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Functional Impact of Interval Training on Muscle Mass and Strength in Obese Adults

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ClinicalTrials.gov Identifier: NCT04693117
Recruitment Status : Completed
First Posted : January 5, 2021
Last Update Posted : August 30, 2021
Sponsor:
Information provided by (Responsible Party):
Riphah International University

Study Description
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Brief Summary:

The primary objective was to investigate the effectiveness of interval training and to evaluate the best available method for measuring body composition and functional capacity.

Thirty obese subjects consecutively voluntarily participated in the current study. They ranked sedentary according to their level of activity (≥ 30-minute moderate physical activity 3days/wk). The training sessions were divided into the warm-up phase, training phase and a cool-down phase. The training programs were completed 3days/week for 12 weeks. Body composition was calculated by skinfold thickness method and bio-impedance before and after training. Similarly, aerobic capacities were measured by lactate threshold testing and by Astrand submaximal testing.


Condition or disease Intervention/treatment Phase
Obese Muscle Strength Interval Training Other: Interval Training Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Functional Impact of Interval Training on Muscle Mass and Strength in Obese Adults
Actual Study Start Date : June 5, 2019
Actual Primary Completion Date : August 28, 2019
Actual Study Completion Date : December 28, 2019
Arms and Interventions
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Arm Intervention/treatment
Experimental: Study Group
Participants were voluntarily participated by non-probability consecutive sampling. It was a one group study with a limitation of non-randomization. The interventional group had performed interval training for 12 weeks, 3 days/week (figure 1). They sedentary conferring to activity level (≥ 30-minute, 3 days/weeks, moderate-intensity physical activity). They were not participated in any interval training program before participating in the study from six months. Written consent was taken after demonstration of the purpose, procedure, and related pros and cons. They were instructed to participate regularly in interval training.
 Other: Interval Training
All individual of interventional group participated in an interval training program, which comprised of 3 days/week for twelve weeks. A booklet was given to each participant containing instructions and guideline about interval training. The interval training program was introduced as prescribed previously.17 After the workout, a cool down period of 5 minutes was given during which they perform paddling with low speed. All training program was supervised by a qualified physical therapist.


Outcome Measures
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Primary Outcome Measures :
  1. Anthropometric measurement (Body Mass Index) [ Time Frame: 3 months ]

    Body Mass Index:

    BMI Weight Status Below 18.5 Underweight 18.5 - 24.9 Normal or Healthy Weight 25.0 - 29.9 Overweight 30.0 and Above Obese


  2. Functional capacity [ Time Frame: 3 Months ]

    The functional capacity was assessed by lactate threshold level and by Astrand submaximal testing by using standardized protocol.

    Lactate inflection point (LIP), is the exercise intensity at which the blood concentration of lactate and/or lactic acid begins to increase rapidly. It is often expressed as 85% of maximum heart rate or 75% of maximum oxygen intake.


  3. Anthropometric measurement (Lean body mass) [ Time Frame: 3 months ]
    Lean body mass:Lean body mass is calculated as the difference between total body weight and body fat weight, or more simply, the weight of everything except the fat. The range of lean body mass considered to be healthy is around 70% - 90% with women being towards the lower end of the range and men higher.

  4. Functional Capacity [ Time Frame: 3 months ]

    The functional capacity was assessed by Astrand submaximal testing by using standardized protocol.

    The Astrand Test is a submaximal cycle ergometer aerobic fitness test best suited in rehabilitation and health purposes. description: Athletes pedal on a cycle ergometer at a constant workload for 7 minutes. Heart rate is measured every minute, and the steady state heart rate is determined.



Eligibility Criteria
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Ages Eligible for Study:   30 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 30 obese (BMI ≥ 30) and
  • Sedentary lifestyle subjects (sample size was calculated by using WHO sample size calculator)
  • Age 30-45 years and
  • Hypercholesteremia

Exclusion Criteria:

  • hypertension,
  • diabetes,
  • cardiovascular diseases
  • systemic diseases
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04693117


Locations
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Pakistan
Riphah Rehabilitation Center
Lahore, Punjab, Pakistan, 54000
Sponsors and Collaborators
Riphah International University
Investigators
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Principal Investigator: Maryam Shabbir, PhD* Riphah International University
More Information
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Publications:

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Responsible Party: Riphah International University
ClinicalTrials.gov Identifier: NCT04693117    
Other Study ID Numbers: REC/Lhr/338
First Posted: January 5, 2021    Key Record Dates
Last Update Posted: August 30, 2021
Last Verified: August 2021
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Riphah International University:
Obesity
Body composition
Exercise testing
Additional relevant MeSH terms:
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Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight