Mat Pilates and Vascular Function in Obese Females

• ClinicalTrials.gov Identifier: NCT03907384
• Recruitment Status: Completed
• First Posted: April 9, 2019
• Last Update Posted: October 30, 2020
• Sponsor: Marymount University
• Collaborators: Busan University; Texas Tech University; University of Isfahan
• Information provided by (Responsible Party): Alexei Wong, Marymount University

Study Description

Brief Summary:

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.

Condition or disease	Intervention/treatment	Phase
Obese; Elevated Blood Pressure	Behavioral: Mat Pilates training	Not Applicable

Detailed Description:

Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.

Study Design

• Study Type: Interventional (Clinical Trial)
• Actual Enrollment: 28 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Outcomes Assessor)
• Primary Purpose: Treatment
• Official Title: The Effects of Mat Pilates Training on Vascular Function in Obese Premenopausal Women With Elevated Blood Pressure
• Actual Study Start Date: April 1, 2018
• Actual Primary Completion Date: October 30, 2018
• Actual Study Completion Date: October 30, 2018

Arms and Interventions

Arm	Intervention/treatment
Experimental: Mat Pilates training; The MPT group participated in 3-one hour supervised training sessions per week for 12 weeks. All MP sessions were performed in nonconsecutive days. The MP sessions were divided into the following stages: initial warm up and stretching (10 min), general conditioning consisting of MP exercises (40 min) and stretching and cooling down (10 min). The participants performed 12 basic MP exercises (one set of 6-10 repetitions was performed per exercise). Breathing, a core principle of MP, was performed by forced but controlled inspirations and exhalations, while relaxing and contracting the abdomen, respectively. All sessions were supervised by a certified MP instructor.	Behavioral: Mat Pilates training; This group completed 12-weeks of training
No Intervention: Control; Participants in the non-exercising control group did not participate in a supervised exercise program and visited the laboratory at the same frequency as participants in the swim intervention and underwent recreational activities such as board games

Outcome Measures

Primary Outcome Measures :

1. Arterial Stiffness [ Time Frame: 12 weeks ]
   via Pulse Wave Velocity

Secondary Outcome Measures :

1. Systolic and Diastolic Blood Pressure [ Time Frame: 12 weeks ]
   Automatic BP monitor
2. Pressure Wave Reflection [ Time Frame: 12 weeks ]
   via Augmentation Index
3. Endothelial Function [ Time Frame: 12 weeks ]
   via plasma nitric oxide

Eligibility Criteria

• Ages Eligible for Study: 18 Years to 35 Years (Adult)
• Sexes Eligible for Study: Female
• Gender Based Eligibility: Yes
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• body mass index 30-40 kg/m2
• <1 h of regular exercise per week in the previous year
• systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP
• Nonsmokers

Exclusion Criteria:

• body mass index ˂30 and ≥40 kg/m2
• chronic diseases
• taking oral contraceptives
• pregnancy

Contacts and Locations

Locations

United States, Nebraska

University of Nebraska

Omaha, Nebraska, United States, 68022

Sponsors and Collaborators

Marymount University

Busan University

Texas Tech University

University of Isfahan

More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Wong A, Figueroa A, Fischer SM, Bagheri R, Park SY. The Effects of Mat Pilates Training on Vascular Function and Body Fatness in Obese Young Women With Elevated Blood Pressure. Am J Hypertens. 2020 May 21;33(6):563-569. doi: 10.1093/ajh/hpaa026.

• Responsible Party: Alexei Wong, Assistant Professor, Marymount University
• ClinicalTrials.gov Identifier: NCT03907384
• Other Study ID Numbers: 1342019
• First Posted: April 9, 2019
• Last Update Posted: October 30, 2020
• Last Verified: October 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:

Hypertension; Vascular Diseases; Cardiovascular Diseases