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Trial record 2 of 95 for:    DIAS 4

Protection Against Benzene Toxicity

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00011453
First Posted: February 23, 2001
Last Update Posted: December 9, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
  Purpose
We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.

Condition
Leukemia Aplastic Anemia

Study Type: Observational
Study Design: Primary Purpose: Screening
Time Perspective: Prospective
Official Title: NQO1 in Protection Against Benzene Toxicity

Resource links provided by NLM:


Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Study Start Date: July 1998
Estimated Study Completion Date: June 2001
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00011453


Locations
United States, Colorado
University of Colorado Health Sciences Center
Denver, Colorado, United States, 80262
Sponsors and Collaborators
National Institute of Environmental Health Sciences (NIEHS)
  More Information

ClinicalTrials.gov Identifier: NCT00011453     History of Changes
Other Study ID Numbers: 9554-CP-001
First Submitted: February 21, 2001
First Posted: February 23, 2001
Last Update Posted: December 9, 2005
Last Verified: July 2002

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
NQO1
DT-diaphorase
Benzene
Leukemia
Aplastic anemia

Additional relevant MeSH terms:
Anemia, Aplastic
Anemia
Hematologic Diseases
Bone Marrow Diseases