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Prostate Cancer Risk in Firefighters

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03893123
Recruitment Status : Unknown
Verified March 2020 by Jarle Jakobsen, Cancer Registry of Norway.
Recruitment status was:  Active, not recruiting
First Posted : March 28, 2019
Last Update Posted : March 4, 2020
Sponsor:
Collaborators:
Cancer Registry of Norway
Extrastiftelsen
National Institute of Occupational Health
Norwegian Confederation of Trade Unions
Fagforbundet
Gjensidige Foundation
Norwegian Cancer Society
Norwegian Firefighters Fight Cancer
Norwegian Labour Inspection Authority
Information provided by (Responsible Party):
Jarle Jakobsen, Cancer Registry of Norway

Study Description
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Brief Summary:
Firefighters have been shown to be at increased risk for various types of cancer, including prostate cancer. This study will try to explore possible reasons for this increase in risk. A study group at the Cancer Registry of Norway is creating a cohort of Norwegian firemen employed from 1960 onwards. A job exposure matrix (JEM) is also being constructed, examining different types of exposure to potentially cancer-inducing agents and activities, and how these have changed historically. Examples include exposure to fire-smoke, shiftwork, diesel exhaust and regular health check-ups. By linking the cohort with data from the Cancer Registry of Norway and the JEM the investigators can examine which exposure assessments, if any, are related to an increased risk of prostate cancer.

Condition or disease Intervention/treatment
Prostatic Cancer Other: Observational study, prostate cancer is outcome of interest

Study Design
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Study Type : Observational
Actual Enrollment : 4500 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Prostate Cancer Risk in Firefighters: Its Association to Qualitative and Quantitative Indicators of Exposure
Actual Study Start Date : January 1, 2018
Actual Primary Completion Date : February 1, 2020
Estimated Study Completion Date : December 2021

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Prostate Cancer

Groups and Cohorts
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Group/Cohort Intervention/treatment
Firefighters Other: Observational study, prostate cancer is outcome of interest
Observational study


Outcome Measures
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Primary Outcome Measures :
  1. Incidence of prostate cancer [ Time Frame: From January 1st 1960 until December 31st 2018 ]
    As reported to the Cancer Registry of Norway


Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Norwegian males
Criteria

Inclusion Criteria:

  • Work as firefighter as recorded by the participating fire stations

Exclusion Criteria:

  • Any other occupation, including chimney sweepers
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03893123


Locations
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Norway
Cancer Registry of Norway
Oslo, Norway, 0304
Sponsors and Collaborators
Oslo University Hospital
Cancer Registry of Norway
Extrastiftelsen
National Institute of Occupational Health
Norwegian Confederation of Trade Unions
Fagforbundet
Gjensidige Foundation
Norwegian Cancer Society
Norwegian Firefighters Fight Cancer
Norwegian Labour Inspection Authority
More Information
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Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
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Responsible Party: Jarle Jakobsen, PhD-student, Cancer Registry of Norway
ClinicalTrials.gov Identifier: NCT03893123    
Other Study ID Numbers: 2016/2282
First Posted: March 28, 2019    Key Record Dates
Last Update Posted: March 4, 2020
Last Verified: March 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
 Neoplasms by Site
Neoplasms
Prostatic Diseases