Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
4113 studies found for:    Open Studies | "Immune System Diseases"
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Rank Status Study
1 Recruiting Antibody Production in Immune Disorders
Condition: Immunologic Disease
Intervention:
2 Recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
3 Unknown  Immune Function in Patients With Obstructive Jaundice
Conditions: Obstructive Jaundice;   Disease as Reason for ERCP;   Immune Dysfunction;   Immune Tolerance
Intervention:
4 Recruiting Doxycycline Treatment in Mild Graves' Orbitopathy
Conditions: Graves Ophthalmopathy;   Graves Disease;   Eye Diseases;   Thyroid Diseases;   Endocrine System Diseases;   Eye Diseases, Hereditary;   Hyperthyroidism;   Autoimmune Diseases;   Immune System Diseases
Interventions: Drug: Doxycycline;   Drug: placebo
5 Recruiting Evaluation of Patients With Immune Function Abnormalities
Condition: Immune System Diseases
Intervention:
6 Unknown  Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
Conditions: Mevalonic Aciduria;   Mevalonate Kinase Deficiency;   Immune System Diseases;   Periodic Fever Syndromes, Hereditary;   Lipid Metabolism, Inborn Errors
Intervention:
7 Recruiting Pharmacokinetics Study of Gamma-aminobutyric Acid
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 1;   Glucose Metabolism Disorders;   Metabolic Diseases;   Endocrine System Diseases;   Autoimmune Diseases;   Immune System Diseases
Intervention:
8 Recruiting Micronutrient Supplementation and Incidence of Common Cold
Condition: Immune System Diseases
Interventions: Dietary Supplement: vitamines and minerals;   Dietary Supplement: placebo
9 Unknown  Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU)
Conditions: Nervous System Diseases;   Respiratory Tract Diseases;   Cardiovascular Diseases;   Immune System Diseases
Intervention: Drug: Oxygen
10 Recruiting Detection and Characterization of Infections and Infection Susceptibility
Conditions: Immune Disorders;   Chronic Granulomatous Disease;   Genetic Immunological Deficiencies;   Hyperimmunoglobulin-E Recurrent Infection Syndrome;   Recurrent Infections;   Unknown Immune Deficiency;   GATA2 Deficiency (MonoMAC),;   Nontuberculous Mycobacterial Infections;   Hyper IgE (Job s) Syndrome;   Leukocyte Adhesion Deficiency;   Susceptibility to Disseminated Infections;   Primary Immune Deficiency Disease (PIDD)
Intervention:
11 Recruiting Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols
Conditions: Inflammatory Disease;   Autoimmune Disease;   Immunologic Disease;   Healthy Volunteers
Intervention:
12 Recruiting Novel Genetic Disorders of the Immune System
Condition: Rare Immune Disorders
Intervention:
13 Not yet recruiting Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status
Conditions: Inflammatory Disorder of Immune System;   Sepsis
Interventions: Other: blood sample collection;   Drug: Midazolam;   Drug: Morphine;   Procedure: Sedation interruption
14 Recruiting Use of G-CSF to Obtain Blood Cell Precursors
Conditions: Chronic Granulomatous Disease;   Healthy;   Immunologic Disease;   Leukocyte Adhesion Deficiency Syndrome;   Severe Combined Immunodeficiency
Intervention:
15 Recruiting Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy.
Conditions: Transplantation;   Systemic Lupus Erythematosus;   Systemic Immune Disease
Intervention: Biological: HPV prophylactic vaccine Gardasil
16 Recruiting Investigation of Immune Disorders and Deficiencies
Conditions: Primary Immune Deficiencies;   Autoimmune Diseases;   Inflammatory Diseases;   Common Variable Immune Deficiencies;   Hypogammaglobulinemia
Intervention:
17 Unknown  Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis
Conditions: Arthritis, Rheumatoid;   Vitamin D Deficiency
Interventions: Drug: Placebo in arm A and Vitamin D in arm B;   Drug: vitamin D 3 for arm A ,and matching placebo for arm B
18 Recruiting Immune Disorder HSCT Protocol
Conditions: Immune Deficiency Disorders:;   Severe Combined Immunodeficiency;   Chronic Granulomatous Disease;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Hyper-IgM;   DiGeorge Syndrome;   Chediak-Higashi Syndrome;   Common Variable Immune Deficiency;   Immune Dysregulatory Disorder:;   Hemophagocytic Lymphohistiocytosis;   IPEX;   Autoimmune Lymphoproliferative Syndrome;   X-linked Lymphoproliferative Syndrome
Intervention: Drug: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
19 Recruiting Gulf Long-Term Follow-Up Study
Conditions: Cardiovascular Disease;   Hematologic Diseases;   Immunologic Disease;   Cancer;   Respiratory Function
Intervention:
20 Recruiting Participation in a Research Registry for Immune Disorders
Conditions: ADA-SCID;   Adenosine Deaminase Deficiency;   Wiskott- Aldrich Syndrome;   Primary Immunodeficiencies;   Severe Combined Immune Deficiency
Intervention:

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