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The Reflex Mechanism Underlying Neuromuscular Effects Of The Whole Body Vibration (WBV-IRM)

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ClinicalTrials.gov Identifier: NCT04516798
Recruitment Status : Completed
First Posted : August 18, 2020
Last Update Posted : October 27, 2020
Sponsor:
Information provided by (Responsible Party):
Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Study Description
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Brief Summary:
This study was conducted to determine whether the spinal reflex mechanism underlying the neuromuscular effects of whole body vibration (WBV) is tonic vibration reflex. Local and whole body vibration reflex latencies were measured in young adult healthy volunteers.

Condition or disease Intervention/treatment Phase
Reflex, Ankle, Decreased Other: vibration Not Applicable

Detailed Description:

A total of eight volunteers were included according to the inclusion and exclusion criteria. The subjects were vibrated while standing upright with the WBV device (PowerPlate® Pro5). The 30, 35 and 40 Hz WBVs were applied for thirty seconds for each frequency with an amplitude of 2 mm. In the same session, 100, 135 and 150 Hz local vibrations were applied to the right Achilles tendon for thirty seconds for each frequency. 100, 135 and 150 Hz local vibrations were then applied to the right heel for thirty seconds for each frequency with an interval of five seconds. Vibration stimuli were recorded accelerometers. Reflex muscle responses were recorded from the right soleus muscle at a sampling rate of 40 KHz. Recording electrodes were placed on the belly of the right soleus muscle and the ground electrode was placed on the right medial malleolus.

The data were recorded with the PowerLab device, the records were processed and analyzed offline from the LabChart program. After the EMG records are filtered and rectified, reflex latencies were measured by cumulative averaging method using the accelerometer records as triggers (Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Türker KS.A new method to determine reflex latency induced by high rate stimulation of the nervous system.Front Hum Neurosci.2014 Jul 18; 8: 536.doi: 10.3389 / fnhum.2014.00536). After determining the Achilles tendon vibration reflex latency and the reflex latency induced by WBV, it was compared with statistical methods.

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 8 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Intervention Model Description: Self controlled experimental study
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: The Reflex Mechanism Underlying The Neuromuscular Effects Of The Whole Body Vibration
Actual Study Start Date : October 5, 2020
Actual Primary Completion Date : October 7, 2020
Actual Study Completion Date : October 7, 2020
Arms and Interventions
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Arm Intervention/treatment
Experimental: Experiment
Local and whole body vibration were applied
 Other: vibration
local and whole-body vibration were applied


Outcome Measures
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Primary Outcome Measures :
  1. reflex latency [ Time Frame: during intervention, an average of 8 minutes ]
    The time between the vibration stimulus and the reflex muscle response triggered by it was defined as the latency.


Eligibility Criteria
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Ages Eligible for Study:   20 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy
  • Young adult (20-40 years old)
  • Both gender
  • Volunteer

Exclusion Criteria:

  • Cardiac disorder (Rhythm / conduction disorder, Cardiac pacemaker, Ischemic heart disease)
  • Finding or suspected active deep vein thrombosis,
  • History of deep vein thrombosis and pulmonary embolism,
  • Orthostatic hypotension
  • Hypertension
  • Presence of fracture in the lower limb
  • Achilles Contractures
  • Active inflammatory, rheumatological or infectious disease in the lower limb
  • Peripheral nerve lesions such as polyneuropathy, radiculopathy in the lower limb
  • Those with a history of Achilles tendinopathy / bursitis
  • Those with a history of kidney stones
  • Patients with dizziness and balance problems,
  • Cases with lesions on the skin surface where electrodes were attached
  • Those with communication-cooperation problems
  • Having a history of panic attacks
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04516798


Locations
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Turkey
Istanbul Physical Medicine Rehabilitation Training & Research Hospital
İstanbul, Turkey, 34173
Sponsors and Collaborators
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Investigators
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Principal Investigator: Ilhan Karacan, Assoc Prof Istanbul Physical Medicine Rehabilitation Training & Research Hospital
More Information
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Publications of Results:

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Responsible Party: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
ClinicalTrials.gov Identifier: NCT04516798    
Other Study ID Numbers: ISTANBULPMR
First Posted: August 18, 2020    Key Record Dates
Last Update Posted: October 27, 2020
Last Verified: October 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Istanbul Physical Medicine Rehabilitation Training and Research Hospital:
whole body vibration
tonic vibration reflex
muscle spindle
Additional relevant MeSH terms:
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Reflex, Abnormal
Neurologic Manifestations
Nervous System Diseases