Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
87 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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Rank Status Study
1 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
2 Recruiting Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Disease
Interventions: Drug: OTX-101 0.05%;   Drug: OTX-101 0.09%;   Drug: Vehicle
3 Recruiting Efficacy of Tocilizumab in Primary Sjögren's Syndrome.
Condition: Primary Sjögren's Syndrome (pSS)
Interventions: Drug: Tocilizumab;   Drug: Placebo
4 Recruiting The Research Registry for Neonatal Lupus
Conditions: Neonatal Lupus;   Systemic Lupus Erythematosus;   Sjogren's Syndrome;   Congenital Heart Block
Intervention: Other: No intervention; observational
5 Unknown  Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
Condition: Dry Eye
Interventions: Drug: FreshKote;   Drug: Systane
6 Recruiting A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: Carboxymethylcellulose Sodium Based Eye Drop;   Drug: Carboxymethylcellulose Sodium 1.0%
7 Recruiting Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome
Conditions: Meibomian Gland Dysfunction;   Dry Eye Syndrome
Interventions: Device: Cutera Xeo Platform-Limelight;   Device: Sciton BroadBand Light
8 Recruiting The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy
Conditions: Thyroid-associated Ophthalmopathy;   Dry Eye Syndrome
Interventions: Drug: Methylprednisolone;   Drug: Esomeprazole
9 Unknown  Oral Nutrition Impact on Tear Film
Condition: Dry Eye Syndrome
Intervention: Dietary Supplement: Omega 3, Vitamins A, D3 and E
10 Unknown  Altaire Gel Forming Solution Versus Refresh Tears for the Treatment of Dry Eye Signs and Symptoms
Condition: Dry Eye Syndromes
Interventions: Drug: Altaire Gel forming solution;   Drug: Refresh Tears
11 Recruiting Effect of Contact Lens With Alginic Acid in Dry Eye Patients
Condition: Dry Eyes
Interventions: Device: Contact Lens with alginic acid;   Device: Contact Lens without alginic acid
12 Recruiting Efficacy and Safety of Abatacept in Patients With Primary Sjögren's Syndrome
Condition: Sjögren's Syndrome
Intervention: Drug: Abatacept SC
13 Not yet recruiting Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome
Condition: Sjogren's Syndrome
Interventions: Drug: Cyclosporin A;   Drug: Prednisone;   Drug: Placebo;   Drug: Calcium carbonate D
14 Not yet recruiting Evaluation of the Reproducibility Inter-observer of the Ultrasound Anomalies of the Salivary Glands in Sjogren's Disease
Condition: Sjogren's Disease
Intervention: Procedure: Ultrasound
15 Recruiting Salivary Biomarkers for Sjögren's Syndrome Detection
Condition: Sjögren's Syndrome
Intervention:
16 Recruiting Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry Eye
Condition: Dry Eye Syndromes
Intervention: Device: Oculeve Intranasal Lacrimal Neurostimulator
17 Recruiting Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease
Conditions: Primary Sjogren Syndrome;   Secondary Sjogren Syndrome;   Aqueous Deficient Dry Eye Disease;   Evaporative Dry Eye Disease
Interventions: Drug: Restasis;   Drug: Refresh Endura
18 Unknown  Green Tea Lozenges for the Management of Dry Mouth
Conditions: Xerostomia;   Sjogren Syndrome;   Dry Mouth
Intervention: Dietary Supplement: Green tea lozenge
19 Unknown  Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS)
Conditions: Sjogren's Syndrome;   Mesenchymal Stem Cells
Intervention: Biological: Allogeneic Mesenchymal Stem Cells (AlloMSC)
20 Recruiting PD of VAY736 in Patients With Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: VAY736;   Drug: Placebo

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Indicates status has not been verified in more than two years