Dual-task Training for Function in MCI
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|ClinicalTrials.gov Identifier: NCT04059705|
Recruitment Status : Not yet recruiting
First Posted : August 16, 2019
Last Update Posted : October 9, 2020
|Condition or disease||Intervention/treatment||Phase|
|Mild Cognitive Impairment||Behavioral: Dual-Task Training||Not Applicable|
Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and severe dementia associated with Alzheimer's disease (AD). In the United States about 20% of older adults have MCI, and approximately 15% per year of those with MCI will progress to AD. With our rapidly aging society, we are approaching a public health crisis for which we are not fully prepared. Impaired cognitive function in aging can have far-reaching and devastating impacts on functional status, ability to maintain independence, and overall quality of life. Unfortunately, the therapeutic options to slow progression of cognitive decline in aging are limited.
Dual-task training that involves simultaneous cognitive and motor challenges improves certain domains of both cognitive and motor function in older adults with MCI. However, we do not yet know the optimal methods of delivering this high-impact potential therapy in community-based settings with unique limitations and strengths. Therefore, the aims are to; 1) test the feasibility of conducting a community-based dual-task (thinking while exercising) physical activity intervention among adults, 65 years or older, with MCI; and 2) examine the impact of dual-task training on attention and motor function among adults, 65 years or older, with MCI.
To accomplish these aims the investigators will conduct an 12-week, dual-task training program using the SmartFit Multisensory Fitness System (Oxnard, CA) among older adults with MCI. Our group-based training program involves two 1-hour training sessions per week, designed to simultaneously engage the mind and body, while promoting self-efficacy. Attention and motor function will be assessed prospectively.
The investigators anticipate that findings from this trial will inform development of methods to bring evidence-based, non-invasive therapies into communities in need, in order to preserve function, independence, and quality of life well into older age.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||24 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||This study utilizes a one-group design with repeated measures.|
|Masking:||None (Open Label)|
|Official Title:||The Impact of Dual-task Training on Attention and Motor Function in Older Adults With Mild Cognitive Impairment|
|Estimated Study Start Date :||January 4, 2021|
|Estimated Primary Completion Date :||January 4, 2021|
|Estimated Study Completion Date :||February 15, 2021|
Experimental: Dual-Task Intervention
This study arm will receive the dual-task training program.
Behavioral: Dual-Task Training
The ThinkFIT intervention will involve two days per week participation in simultaneous cognitive and motor training activities, facilitated by the SMARTFit Multisensory FItness System.
Other Name: ThinkFIT Intervention, SMARTFit Multisensory Fitness System
- Change in Motor Function from baseline to 12 weeks [ Time Frame: baseline, week 6, week 12 ]Change in motor function will be assessed prospectively using the Short Physical Performance Battery.
- Change in Attention from baseline to 12 weeks [ Time Frame: baseline, week 6, week 12 ]Attention will be assessed prospectively using the Stroop Task and Trail-making Test.
- Change in Exercise Self Efficacy from baseline to 12 weeks [ Time Frame: baseline, week 12 ]Self efficacy for exercise will be assessed using the Self Efficacy for Exercise Scale. Total score is derived by summing the individual scores for each question. Scoring range for this instrument is 0 - 90 points with higher scores representing better outcomes.
- Outcome Expectations for Exercise from baseline to 12 weeks [ Time Frame: baseline, week 12 ]Outcome Expectations for exercise will be assessed using the Outcome Expectations for Exercise Scale. This instrument has 9 total items. Total score is derived by summing the responses to these items and dividing by the number of responses. Scoring is out of 9 points, with higher scores demonstrating higher outcomes expectations.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04059705
|Contact: Nikhil Satchidanand, PhDfirstname.lastname@example.org|
|Principal Investigator:||Nikhil Satchidanand, PhD||University at Buffalo, State University of New York|