A Prognosis and Predicting Genetic Study of Lung Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03234179|
Recruitment Status : Not yet recruiting
First Posted : July 31, 2017
Last Update Posted : August 1, 2017
Lung cancer is a leading cause of cancer mortality among adults worldwide. The incidence rates of lung cancer among never smoking females in some parts of East Asia are among the highest in the world. The adenocarcinoma of lung being the most frequently identified histological type is more weakly associated with smoking, and often occurs in females and never-smokers. Although family history of lung cancer has been associated with histological subtypes, the inherited susceptibility factors that affect specific histology are unknown.
Genetic factors that determine individual predisposition to lung cancer have been identified via genome-wide association studies. These known common loci, however, explain only a small fraction of the familial risk of lung cancer. The hypothesis of this study is that there are genetic factors that confer inherited susceptibility among patients with primary non-small-cell lung cancer (NSCLC).
|Condition or disease|
|Lung Cancer Genetic Predisposition to Disease|
|Study Type :||Observational|
|Estimated Enrollment :||500 participants|
|Official Title:||A Prognosis and Predicting Genetic Study of Lung Cancer|
|Estimated Study Start Date :||August 1, 2017|
|Estimated Primary Completion Date :||August 1, 2020|
|Estimated Study Completion Date :||August 1, 2037|
- Genetic information of lung cancer patients [ Time Frame: One week after the study subjects sign the permit of informed consents ]Collect study subjects' blood sample and analysis with Genome-wide SNP genotyping
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03234179
|Contact: Tung-Ming Tsai, MDemail@example.com|
|Contact: Jin-Shing Chen, PhDfirstname.lastname@example.org|
|Study Director:||Jin-Shing Chen, PhD||National Taiwan University Hospital|