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Osteoarticular Infections With Pneumococcal

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ClinicalTrials.gov Identifier: NCT03852784
Recruitment Status : Completed
First Posted : February 25, 2019
Last Update Posted : January 19, 2022
Sponsor:
Information provided by (Responsible Party):
Eugénie MABRUT, Hospices Civils de Lyon

Study Description
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Brief Summary:
Osteoarticular infections at pneumococcal are rare, potentially serious and remain under diagnosed. They represent 3 at 10% of the arthritis septic in the literature. 190 cases have been published of 1965 at 2003. They represent 0.3% at 0.6% of the bacteraemia at Streptococcus peumoniae.

Condition or disease Intervention/treatment
Bone and Joint Infection Other: Bone and joint infection with Streptococcus peumoniae

Study Design
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Study Type : Observational
Actual Enrollment : 33 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Osteoarticular Infections With Pneumococcal
Actual Study Start Date : January 1, 2019
Actual Primary Completion Date : March 1, 2019
Actual Study Completion Date : April 1, 2020
Groups and Cohorts
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Group/Cohort Intervention/treatment
Bone and joint infection with Streptococcus peumoniae
Patients having had an osteoarticular infection with Streptococcus peumoniae
 Other: Bone and joint infection with Streptococcus peumoniae
description of the osteoarticular infection with Streptococcus peumoniae


Outcome Measures
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Primary Outcome Measures :
  1. Description and rate of bone or joint infection with S. pneumoniae [ Time Frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption ]
    Description of the type of infection due to S. pneumoniae : patients and type of implant, profile of the bacterium associated in the infection, medical and chirurgical treatment


Secondary Outcome Measures :
  1. Rate of Treatment Failure [ Time Frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption ]
    Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin


Eligibility Criteria
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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
patients having had a bone and joint infection with S pneumoniae, with or without device managed at the Croix-Rousse hospital
Criteria

Inclusion Criteria:

  • patients having had a bone and joint infection with S pneumoniae, with or without device.

Exclusion Criteria:

  • none
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03852784


Locations
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France
Hospices Civils de Lyon
Lyon, France, 69004
Sponsors and Collaborators
Hospices Civils de Lyon
Investigators
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Study Director: Tristan Ferry, Md,PhD Hospices Civils de Lyon
More Information
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Additional Information:

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Responsible Party: Eugénie MABRUT, clinical reserach assistant, Hospices Civils de Lyon
ClinicalTrials.gov Identifier: NCT03852784    
Other Study ID Numbers: 19-074
First Posted: February 25, 2019    Key Record Dates
Last Update Posted: January 19, 2022
Last Verified: April 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Eugénie MABRUT, Hospices Civils de Lyon:
Bone and Joint Infection
Streptococcus peumoniae
Additional relevant MeSH terms:
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Infections
Communicable Diseases
Disease Attributes
Pathologic Processes