiesi UK
|
Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Forced Expired Volume in 1 second (FEV1), L.
- Residual Volume (RV), L.
- Peripheral Respiratory Resistance (R5-R20), kPa/L/s.
- (and 12 more...)
|
24 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03842904 |
MEU 17/361
2018-003113-17 |
TRIFLOW |
December 13, 2018 |
April 2, 2019 |
April 2, 2019 |
February 15, 2019 |
February 15, 2019 |
|
- The Medicines Evaluation Unit (MEU)
Manchester, United Kingdom
|
|
| 94 |
NCT03082924 |
Recruiting |
Surface EMGdi Evaluate the Efficacy of Pulmonary Rehabilitation in Patients With COPD: a Multi Center Prospective Study |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Device: Control group
- Device: Calibrated cycle ergometer
- Device: Threshold loading device
- Device: Calibrated cycle ergometer and threshold loading device
|
Interventional
|
Not Applicable |
- Zhujiang Hospital
- Guangzhou Institute of Respiratory Disease
- The First Affiliated Hospital of Guangdong Pharmaceutical University
- (and 2 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Diaphragmatic function(composite outcome measure)
- Inspiratory muscle function(composite outcome measure)
- Pulmonary Function(composite outcome measure)
- (and 3 more...)
|
500 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03082924 |
CX20160902 |
|
July 2016 |
December 2020 |
June 2021 |
March 17, 2017 |
March 17, 2017 |
|
- Zhujiang Hospital,Southern Medical Universtiy
Guangzhou, Guangdong, China
|
|
| 95 |
NCT03904875 |
Not yet recruiting
New |
Air Pollution and COPD Exacerbation |
- Pollution; Exposure
- Chronic Obstructive Pulmonary Disease
|
- Other: collection of data about each acute exacerbation of COPD
|
Observational
|
|
- Centre Hospitalier Universitaire, Amiens
- Clinique de l'Europe, Amiens
- University Hospital, Lille
|
Other |
- Observational Model: Ecologic or Community
- Time Perspective: Prospective
|
- daily rate of COPD exacerbation consultation in the emergency room of the 3 centers
- ultrathin particles quantity in the air
- chemical composition ultrathin particles
|
480 |
All |
18 Years and older (Adult, Older Adult) |
NCT03904875 |
PI2019_843_0008 |
BePoPi |
January 1, 2020 |
December 31, 2020 |
December 31, 2020 |
April 5, 2019 |
April 5, 2019 |
|
|
|
| 96 |
NCT01905982 |
Recruiting |
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV; part2 |
- Chronic Obstructive Pulmonary Disease
|
- Procedure: reflectory breathing therapy
- Procedure: conventional breathing therapy
|
Interventional
|
Not Applicable |
- Klinikum Berchtesgadener Land der Schön-Kliniken
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in BORG-Scale
- Change in lung volume
- physical activity
- (and 3 more...)
|
44 |
All |
50 Years to 75 Years (Adult, Older Adult) |
NCT01905982 |
RAT 2013
KBerchtesgadener |
|
January 2016 |
May 2019 |
July 2019 |
July 23, 2013 |
February 27, 2019 |
|
- Schön Klinik Berchtesgadener Land
Schönau, Bayern, Germany
|
|
| 97 |
NCT03871933 |
Recruiting |
Autonomic Function in COPD and Risk for Atrial Fibrillation |
- Chronic Obstructive Pulmonary Disease
|
- Other: Measurement of lung function, electrocardiography, echocardiography and autonomic function
|
Observational
|
|
- Heinrich-Heine University, Duesseldorf
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- total atrial conduction time
- Heart rate variability
- Baroreflex sensitivity
- (and 5 more...)
|
50 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03871933 |
16-029 |
|
March 1, 2019 |
June 2019 |
June 2019 |
March 12, 2019 |
March 13, 2019 |
|
- University Hospital Düsseldorf, Division of Cardiology, Pulmonary Disease and Vascular Medicine
Düsseldorf, Germany
|
|
| 98 |
NCT03584269 |
Recruiting |
Innovation in NOn Invasive Ventilation in COPD Patients Treated by Long Term Oxygen Therapy |
- Chronic Obstructive Pulmonary Disease
|
- Device: NIV Device + LTOT
- Device: LTOT
|
Interventional
|
Not Applicable |
- University Hospital, Grenoble
- AGIR à Dom
- ResMed
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Nocturnal transcutaneous pressure CO2 (PtCO2)
- Saint George's Respiratory Questionnaire
- FEV1
- (and 15 more...)
|
38 |
All |
18 Years to 85 Years (Adult, Older Adult) |
NCT03584269 |
38RC17.117 |
INOV-LTOT |
June 28, 2018 |
October 10, 2019 |
April 10, 2020 |
July 12, 2018 |
July 12, 2018 |
|
- University Hospital Grenoble
La Tronche, France
|
|
| 99 |
NCT03083418 |
Recruiting |
The Effect of EDP on Diaphragmatic Function and Neural Respiratory Drive in Patient With AECOPD |
- Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
- Device: control group
- Device: EDP
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Diaphragmatic function(composite outcome measure)
- Degree of dyspnea(composite outcome measure)
- Pulmonary Function(composite outcome measure)
- (and 4 more...)
|
40 |
All |
40 Years to 80 Years (Adult, Older Adult) |
NCT03083418 |
CX20161020 |
|
October 2016 |
August 2018 |
December 2018 |
March 20, 2017 |
January 25, 2018 |
|
- Zhujiang Hospital,Southern Medical Universtiy
Guangzhou, Guangdong, China
|
|
| 100 |
NCT01949727 |
Recruiting |
Examining Vascular Outcomes in COPD Inpatients (AIM 1) Examining Early Rehabilitation on Discharged COPD Patients (AIM 2) |
- Chronic Obstructive Pulmonary Disease (COPD)
|
- Other: AIM 2: Pulmonary Rehabilitation
|
Observational
|
|
- University of Alberta
- University of Calgary
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Inflammatory markers
- Length of Stay (LOS)
- Inflammatory marker (IL-6)
- (and 3 more...)
|
100 |
All |
50 Years and older (Adult, Older Adult) |
NCT01949727 |
Pro00038838
AIHS-CRIO Project Grant |
|
October 2013 |
August 2019 |
August 2019 |
September 24, 2013 |
April 19, 2019 |
|
- University of Alberta Hospital
Edmonton, Alberta, Canada
|
|
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